Circulation

JANUARY 23, 2024

Circulation, Ahead of Print. BACKGROUND:Calcification of the aortic valve leads to increased leaflet stiffness and consequently results in the development of calcific aortic valve disease (CAVD). However, the underlying molecular and cellular mechanisms of calcification remain unclear.

Aortic valve 45

Aortic valve Aortic Diet Cholesterol 45

Circulation: Cardiovascular Interventions

OCTOBER 17, 2023

Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Data concerning the outcomes of transcatheter aortic valve replacement in type 0 bicuspid aortic stenosis (AS) are scarce. Self-expanding transcatheter heart valves were used in the majority of patients (n=1160; 91.4%). Poverall=0.765; 1 year: 1.4%

Aortic valve 40

Aortic valve Bicuspid/Mitral Aortic Tricuspid 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4138340-A4138340, November 12, 2024. Background:Calcific Aortic Valve Disease is a common cardiac condition with no effective medication available; severe cases require surgery. Immunohistochemical staining showed high expression of Cav-1 in calcified aortic valves.

Aortic valve 40

Aortic valve Aortic Circulation 40

Circulation: Cardiovascular Interventions

NOVEMBER 20, 2023

Circulation: Cardiovascular Interventions, Volume 16, Issue 11 , Page e012966, November 1, 2023. Transcatheter aortic valve replacement (TAVR) is increasingly being performed in younger and lower surgical risk patients.

Aortic valve 40

Aortic valve Aortic TAVR Heart Valves 40

Circulation

OCTOBER 23, 2024

Circulation, Ahead of Print. The groups were stratified by aortic valve morphology (BAV, n=589; TAV, n=558). The outcomes of interests were new-onset third-degree AV block or new-onset LBBB during the index hospitalization.

Aortic valve 40

Aortic valve Bicuspid/Mitral Aortic Tricuspid 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142104-A4142104, November 12, 2024.

Aortic valve 40

Aortic valve Aortic TAVR Strokes 40

Circulation: Cardiovascular Imaging

DECEMBER 4, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 12 , Page e017425, December 1, 2024. BACKGROUND:In aortic stenosis, the myocardium responds with left ventricular hypertrophy, which is characterized by increased left ventricular mass due to cellular hypertrophy and extracellular matrix expansion. weeks post-AVR. weeks post-AVR.

Aortic valve 40

Aortic valve Aortic Stenosis Cardiovascular Imaging 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142998-A4142998, November 12, 2024. Introduction:Subclinical leaflet thrombosis is an increasingly recognized complication in patients undergoing transcatheter aortic valve replacement (TAVR).

Aortic valve 40

Aortic valve Thrombosis Aortic TAVR 40

Circulation

NOVEMBER 29, 2023

Circulation, Ahead of Print. BACKGROUND:A better understanding of the molecular mechanism of aortic valve development and bicuspid aortic valve (BAV) formation would significantly improve and optimize the therapeutic strategy for BAV treatment.

Aortic valve 40

Aortic valve Bicuspid/Mitral Aortic Circulation 40

Heart BMJ

MARCH 22, 2024

Objectives This study aimed to evaluate the prognostic value of coronary microvascular dysfunction (CMD) at long term after transcatheter aortic valve implantation (TAVI) and to explore its relationship with extravalvular cardiac damage (EVCD). CMD was defined as IMR angio ≥30 units.

Aortic valve 40

Aortic valve Aortic Tricuspid Heart Failure 40

Circulation

OCTOBER 25, 2023

Circulation, Ahead of Print. Background:The optimal treatment in patients with severe aortic stenosis (AS) and small aortic annulus (SAA) remains to be determined. Clinical events were secondary outcomes.Results:The mean age of the participants was 75±5 years, with 140 (93%) women, a median STS of 2.50 (1.67-3.28)%,

Aortic valve 40

Aortic valve Aortic TAVR Stenosis 40

Circulation

AUGUST 12, 2024

Circulation, Ahead of Print. Pathogeneses include connective tissue disorders, smooth muscle contraction disorders, and congenital heart disease, including bicuspid aortic valve, among others. The American Heart Association has published guidelines for diagnosis and management of thoracic aortic disease.

