Frontiers in Cardiovascular Medicine

JANUARY 16, 2025

Calcific aortic valve disease (CAVD) is a common cardiovascular condition in the elderly population. Research has shown that lncRNAs participate in the pathological process underlying CAVD by regulating osteogenic differentiation and inflammatory response of valve interstitial cells.

Aortic valve 52

Aortic valve Aortic Stenosis Research 52

Heart BMJ

FEBRUARY 12, 2025

Background Bicuspid aortic valve (BAV) is the most common congenital heart defect in adults, often leading to complications such as thoracic aortic aneurysms and aortic stenosis. While BAV is frequently associated with 22q11.2 This study is aimed to assess the role of rare 22q11.2 region (18–24 Mb).

Aortic valve 52

Aortic valve Bicuspid/Mitral Aortic Aneurysm 52

Heart BMJ

FEBRUARY 26, 2025

A significant proportion of patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) have concomitant coronary artery disease (CAD). The best way to treat these patients is contentious.

Coronary Artery Disease 59

Coronary Artery Disease Stenosis Aortic Aortic valve 59

Open Heart

JANUARY 19, 2025

Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. Despite advancements in emergency interventions, the optimal treatment approach remains uncertain. Methods A systematic literature review and meta-analysis was performed.

Cardiogenic Shock 52

Cardiogenic Shock Aortic Stenosis Aortic valve 52

Frontiers in Cardiovascular Medicine

FEBRUARY 17, 2025

IntroductionSince TAVR was approved for lower-risk aortic stenosis (AS) patients, managing post-implantation conduction disturbances has become crucial, especially with self-expanding heart valves (SEV).

Pacemaker 52

Pacemaker Aortic Stenosis Aortic valve 52

Heart BMJ

JANUARY 29, 2025

Background Subclinical leaflet thrombosis (SLT) is a common complication after transcatheter aortic valve replacement (TAVR). Methods This prospective cohort study consecutively enrolled patients with severe symptomatic aortic stenosis who underwent successful TAVR.

Aortic valve 52

Aortic valve Thrombosis Aortic Technology 52

American College of Cardiology

MAY 24, 2024

What is the relationship between aortic valve calcification (AVC) and aortic stenosis (AS) severity in patients with suspected low-flow low-gradient AS?

Aortic valve 71

Aortic valve Aortic Stenosis Article 71

Heart BMJ

JULY 10, 2024

Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).

Aortic valve 98

Aortic valve Aortic Quality of Life TAVR 98

Frontiers in Cardiovascular Medicine

AUGUST 7, 2024

Aortic Stenosis (AS) is a common condition with an estimated pooled prevalence of all AS in the elderly population at around 12.4%, with that of severe AS estimated to be around 3.4%. In the past, surgical aortic valve replacement was the primary treatment option for severe AS for decades.

Aortic valve 98

Aortic valve Aortic TAVR Peripheral Arterial Disease 98

DAIC

MARCH 25, 2024

The global, randomized trial ( envisiontrial.com ) will evaluate the safety and effectiveness of Abbott’s minimally invasive Navitor transcatheter aortic valve implantation (TAVI) system in approximately 1,500 patients at intermediate or low surgical risk with severe aortic stenosis (narrowing of the aortic valve).

Stenosis 115

Stenosis Aortic Aortic valve Heart Valves 115

Med Page Today

OCTOBER 28, 2024

(MedPage Today) -- Transcatheter aortic valve replacement (TAVR) yielded clinical benefit when given early in the disease process while patients still had no symptoms or other indication for aortic valve replacement, according to the EARLY TAVR.

TAVR 102

TAVR Aortic Aortic valve Stenosis 102

DAIC

MARCH 31, 2025

Data shows, versus surgery, the Evolut transcatheter aortic valve replacement (TAVR) system delivers a numerically lower rate of all-cause mortality or disabling stroke at five years, strong valve performance and durable clinical outcomes. Reardon, M.D.,

TAVR 52

TAVR Stenosis Aortic Outcomes 52

JAMA Cardiology

JULY 16, 2024

This meta-analysis evaluates lipoprotein(a) concentrations and hemodynamic progression in patients with aortic stenosis.

