Aortic Stenosis, Heart Failure, and Aortic Valve Replacement
JAMA Cardiology
OCTOBER 15, 2024
This narrative review analyzes associations among heart failure, aortic stenosis, and aortic valve replacement.
Aortic Aortic valve Stenosis 
Aortic Valve ReplAcemenT versus Conservative Treatment in Asymptomatic SeveRe Aortic Stenosis
American College of Cardiology
SEPTEMBER 18, 2024
The goal of the AVATAR trial was to evaluate aortic valve replacement (AVR) compared with conservative therapy among patients with asymptomatic severe aortic stenosis.
Aortic valve 
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Aortic Valve Calcification in Low-Gradient Aortic Stenosis
American College of Cardiology
MAY 24, 2024
What is the relationship between aortic valve calcification (AVC) and aortic stenosis (AS) severity in patients with suspected low-flow low-gradient AS?
Aortic valve 72
72 
Transcatheter aortic valve replacement in patients with systolic heart failure, aortic stenosis shows limited benefits
Medical Xpress - Cardiology
OCTOBER 29, 2024
Findings from the TAVR UNLOAD study found limited benefits of transcatheter aortic valve replacement (TAVR) in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and moderate aortic stenosis (AS).
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Major Win for Preemptive TAVR in Symptomless Aortic Stenosis
Med Page Today
OCTOBER 28, 2024
(MedPage Today) -- Transcatheter aortic valve replacement (TAVR) yielded clinical benefit when given early in the disease process while patients still had no symptoms or other indication for aortic valve replacement, according to the EARLY TAVR.
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Cardiopulmonary exercise testing in aortic stenosis patients before and after aortic valve replacement
Open Heart
NOVEMBER 9, 2024
Background Knowledge about how patients with symptomatic aortic stenosis (AS) perform on cardiopulmonary exercise testing (CPET) is sparse. We aimed to investigate maximal and submaximal physical capacity by CPET before and 1 year after surgical aortic valve replacement (sAVR) in patients with severe AS.
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Early transcatheter aortic valve replacement can be beneficial for asymptomatic severe aortic stenosis patients: Study
Medical Xpress - Cardiology
OCTOBER 29, 2024
The first powered randomized trial examining early intervention with transcatheter aortic valve replacement (TAVR) in patients with asymptomatic, severe aortic stenosis (AS) found this strategy to be both a safe and effective alternative to clinical surveillance (CS).
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Alternative access in transcatheter aortic valve replacement—an updated focused review
Frontiers in Cardiovascular Medicine
AUGUST 7, 2024
Aortic Stenosis (AS) is a common condition with an estimated pooled prevalence of all AS in the elderly population at around 12.4%, with that of severe AS estimated to be around 3.4%. In the past, surgical aortic valve replacement was the primary treatment option for severe AS for decades.
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Cardiawave Releases Positive Data on Non-Invasive Valvosoft Aortic Valve Therapy
DAIC
NOVEMBER 7, 2024
28, 2024 — Cardiawave SA, developer of Valvosoft Non-Invasive Ultrasound Therapy (NIUT) device for treating severe symptomatic calcific aortic stenosis (CAS), announced that the device met the primary endpoint in its pivotal study and improved or stabilized heart failure symptoms for 80.5 tim.hodson Thu, 11/07/2024 - 10:19 Oct.
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Sarcopenia and aortic valve disease
Heart BMJ
JULY 10, 2024
Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).
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Dedicated trial in women demonstrates the superiority of transcatheter vs. surgical aortic valve replacement
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.
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Aortic Valve Calcification and Aortic Stenosis, Microvascular Resistance Reserve After PCI, Microvascular Injury Patterns
American College of Cardiology
MAY 29, 2024
In this week’s View, Dr. Eagle looks at the diagnostic value of aortic valve calcification levels in the assessment of low-gradient aortic stenosis.
