Heart BMJ

FEBRUARY 12, 2025

Background Bicuspid aortic valve (BAV) is the most common congenital heart defect in adults, often leading to complications such as thoracic aortic aneurysms and aortic stenosis. While BAV is frequently associated with 22q11.2 This study is aimed to assess the role of rare 22q11.2 region (18–24 Mb).

Aortic valve 52

Aortic valve Bicuspid/Mitral Aortic Aneurysm 52

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2025

Small aortic annulus poses a major challenge in aortic valve replacement due to the increased risk of prosthesispatient mismatch (PPM) and increased surgical risk. In recent years, transcatheter aortic valve replacement (TAVR) has emerged as a popular alternative to the traditional surgical aortic valve replacement.

Aortic valve 52

Aortic valve Aortic TAVR Myocardial Infarction 52

JAMA Cardiology

FEBRUARY 11, 2025

This Viewpoint advocates for prompt aortic valve replacement (rather than clinical surveillance) as the default strategy for patients with asymptomatic severe aortic stenosis.

Aortic valve 95

Aortic valve Aortic Stenosis 95

Journal of Cardiothoracic Surgery

FEBRUARY 4, 2025

Studies were excluded if they weren’t exclusively conducted on patients submitted to surgical aortic valve replacement using the Inspiris Resilia bioprosthesis. Its performance appears to be equal to or better than many other bioprosthetic valves. Results The technical success rate was almost perfect in all studies.

Aortic valve 52

Aortic valve Aortic Outcomes Article 52

JAMA Cardiology

OCTOBER 15, 2024

This narrative review analyzes associations among heart failure, aortic stenosis, and aortic valve replacement.

Aortic valve 92

Aortic valve Heart Failure Aortic Stenosis 92

Frontiers in Cardiovascular Medicine

MARCH 20, 2025

ObjectivesRegistered, prospective, multicenter study of the short-term clinical outcomes of a novel transcatheter aortic valve system (Xcor system, Saint Medical Technology, Inc.,

Aortic valve 52

Aortic valve Aortic Bicuspid/Mitral Stenosis 52

Medical Xpress - Cardiology

SEPTEMBER 2, 2024

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

Aortic valve 105

Aortic valve Bicuspid/Mitral Aortic Research 105

Med Page Today

JANUARY 26, 2025

(MedPage Today) -- LOS ANGELES -- Survival outcomes favored mechanical valves for isolated surgical aortic valve replacement (SAVR) for people until age 60, after which a tissue valve may start to have an advantage, according to a large registry.

Aortic valve 105

Aortic valve Aortic Outcomes 105

Heart BMJ

JANUARY 29, 2025

Background Subclinical leaflet thrombosis (SLT) is a common complication after transcatheter aortic valve replacement (TAVR). Methods This prospective cohort study consecutively enrolled patients with severe symptomatic aortic stenosis who underwent successful TAVR.

Aortic valve 52

Aortic valve Thrombosis Aortic Technology 52

Heart BMJ

JULY 10, 2024

Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).

Aortic valve 98

Aortic valve Aortic Quality of Life TAVR 98

DAIC

DECEMBER 12, 2023

milla1cf Tue, 12/12/2023 - 07:00 December 12, 2023 — Patients who received the anticoagulant drug warfarin after bioprosthetic aortic valve replacement had lower incidence of mortality and a decreased risk of blood clots, according to a retrospective study published in Mayo Clinic Proceedings.

Aortic valve 116

Aortic valve Aortic Blood Clot Medicare 116

Frontiers in Cardiovascular Medicine

AUGUST 7, 2024

Aortic Stenosis (AS) is a common condition with an estimated pooled prevalence of all AS in the elderly population at around 12.4%, with that of severe AS estimated to be around 3.4%. In the past, surgical aortic valve replacement was the primary treatment option for severe AS for decades.

Aortic valve 98

Aortic valve Aortic TAVR Peripheral Arterial Disease 98

JAMA Cardiology

AUGUST 13, 2024

This randomized clinical trial evaluates the safety and efficacy of administration of protamine to reduce bleeding following transcatheter aortic valve implantation vs placebo, selective protamine administration.