Pediatrics 81

Pediatrics Congenital Heart Disease Aortic valve Bicuspid/Mitral 81

American College of Cardiology

JUNE 24, 2024

Greater adverse events were associated with both low and high postprocedural aortic valve mean gradient extremes following transcatheter aortic valve implantation (TAVI) for degenerated surgical aortic valve replacement (SAVR) bioprostheses, indicating a complex and nonlinear relationship between gradients and clinical outcomes, according to a recent (..)

Aortic valve 46

Aortic valve Aortic Cardiovascular Interventions Circulation 46

Circulation: Cardiovascular Interventions

JANUARY 18, 2024

Circulation: Cardiovascular Interventions, Ahead of Print. Background:Frailty associates with worse outcomes after transcatheter aortic valve replacement (TAVR). Cross-sectional muscle (psoas and paraspinal) areas were measured on computed tomography and indexed to height. per 1 SD decrease [95% CI, 1.15–1.89];P=0.002)

Aortic valve 40

Aortic valve Aortic TAVR Stenosis 40

Circulation: Cardiovascular Interventions

OCTOBER 22, 2023

Circulation: Cardiovascular Interventions, Ahead of Print. Background:Atherosclerotic cardiovascular disease (ASCVD) is highly prevalent in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR).

Aortic valve 40

Aortic valve Aortic TAVR Outcomes 40

Circulation: Cardiovascular Interventions

NOVEMBER 20, 2023

Circulation: Cardiovascular Interventions, Volume 16, Issue 11 , Page e013305, November 1, 2023.

Aortic valve 40

Aortic valve Aortic Cardiovascular Interventions Circulation 40

Circulation

JUNE 17, 2024

Circulation, Ahead of Print. Severe disease is managed with valve replacement procedures, which entail high health care–related costs and postprocedural morbidity and mortality. Valvular heart disease is a common cause of morbidity and mortality worldwide and has no effective medical therapy.

Bicuspid/Mitral 65

Bicuspid/Mitral Heart Disease Aortic valve Heart Valves 65

Circulation

OCTOBER 23, 2023

Circulation, Ahead of Print. Background: Atrial fibrillation (AF) is common in patients undergoing transcatheter aortic valve replacement (TAVR) and is associated with increased risk of bleeding and stroke. For the composite primary endpoint, TAVR+.LAAO LAAO was non-inferior to TAVR+ medical therapy (22.7

Aortic valve 40

Aortic valve Atrial Fibrillation TAVR Aortic 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4119619-A4119619, November 12, 2024. Background:Peak aortic valve Doppler velocity, mean aortic valve gradient, and Doppler estimated aortic valve area are key measures recommended for assessing aortic stenosis severity.

Stenosis 40

Stenosis Aortic valve Aortic Echocardiogram 40

DAIC

FEBRUARY 3, 2025

Lp(a) is emerging as an important, yet under-recognized, potential risk factor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. Circulation. 2022 Aug, 80 (9) 934946 Kronenberg F. Arnett DK et al. 2019 Sep 10;140(11):e563-e595.

Cardiovascular Disease 52

Cardiovascular Disease Aortic valve Innovation Biomarkers 52

Circulation: Cardiovascular Imaging

JANUARY 8, 2025

Circulation: Cardiovascular Imaging, Ahead of Print.

Aortic valve 40

Aortic valve Aortic Cardiovascular Imaging Stenosis 40

Circulation: Cardiovascular Quality & Outcomes

DECEMBER 13, 2023

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

TAVR 40

TAVR Aortic valve Aortic Outcomes 40

Circulation: Cardiovascular Interventions

NOVEMBER 20, 2023

Circulation: Cardiovascular Interventions, Volume 16, Issue 11 , Page e013497, November 1, 2023.

Aortic valve 40

Aortic valve Aortic Anatomy Cardiovascular Interventions 40

Circulation: Cardiovascular Imaging

FEBRUARY 5, 2025

Circulation: Cardiovascular Imaging, Ahead of Print.

