Aortic Stenosis, Heart Failure, and Aortic Valve Replacement
JAMA Cardiology
OCTOBER 15, 2024
This narrative review analyzes associations among heart failure, aortic stenosis, and aortic valve replacement.
Management of bicuspid aortic valve disease in the transcatheter aortic valve implantation era
Heart BMJ
OCTOBER 28, 2024
In an era of rapidly expanding use of transcatheter aortic valve implantation (TAVI), the management of patients with bicuspid aortic valve (BAV) disease is far less well established than in those with trileaflet anatomy.
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Rare genetic variants linked to bicuspid aortic valve disease in young adults identified
Medical Xpress - Cardiology
SEPTEMBER 2, 2024
Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.
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105 Routine Protamine Administration for Bleeding in Transcatheter Aortic Valve Implantation
JAMA Cardiology
AUGUST 13, 2024
This randomized clinical trial evaluates the safety and efficacy of administration of protamine to reduce bleeding following transcatheter aortic valve implantation vs placebo, selective protamine administration.
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TAVI Matches SAVR in Lower Risk Aortic Valve Patients: 10 year outcomes
Cardiology Update
FEBRUARY 11, 2024
The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk.
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Sarcopenia and aortic valve disease
Heart BMJ
JULY 10, 2024
Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).
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New Study Suggests that Amyloid Contributes to Calcific Aortic Valve Disease Development
DAIC
JUNE 7, 2024
Getty Images milla1cf Fri, 06/07/2024 - 15:10 June 7, 2024 — Calcific aortic valve disease (CAVD) is the major heart valve disease that afflicts nearly 10 million patients globally with an annual mortality exceeding 100,000, and the numbers continue to rise.
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Alternative access in transcatheter aortic valve replacement—an updated focused review
Frontiers in Cardiovascular Medicine
AUGUST 7, 2024
Aortic Stenosis (AS) is a common condition with an estimated pooled prevalence of all AS in the elderly population at around 12.4%, with that of severe AS estimated to be around 3.4%. In the past, surgical aortic valve replacement was the primary treatment option for severe AS for decades.
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Aortic Valve ReplAcemenT versus Conservative Treatment in Asymptomatic SeveRe Aortic Stenosis
American College of Cardiology
SEPTEMBER 18, 2024
The goal of the AVATAR trial was to evaluate aortic valve replacement (AVR) compared with conservative therapy among patients with asymptomatic severe aortic stenosis.
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Cardiawave Releases Positive Data on Non-Invasive Valvosoft Aortic Valve Therapy
DAIC
NOVEMBER 7, 2024
28, 2024 — Cardiawave SA, developer of Valvosoft Non-Invasive Ultrasound Therapy (NIUT) device for treating severe symptomatic calcific aortic stenosis (CAS), announced that the device met the primary endpoint in its pivotal study and improved or stabilized heart failure symptoms for 80.5 tim.hodson Thu, 11/07/2024 - 10:19 Oct. 113–116, Mar.
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59 Dedicated trial in women demonstrates the superiority of transcatheter vs. surgical aortic valve replacement
Medical Xpress - Cardiology
SEPTEMBER 3, 2024
Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.
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Aortic Valve Calcification in Low-Gradient Aortic Stenosis
American College of Cardiology
MAY 24, 2024
What is the relationship between aortic valve calcification (AVC) and aortic stenosis (AS) severity in patients with suspected low-flow low-gradient AS?
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Abstract 4145296: Aortic Valve Hemodynamics in Liver Cirrhosis
Circulation
NOVEMBER 11, 2024
Aortic valve stenosis (AS) is often a contraindication to liver transplantation (LT). Despite the widely accepted impact of liver cirrhosis on aortic valve hemodynamics, the change in these parameters with LT or impact of AS on LT outcomes has not been described. m/s, p < 0.001) as compared to mild AS (1.5
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Researchers ID Genetic Variants Linked to Bicuspid Aortic Valve Disease
DAIC
SEPTEMBER 4, 2024
1, 2024 — Researchers at UTHealth Houston have identified genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications. tim.hodson Wed, 09/04/2024 - 15:53 Sept.
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Later aorta operation after aortic valve replacement for bicuspid aortic valve
Journal of Cardiothoracic Surgery
MARCH 18, 2024
We investigated long-term outcomes, particularly later aorta operations and overall death in patients who underwent aortic valve replacement for bicuspid aortic valve without aortic surgery.