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TAVI Matches SAVR in Lower Risk Aortic Valve Patients: 10 year outcomes
Cardiology Update
FEBRUARY 11, 2024
The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk.
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Outcomes in patients with aortic stenosis and severely reduced ejection fraction following surgical aortic valve replacement and transcatheter aortic valve replacement
Journal of Cardiothoracic Surgery
APRIL 19, 2024
Patients with severe aortic stenosis (AS) and left ventricular (LV) dysfunction demonstrate improvement in left ventricular injection fraction (LVEF) after aortic valve replacement (AVR). The timing and magnit.
Aortic valve 52
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Abstract 4145296: Aortic Valve Hemodynamics in Liver Cirrhosis
Circulation
NOVEMBER 11, 2024
Aortic valve stenosis (AS) is often a contraindication to liver transplantation (LT). Despite the widely accepted impact of liver cirrhosis on aortic valve hemodynamics, the change in these parameters with LT or impact of AS on LT outcomes has not been described. m/s, p < 0.001) as compared to mild AS (1.5
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Lipoprotein(a) and Calcific Aortic Valve Stenosis Progression
JAMA Cardiology
JULY 16, 2024
This meta-analysis evaluates lipoprotein(a) concentrations and hemodynamic progression in patients with aortic stenosis.
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Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement for Treating Elderly Patients With Severe Aortic Stenosis and Small Aortic Annuli
American College of Cardiology
APRIL 4, 2024
The goal of the VIVA trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis and a small aortic annulus.
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Aortic valve perivascular adipose tissue computed tomography attenuation in patients with aortic stenosis
Heart BMJ
APRIL 15, 2024
Objective Aortic stenosis (AS) shares pathophysiological similarities with atherosclerosis including active inflammation. CT attenuation of perivascular adipose tissue provides a measure of vascular inflammation that is linked to prognosis and has the potential to be applied to the aortic valve. HU, p=0.099).
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Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic Stenosis
American College of Cardiology
OCTOBER 28, 2024
The goal of the EARLY TAVR trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with clinical surveillance among patients with asymptomatic severe aortic stenosis (stage C aortic stenosis).
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Surgical management of native aortic valve leaflet avulsion during TAVR
Journal of Cardiothoracic Surgery
JULY 29, 2024
Transcatheter aortic valve replacement (TAVR) has increased in utilization since its approval for management of aortic stenosis patients across all risk strata. We report a rare case of aortic valve leaflet av.
Aortic valve 52
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Heart-Valve-Surgery.Com and Medtronic Launch Novel "Aortic Stenosis Patient Activation Platform" to Empower Patients
DAIC
APRIL 25, 2024
Aortic stenosis is a narrowing of the aortic valve which prevents the aortic leaflets from opening and closing properly. Patients with aortic stenosis often have heart murmurs and experience debilitating symptoms including chest pain, dizziness, fatigue, shortness of breath and an irregular heartbeat.
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Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in patients with ADvanced heart failure
American College of Cardiology
OCTOBER 28, 2024
The goal of the TAVR UNLOAD trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with clinical surveillance among patients with chronic systolic heart failure and moderate aortic stenosis (stage B aortic stenosis).
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49 
The neo-aortic valve in patients with hypoplastic left heart syndrome is largely preserved: a serial follow-up CMR study
Frontiers in Cardiovascular Medicine
NOVEMBER 5, 2024
BackgroundIn hypoplastic left heart syndrome (HLHS) patients, neo-aortic valve regurgitation can negatively impact right ventricular (RV) function. None of the patients had significant neo-aortic valve stenosis (peak velocity >3 m/s). RF correlated with RVESVi and RVEF at the second examination.
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Randomized, Multicenter, Event-Driven Trial of TAVI Versus SAVR in Patients With Symptomatic Severe Aortic-Valve Stenosis
American College of Cardiology
APRIL 8, 2024
The goal of the DEDICATE-DZHK6 trial was to evaluate transcatheter aortic valve implantation (TAVI) compared with surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis and low to intermediate surgical risk.