Aortic valve 89

Aortic valve Aortic 89

Society of Thoracic Surgeons - Adult Cardiac

JANUARY 26, 2025

Shettys team followed 252 patients who underwent the Ross procedure, a heart valve replacement operation commonly used to treat younger patients with severe aortic valve disease. Freedom from aortic regurgitation was 95.1%, 92.2%, 87.7%, and 84.5% Shettys team found that survival rates were 95.8% at 5 years, 94.3%

Aortic valve 83

Aortic valve Cardiothoracic Congenital Aortic 83

DAIC

JANUARY 29, 2024

Getty Images milla1cf Mon, 01/29/2024 - 14:24 January 29, 2024 — Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis , many hospitals are still opting for a nonsurgical approach in patients under 60—possibly with poorer survival rates.

Aortic valve 111

Aortic valve TAVR Aortic Outcomes 111

Science Daily - Heart Disease

JANUARY 15, 2025

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease.

Aortic valve 86

Aortic valve Bicuspid/Mitral Aortic 86

American College of Cardiology

MAY 24, 2024

What is the relationship between aortic valve calcification (AVC) and aortic stenosis (AS) severity in patients with suspected low-flow low-gradient AS?

Aortic valve 70

Aortic valve Aortic Stenosis Article 70

Frontiers in Cardiovascular Medicine

FEBRUARY 17, 2025

IntroductionSince TAVR was approved for lower-risk aortic stenosis (AS) patients, managing post-implantation conduction disturbances has become crucial, especially with self-expanding heart valves (SEV).

Pacemaker 52

Pacemaker Aortic Stenosis Aortic valve 52

Med Page Today

OCTOBER 28, 2024

(MedPage Today) -- Transcatheter aortic valve replacement (TAVR) yielded clinical benefit when given early in the disease process while patients still had no symptoms or other indication for aortic valve replacement, according to the EARLY TAVR.

TAVR 105

TAVR Aortic Aortic valve Stenosis 105

Heart BMJ

FEBRUARY 26, 2025

A significant proportion of patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) have concomitant coronary artery disease (CAD). The best way to treat these patients is contentious.

Coronary Artery Disease 59

Coronary Artery Disease Stenosis Aortic Aortic valve 59

Frontiers in Cardiovascular Medicine

JANUARY 30, 2025

Bileaflet mechanical heart valves (MHV) remain a viable option for aortic valve replacement, particularly for younger patients and patients from low- and middle-income countries and underserved communities. Despite their exceptional durability, MHV recipients are at increased risk of thromboembolic complications.

Heart Valves 52

Heart Valves Aortic Aortic valve Blood Clot 52

Open Heart

JANUARY 19, 2025

Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. Aim This study aimed to systematically review and analyse the existing evidence on outcomes of emergency transcatheter aortic valve implantation (eTAVI) and emergency balloon aortic valvuloplasty (eBAV) in CS patients.

Cardiogenic Shock 52

Cardiogenic Shock Aortic Stenosis Aortic valve 52

Open Heart

FEBRUARY 27, 2024

Objectives The clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with aortic stenosis (AS) and concomitant active cancer remain insufficiently explored. This study aimed to assess the midterm outcomes of TAVR in patients diagnosed with AS and active cancer.

Aortic valve 98

Aortic valve Cancer Aortic TAVR 98

JAMA Cardiology

MAY 14, 2024

This cohort study examines whether there is an association between osteosarcopenia and adverse outcomes, such as increased risk of mortality, in older adults following transcatheter aortic valve replacement (TAVR).

Aortic valve 73

Aortic valve Aortic TAVR Outcomes 73

Journal of Cardiothoracic Surgery

MARCH 25, 2025

Quadricuspid aortic valve (QAV) is rare. However, to repair a quadricuspid aortic valve is not as easy to realize as in bicuspid aortic valve. The surgical design is crucial to rebuild the stable structure.

Aortic valve 52

Aortic valve Aortic Bicuspid/Mitral Tricuspid 52

JAMA Cardiology

OCTOBER 29, 2024

This cohort study assesses characteristics and outcomes of younger patients undergoing transcatheter aortic valve replacement.