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Third Nordic Aortic Valve Intervention
American College of Cardiology
AUGUST 31, 2024
The goal of the NOTION-3 trial was to evaluate percutaneous coronary intervention (PCI) compared with conservative therapy among patients with obstructive coronary artery disease undergoing transcatheter aortic valve implantation (TAVI).
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Fungal endocarditis after transcatheter aortic valve implantation complicated with pseudoaneurysm of the ascending aorta
Journal of Cardiothoracic Surgery
NOVEMBER 5, 2024
Fungal endocarditis following transcatheter aortic valve implantation (TAVI) is a rare and serious complication of this procedure. We describe a case of a 75-year-old patient who developed fungal endocarditis.
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52 Abstract 4138340: Cav-1/FGF2 Axis Mediates Endothelial-Mesenchymal Transition Promoting Aortic Valve Calcification
Circulation
NOVEMBER 11, 2024
Background:Calcific Aortic Valve Disease is a common cardiac condition with no effective medication available; severe cases require surgery. Single-cell RNA sequencing on 3 calcified aortic valves focused on valve endothelial and interstitial cells to explore key genes and functions in EndoMT.
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The neo-aortic valve in patients with hypoplastic left heart syndrome is largely preserved: a serial follow-up CMR study
Frontiers in Cardiovascular Medicine
NOVEMBER 5, 2024
BackgroundIn hypoplastic left heart syndrome (HLHS) patients, neo-aortic valve regurgitation can negatively impact right ventricular (RV) function. None of the patients had significant neo-aortic valve stenosis (peak velocity >3 m/s). RF correlated with RVESVi and RVEF at the second examination.
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Surgical management of native aortic valve leaflet avulsion during TAVR
Journal of Cardiothoracic Surgery
JULY 29, 2024
Transcatheter aortic valve replacement (TAVR) has increased in utilization since its approval for management of aortic stenosis patients across all risk strata. We report a rare case of aortic valve leaflet av.
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Eccentricity Index in Bicuspid Aortic Valve
All About Cardiovascular System and Disorders
APRIL 1, 2024
Transcript of the video: Closure line of aortic valve on M-Mode echocardiogram, is seen as central line, while in bicuspid aortic valve, it is an eccentric closure, nearer to one of the walls of the aorta. That is an important feature of bicuspid aortic valve on M-Mode echocardiogram. This is a closure line.
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Major Win for Preemptive TAVR in Symptomless Aortic Stenosis
Med Page Today
OCTOBER 28, 2024
(MedPage Today) -- Transcatheter aortic valve replacement (TAVR) yielded clinical benefit when given early in the disease process while patients still had no symptoms or other indication for aortic valve replacement, according to the EARLY TAVR.
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Transcatheter aortic valve replacement in patients with systolic heart failure, aortic stenosis shows limited benefits
Medical Xpress - Cardiology
OCTOBER 29, 2024
Findings from the TAVR UNLOAD study found limited benefits of transcatheter aortic valve replacement (TAVR) in the treatment of heart failure (HF) with reduced ejection fraction (HFrEF) and moderate aortic stenosis (AS).
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Nordic Aortic Valve Intervention
American College of Cardiology
FEBRUARY 12, 2024
The goal of the NOTION trial was to compare outcomes after transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) in unselected patients with severe degenerative aortic stenosis.
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55 Outcomes of Balloon-Expandable Transcatheter Aortic Valve Replacement in Younger Patients
JAMA Cardiology
OCTOBER 29, 2024
This cohort study assesses characteristics and outcomes of younger patients undergoing transcatheter aortic valve replacement.
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Cardiopulmonary exercise testing in aortic stenosis patients before and after aortic valve replacement
Open Heart
NOVEMBER 9, 2024
Background Knowledge about how patients with symptomatic aortic stenosis (AS) perform on cardiopulmonary exercise testing (CPET) is sparse. We aimed to investigate maximal and submaximal physical capacity by CPET before and 1 year after surgical aortic valve replacement (sAVR) in patients with severe AS.
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Use of Anticoagulant Drug after Aortic Valve Replacement Lowers Mortality Risk, Mayo Clinic Study Finds
DAIC
DECEMBER 12, 2023
milla1cf Tue, 12/12/2023 - 07:00 December 12, 2023 — Patients who received the anticoagulant drug warfarin after bioprosthetic aortic valve replacement had lower incidence of mortality and a decreased risk of blood clots, according to a retrospective study published in Mayo Clinic Proceedings.