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Nordic Aortic Valve Intervention
American College of Cardiology
FEBRUARY 12, 2024
The goal of the NOTION trial was to compare outcomes after transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) in unselected patients with severe degenerative aortic stenosis.
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Researchers ID Genetic Variants Linked to Bicuspid Aortic Valve Disease
DAIC
SEPTEMBER 4, 2024
1, 2024 — Researchers at UTHealth Houston have identified genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications. tim.hodson Wed, 09/04/2024 - 15:53 Sept.
Aortic valve 52
52 
Systematic review and meta-analysis of early aortic valve replacement versus conservative therapy in patients with asymptomatic aortic valve stenosis with preserved left ventricle systolic function
Open Heart
JANUARY 8, 2024
Background A quarter of patients with severe aortic stenosis (AS) were asymptomatic, and only a third of them survived at the end of 4 years. Only a select subset of these patients was recommended for aortic valve replacement (AVR) by the current American College of Cardiology/American Heart Association guidelines.
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Abbott Announces First Procedures in ENVISION Trial of Navitor TAVI System to Treat Patients With Severe Aortic Stenosis
DAIC
MARCH 25, 2024
The global, randomized trial ( envisiontrial.com ) will evaluate the safety and effectiveness of Abbott’s minimally invasive Navitor transcatheter aortic valve implantation (TAVI) system in approximately 1,500 patients at intermediate or low surgical risk with severe aortic stenosis (narrowing of the aortic valve).
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Early extubation after elective surgical aortic valve replacement during the COVID-19 pandemic
Journal of Cardiothoracic Surgery
AUGUST 23, 2024
Surgical aortic valve replacement (SAVR) is an established therapy for severe calcific aortic stenosis. Enhanced recovery after cardiac surgery (ERACS) protocols have been shown to improve outcomes for electiv.
Aortic valve 52
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Eccentricity Index in Bicuspid Aortic Valve
All About Cardiovascular System and Disorders
APRIL 1, 2024
Transcript of the video: Closure line of aortic valve on M-Mode echocardiogram, is seen as central line, while in bicuspid aortic valve, it is an eccentric closure, nearer to one of the walls of the aorta. That is an important feature of bicuspid aortic valve on M-Mode echocardiogram. This is a closure line.
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The Changing Landscape of Aortic-Valve Stenosis Management
The New England Journal of Medicine
NOVEMBER 22, 2023
Aortic-valve stenosis is an increasingly important cause of cardiovascular disease, particularly among older adults, with an overall prevalence of 2.8% 1 Aortic stenosis is a progressive disease in which the rate of change of the aortic-valve area is estimated to be.
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A Y-incision to enlarge the aortic root for aortic valve stenosis with anomalous aortic origin of the right coronary artery
Journal of Cardiothoracic Surgery
FEBRUARY 3, 2024
Anomalous aortic origin of the coronary artery (AAOCA) is a rare congenital heart disease. Therefore, optimal indications for surgery in patients with severe aortic valve stenosis (AS) complicated by AAOCA rem.
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Totally 3D endoscopic aortic valve replacement: initial results and experience from a single center
Frontiers in Cardiovascular Medicine
OCTOBER 8, 2024
Patient selection was based on the presence of isolated aortic valve disease without the need for ascending aorta replacement or aortic root enlargement. The majority of patients (77.1%) presented with aortic stenosis, often accompanied by severe calcification. years, with 22.9% being female.
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Randomised study for the Optimal Treatment of symptomatic patients with low-gradient severe Aortic valve Stenosis and preserved left ventricular ejection fraction (ROTAS trial)
Heart BMJ
SEPTEMBER 25, 2024
Background The best management of symptomatic patients with low-gradient (LG) severe aortic stenosis (AS) and preserved left ventricular ejection fraction (LVEF) has not been established. The primary endpoint was a composite of overall death and/or cardiovascular hospitalisation.