Stenosis 80

Stenosis Aortic valve Aortic 80

DAIC

JANUARY 29, 2024

Getty Images milla1cf Mon, 01/29/2024 - 14:24 January 29, 2024 — Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis , many hospitals are still opting for a nonsurgical approach in patients under 60—possibly with poorer survival rates.

Aortic valve 111

Aortic valve TAVR Aortic Outcomes 111

American College of Cardiology

SEPTEMBER 18, 2024

The goal of the AVATAR trial was to evaluate aortic valve replacement (AVR) compared with conservative therapy among patients with asymptomatic severe aortic stenosis.

Aortic valve 60

Aortic valve Aortic Stenosis Article 60

Open Heart

FEBRUARY 27, 2024

Objectives The clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with aortic stenosis (AS) and concomitant active cancer remain insufficiently explored. This study aimed to assess the midterm outcomes of TAVR in patients diagnosed with AS and active cancer.

Aortic valve 98

Aortic valve Cancer Aortic TAVR 98

Heart BMJ

FEBRUARY 26, 2025

In the 22 years since Professor Alain Cribier performed the first transcatheter aortic valve implantation (TAVI) in Rouen in France, treatment pathways for patients with aortic valve stenosis have evolved rapidly.

Aortic valve 59

Aortic valve Aortic Stenosis 59

American College of Cardiology

MAY 29, 2024

In this week’s View, Dr. Eagle looks at the diagnostic value of aortic valve calcification levels in the assessment of low-gradient aortic stenosis.

Aortic valve 55

Aortic valve Aortic Stenosis Article 55

JAMA Cardiology

MARCH 25, 2025

This Viewpoint discusses the use of aortic valve intervention vs watchful waiting for patients with asymptomatic aortic stenosis.

Aortic valve 42

Aortic valve Aortic Stenosis 42

Journal of Cardiothoracic Surgery

APRIL 19, 2024

Patients with severe aortic stenosis (AS) and left ventricular (LV) dysfunction demonstrate improvement in left ventricular injection fraction (LVEF) after aortic valve replacement (AVR). The timing and magnit.

Aortic valve 52

Aortic valve Aortic Stenosis Outcomes 52

American College of Cardiology

FEBRUARY 26, 2025

In this weeks View, Dr. Eagle looks at the potential exposure-dependent protective effect of SGLT2 inhibitors on aortic valve stenosis progression.

Aortic valve 59

Aortic valve Stenosis Aortic AFIB 59

Frontiers in Cardiovascular Medicine

FEBRUARY 6, 2025

IntroductionClinical evidence highlighting the efficacy and safety of transcatheter aortic valve replacement (TAVR) and the 2019 Food and Drug Administration (FDA) approval for TAVR in low-risk (younger) patients has created a demand for durable and long-lasting bioprosthetic heart valve (BHV) leaflet materials.

Heart Valves 52

Heart Valves Aortic TAVR Aortic valve 52

Heart BMJ

APRIL 15, 2024

Objective Aortic stenosis (AS) shares pathophysiological similarities with atherosclerosis including active inflammation. CT attenuation of perivascular adipose tissue provides a measure of vascular inflammation that is linked to prognosis and has the potential to be applied to the aortic valve. HU, p=0.099).

Aortic valve 52

Aortic valve Aortic Stenosis Atherosclerosis 52

Frontiers in Cardiovascular Medicine

FEBRUARY 20, 2024

Background Closure of paravalvular leak (PVL) regurgitation after self-expandable (SE) transcatheter aortic valve implantation (TAVI) may be more challenging than after balloon-expandable (BE) valve implantation. MN, USA).