Bicuspid/Mitral 40

Bicuspid/Mitral Aortic valve Cardiovascular Imaging Aortic 40

Circulation: Cardiovascular Imaging

DECEMBER 4, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 12 , Page e017716, December 1, 2024.

Aortic valve 40

Aortic valve Cardiovascular Imaging Aortic Circulation 40

Circulation: Cardiovascular Interventions

NOVEMBER 20, 2023

Circulation: Cardiovascular Interventions, Volume 16, Issue 11 , Page e013296, November 1, 2023. BACKGROUND:Redo transcatheter aortic valve implantation (TAVI) is increasing as patients outlive their transcatheter heart valves (THVs) and present with bioprosthetic valve failure.

Aortic valve 40

Aortic valve Heart Valves Aortic Cardiovascular Interventions 40

Open Heart

MARCH 24, 2023

Our perspectives on aortic stenosis (AS) are changing. Novel approaches are developing to address this through: (1) screening with circulating biomarkers; (2) development of drugs to slow disease progression and (3) early valve intervention guided by medical imaging. Currently, invasive intervention is the only treatment for AS.

Stenosis 52

Stenosis Aortic Aortic valve Biomarkers 52

Circulation: Heart Failure

SEPTEMBER 28, 2023

Circulation: Heart Failure, Ahead of Print.

Aortic valve 40

Aortic valve Aortic Heart Failure Circulation 40

Circulation: Cardiovascular Interventions

NOVEMBER 20, 2023

Circulation: Cardiovascular Interventions, Volume 16, Issue 11 , Page e013571, November 1, 2023.

Aortic valve 40

Aortic valve TAVR Cardiovascular Interventions Aortic 40

Circulation: Cardiovascular Imaging

JANUARY 17, 2025

Circulation: Cardiovascular Imaging, Ahead of Print.

Aortic valve 40

Aortic valve Thrombosis Cardiovascular Imaging Aortic 40

Circulation: Cardiovascular Imaging

DECEMBER 21, 2023

Circulation: Cardiovascular Imaging, Ahead of Print.

Aortic valve 40

Aortic valve Cardiovascular Imaging Aortic Circulation 40

Circulation: Cardiovascular Interventions

NOVEMBER 9, 2023

Circulation: Cardiovascular Interventions, Ahead of Print.

Aortic valve 40

Aortic valve Aortic Cardiovascular Interventions Stenosis 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4148073-A4148073, November 12, 2024. Case Description:A 26 yo woman with Marfan Syndrome (MFS,FBN1), ectopia lentis, aortic dilation and no family history of MFS or aortic dissection was evaluated for preconception counseling. Our patient’s pathogenicFBN1mutation (-c.2114-5T>G,

Aortic 40

Aortic Aortic valve Education Circulation 40

All About Cardiovascular System and Disorders

MARCH 30, 2024

Transcript of video: Hypoplastic Left Heart Syndrome is a very severe form of congenital heart disease, in which, the left ventricle, aorta and mitral and aortic valves are hypoplastic and valves may be atretic as well. So right ventricle maintains both systemic and pulmonary circulation after a Norwood procedure.

Aortic valve 52

Aortic valve Pulmonary Congenital Heart Disease Bicuspid/Mitral 52

Circulation: Cardiovascular Interventions

NOVEMBER 25, 2024

Circulation: Cardiovascular Interventions, Volume 17, Issue 12 , Page e014696, December 1, 2024.

Aortic valve 40

Aortic valve Cardiovascular Interventions Aortic Circulation 40

Circulation: Cardiovascular Interventions

JANUARY 24, 2025

Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Transcatheter heart valve (THV) underexpansion after transcatheter aortic valve replacement may be associated with worse outcomes.

Heart Valves 40

Heart Valves Aortic valve TAVR Aortic 40

Circulation: Cardiovascular Interventions

DECEMBER 4, 2023

Circulation: Cardiovascular Interventions, Ahead of Print.

Aortic valve 40

Aortic valve Heart Valves Cardiovascular Interventions Aortic 40