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Perceval sutureless bioprosthesis versus Perimount sutured bioprosthesis for aortic valve replacement in patients with aortic stenosis: a retrospective, propensity-matched study
Journal of Cardiothoracic Surgery
FEBRUARY 13, 2024
Rapid-deployment aortic valve replacement (RDAVR) is an alternative to conventional AVR (cAVR) for aortic stenosis. Benefits include a reduction in operative times, facilitation of minimal access surgery and s.
Aortic valve 52
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Right anterior thoracotomy vs. upper hemisternotomy for aortic valve replacement with Perceval S: is there a difference?
Frontiers in Cardiovascular Medicine
OCTOBER 24, 2024
ConclusionAortic valve replacement with the Perceval S valve through either an upper hemisternotomy or a right anterior thoracotomy is a procedure associated with low perioperative complication rates. This was a retrospective, single-center observational study. ResultsThe overall in-hospital mortality was 1,7%.
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“One-stop” interventional therapy for quadricuspid aortic valve combined with severe coronary artery disease: a case report
Journal of Cardiothoracic Surgery
SEPTEMBER 11, 2024
Congenital Quadricuspid Aortic Valve (QAV) malformation is a relatively rare cardiac valve malformation, especially with abnormal coronary opening and severe stenosis of Coronary Artery Disease (CAD). The pati.
Features and Prognosis of High-Gradient Aortic Stenosis
American College of Cardiology
SEPTEMBER 24, 2024
What are the clinical features and prognosis of patients with high-gradient (HG) aortic stenosis (AS) with a calculated aortic valve area (AVA) of >1.0
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Lp(a) and Calcific Aortic Valve Stenosis Progression
American College of Cardiology
JULY 23, 2024
What is the association between plasma lipoprotein(a) [Lp(a)] concentrations and hemodynamic progression in patients with aortic stenosis?
Stenosis 56
56 
Towards a gender-specific and morphology-specific assessment of aortic valve stenosis severity
Heart BMJ
MARCH 22, 2024
Over the last two decades, the differentiation of severe from non-severe aortic valve stenosis with echocardiography has become more complex. The consideration of flow is now frequently essential to evaluate haemodynamic stenosis severity. Low flow can result in low gradient and, thereby, mask severe aortic stenosis.
Aortic valve 40
40 Abstract 4119619: Congruency of Stated Aortic Stenosis Severity and Reported Doppler Exam Values in a Large Health Care System Based on ACC/ASE Guidelines
Circulation
NOVEMBER 11, 2024
Background:Peak aortic valve Doppler velocity, mean aortic valve gradient, and Doppler estimated aortic valve area are key measures recommended for assessing aortic stenosis severity. Failure to accurately diagnose severe aortic stenosis is critical.
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40 
Abstract 4142104: Ischemic Stroke and TIA Incidence in Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement: A Comparative Systematic Review and Meta-analysis
Circulation
NOVEMBER 11, 2024
Objective:This systematic review and meta-analysis aimed to compare the incidence of ischemic stroke and Transient ischemic attack (TIA) post-transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in intermediate or high surgical risk patients with aortic stenosis, as this assessment may influence the choice of intervention.Methods:In (..)
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Medtronic Announces FDA Approval of Newest-generation Evolut TAVR System for Treatment of Symptomatic Severe Aortic Stenosis
DAIC
MARCH 28, 2024
milla1cf Thu, 03/28/2024 - 07:30 March 28, 2024 — Medtronic plc, a global leader in healthcare technology, announced that the United States Food and Drug Administration ( FDA ) has approved the Evolut FX+ transcatheter aortic valve replacement (TAVR) system for the treatment of symptomatic severe aortic stenosis.
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TAVR or SAVR in Severe Aortic Stenosis and Small Aortic Annulus
American College of Cardiology
MARCH 6, 2024
What are the hemodynamic and clinical outcomes after transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis (AS) and a small aortic annulus?
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