Aortic valve 111

Aortic valve Aortic Atrial Fibrillation Heart Failure 111

American College of Cardiology

APRIL 8, 2024

The goal of the DEDICATE-DZHK6 trial was to evaluate transcatheter aortic valve implantation (TAVI) compared with surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis and low to intermediate surgical risk.

Aortic valve 55

Aortic valve Stenosis Aortic Article 55

Becker's Hospital Review - Cardiology

MAY 14, 2024

UPMC Harrisburg pioneers new transcatheter aortic valve replacement system, providing improved lifetime management for patients with aortic valve stenosis.

Aortic valve 92

Aortic valve TAVR Aortic Stenosis 92

American College of Cardiology

APRIL 22, 2024

What is the 5-year incidence of valve reintervention after self-expanding CoreValve/Evolut transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR)?

TAVR 68

TAVR Aortic Aortic valve Stenosis 68

American College of Cardiology

FEBRUARY 12, 2024

The goal of the NOTION trial was to compare outcomes after transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) in unselected patients with severe degenerative aortic stenosis.

Aortic valve 51

Aortic valve Aortic TAVR Stenosis 51

Journal of Cardiothoracic Surgery

JULY 29, 2024

Transcatheter aortic valve replacement (TAVR) has increased in utilization since its approval for management of aortic stenosis patients across all risk strata. We report a rare case of aortic valve leaflet av.

Aortic valve 52

Aortic valve TAVR Aortic Stenosis 52

Frontiers in Cardiovascular Medicine

JANUARY 2, 2024

Bicuspid aortic valve (BAV) is a common congenital heart condition that can lead to some valve-related complications, such as aortic stenosis and/or regurgitation, and is often associated with aortic root dilation.

Aortic valve 64

Aortic valve Bicuspid/Mitral Aortic Outcomes 64

Cardiology Update

FEBRUARY 26, 2024

Transcatheter aortic valve replacement (TAVR) is the standard treatment for severe aortic stenosis, but post-TAVR leaflet thrombus, identified by hypoattenuated leaflet thickening (HALT), poses potential risks like cerebral thromboembolic events. had thrombus at any aortic valve complex. Specifically, 14.2%

TAVR 122

TAVR Aortic valve Outcomes Aortic 122

American College of Cardiology

APRIL 4, 2024

The goal of the VIVA trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis and a small aortic annulus.

Aortic valve 46

Aortic valve Aortic Stenosis TAVR 46

American College of Cardiology

OCTOBER 28, 2024

The goal of the EARLY TAVR trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with clinical surveillance among patients with asymptomatic severe aortic stenosis (stage C aortic stenosis).

TAVR 59

TAVR Stenosis Aortic Aortic valve 59

MIBHS

DECEMBER 30, 2022

A normal functioning aortic valve has three leaflets, usually referred to as cusps, and is positioned at the end of the left ventricle. This valve is the main pump that delivers oxygenated blood to the entire body. Today we take a deep dive into aortic valve replacement, so you can have the knowledge you need.

Aortic valve 52

Aortic valve Aortic Stenosis Hospital 52

Medical Xpress - Cardiology

OCTOBER 29, 2024

Findings from the TAVR UNLOAD study found limited benefits of transcatheter aortic valve replacement (TAVR) in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and moderate aortic stenosis (AS).

Aortic valve 45

Aortic valve Aortic Heart Failure Stenosis 45

Journal of Cardiothoracic Surgery

FEBRUARY 3, 2024

Anomalous aortic origin of the coronary artery (AAOCA) is a rare congenital heart disease. Therefore, optimal indications for surgery in patients with severe aortic valve stenosis (AS) complicated by AAOCA rem.

Aortic valve 52

Aortic valve Aortic Stenosis Congenital Heart Disease 52

NEJM Journal Watch - Cardiology

NOVEMBER 8, 2024

A strategy of early AVR was superior to clinical surveillance due to a reduction in hospitalizations.

Aortic valve 75

Aortic valve Aortic Stenosis Hospital 75