Aortic valve 65

Aortic valve Aortic Outcomes 65

Science Daily - Heart Disease

JUNE 5, 2024

Researchers have now proposed a molecular mechanism that links amyloid deposition in the aortic valve with degenerative calcification.

Aortic valve 68

Aortic valve Aortic Risk Factors Research 68

Frontiers in Cardiovascular Medicine

JANUARY 19, 2025

The co-occurrence of a bicuspid aortic valve (BAV) with TSC is exceedingly rare.Case summaryWe report the case of a 26-year-old woman with genetically confirmed TSC, harboring a novel pathogenic variant in the TSC2 gene. multi-system characteristics of TSC were also presented, affecting skin, brain, lung, kidney, and bone.

Aortic valve 52

Aortic valve Bicuspid/Mitral Aortic Heart Valves 52

DAIC

MARCH 25, 2024

The global, randomized trial ( envisiontrial.com ) will evaluate the safety and effectiveness of Abbott’s minimally invasive Navitor transcatheter aortic valve implantation (TAVI) system in approximately 1,500 patients at intermediate or low surgical risk with severe aortic stenosis (narrowing of the aortic valve).

Stenosis 115

Stenosis Aortic Aortic valve Heart Valves 115

American College of Cardiology

SEPTEMBER 18, 2024

The goal of the AVATAR trial was to evaluate aortic valve replacement (AVR) compared with conservative therapy among patients with asymptomatic severe aortic stenosis.

Aortic valve 57

Aortic valve Aortic Stenosis Article 57

Heart BMJ

FEBRUARY 26, 2025

In the 22 years since Professor Alain Cribier performed the first transcatheter aortic valve implantation (TAVI) in Rouen in France, treatment pathways for patients with aortic valve stenosis have evolved rapidly.

Aortic valve 59

Aortic valve Aortic Stenosis 59

Heart BMJ

JUNE 25, 2024

A transthoracic echocardiogram (TTE) revealed a mobile mass on the right coronary cusp of the aortic valve ( figure 1 , ). cm) at the right coronary cusp of the aortic valve on the long-axis and short-axis parasternal view. Figure 1 A mobile mass (1.88 Question What is the most likely diagnosis?

Aortic valve 59

Aortic valve Aortic Chest Pain Atrial Fibrillation 59

Frontiers in Cardiovascular Medicine

FEBRUARY 20, 2024

Background Closure of paravalvular leak (PVL) regurgitation after self-expandable (SE) transcatheter aortic valve implantation (TAVI) may be more challenging than after balloon-expandable (BE) valve implantation. MN, USA).

Aortic valve 111

Aortic valve Aortic Atrial Fibrillation Heart Failure 111

Frontiers in Cardiovascular Medicine

FEBRUARY 6, 2025

IntroductionClinical evidence highlighting the efficacy and safety of transcatheter aortic valve replacement (TAVR) and the 2019 Food and Drug Administration (FDA) approval for TAVR in low-risk (younger) patients has created a demand for durable and long-lasting bioprosthetic heart valve (BHV) leaflet materials.

Heart Valves 52

Heart Valves Aortic TAVR Aortic valve 52

JAMA Cardiology

JULY 16, 2024

This meta-analysis evaluates lipoprotein(a) concentrations and hemodynamic progression in patients with aortic stenosis.

Stenosis 79

Stenosis Aortic valve Aortic 79

Society of Thoracic Surgeons - Congenital

JANUARY 8, 2025

News Increased Risk of Surgical Aortic Valve Replacement After Prior Transcatheter vs. Surgical Aortic Valve Replacement with Concomitant Valve Disease pvaldez Wed, 01/08/2025 - 09:50 2 min read

Aortic valve 52

Aortic valve Aortic 52

Heart BMJ

MARCH 26, 2025

Heart failure (HF) is one of the significant complications in patients with myocardial infarction (MI), leading to increased risk for cardiovascular morbidity and mortality. 2 However, mortality rate is greater in HF cases developing >3 days following MI compared with less than or equal to 3 days after MI.

Myocardial Infarction 52

Myocardial Infarction Preserved Ejection Fraction Heart Failure Aortic valve 52