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Unexpected finding on imaging: an aortic valve mass
Heart BMJ
JUNE 25, 2024
A transthoracic echocardiogram (TTE) revealed a mobile mass on the right coronary cusp of the aortic valve ( figure 1 , ). cm) at the right coronary cusp of the aortic valve on the long-axis and short-axis parasternal view. Figure 1 A mobile mass (1.88 Question What is the most likely diagnosis?
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Osteosarcopenia and Mortality in Older Adults Undergoing Transcatheter Aortic Valve Replacement
JAMA Cardiology
MAY 14, 2024
This cohort study examines whether there is an association between osteosarcopenia and adverse outcomes, such as increased risk of mortality, in older adults following transcatheter aortic valve replacement (TAVR).
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Totally 3D endoscopic aortic valve replacement: initial results and experience from a single center
Frontiers in Cardiovascular Medicine
OCTOBER 8, 2024
Patient selection was based on the presence of isolated aortic valve disease without the need for ascending aorta replacement or aortic root enlargement. The majority of patients (77.1%) presented with aortic stenosis, often accompanied by severe calcification. years, with 22.9% being female.
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Results of the inoperable and operable with aortic valve endocarditis
Frontiers in Cardiovascular Medicine
JANUARY 15, 2024
Objectives To evaluate the results of the inoperable and operable with aortic valve endocarditis, focus on risk factors, significance, and management of destruction of the aortic annulus in aortic valve endocarditis. There were 32 operative deaths (6.3%, 32/512).
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Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in patients with ADvanced heart failure
American College of Cardiology
OCTOBER 28, 2024
The goal of the TAVR UNLOAD trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with clinical surveillance among patients with chronic systolic heart failure and moderate aortic stenosis (stage B aortic stenosis).
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Early transcatheter aortic valve replacement can be beneficial for asymptomatic severe aortic stenosis patients: Study
Medical Xpress - Cardiology
OCTOBER 29, 2024
The first powered randomized trial examining early intervention with transcatheter aortic valve replacement (TAVR) in patients with asymptomatic, severe aortic stenosis (AS) found this strategy to be both a safe and effective alternative to clinical surveillance (CS).
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Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement for Treating Elderly Patients With Severe Aortic Stenosis and Small Aortic Annuli
American College of Cardiology
APRIL 4, 2024
The goal of the VIVA trial was to evaluate transcatheter aortic valve replacement (TAVR) compared with surgical aortic valve replacement (SAVR) among patients with severe aortic stenosis and a small aortic annulus.
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Outcomes in patients with aortic stenosis and severely reduced ejection fraction following surgical aortic valve replacement and transcatheter aortic valve replacement
Journal of Cardiothoracic Surgery
APRIL 19, 2024
Patients with severe aortic stenosis (AS) and left ventricular (LV) dysfunction demonstrate improvement in left ventricular injection fraction (LVEF) after aortic valve replacement (AVR). The timing and magnit.
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Clinical Validation of the 2021 European Society of Cardiology Guidelines on Pre-existing Right Bundle Branch Block in Patients undergoing Transcatheter Aortic Valve Implantation
HeartRhythm
NOVEMBER 21, 2024
Risk stratification of patients with right bundle branch block (RBBB) undergoing transcatheter aortic valve implantation (TAVI) remains challenging.
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Right anterior thoracotomy vs. upper hemisternotomy for aortic valve replacement with Perceval S: is there a difference?
Frontiers in Cardiovascular Medicine
OCTOBER 24, 2024
ConclusionAortic valve replacement with the Perceval S valve through either an upper hemisternotomy or a right anterior thoracotomy is a procedure associated with low perioperative complication rates. This was a retrospective, single-center observational study. ResultsThe overall in-hospital mortality was 1,7%.
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Sutureless Valve Option for Aortic Valve Disease: Key Points
American College of Cardiology
JULY 16, 2024
The following are key points to remember from a state-of-the-art review on sutureless valves, a “wireless†option for patients with aortic valve disease.
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Early extubation after elective surgical aortic valve replacement during the COVID-19 pandemic
Journal of Cardiothoracic Surgery
AUGUST 23, 2024
Surgical aortic valve replacement (SAVR) is an established therapy for severe calcific aortic stenosis. Enhanced recovery after cardiac surgery (ERACS) protocols have been shown to improve outcomes for electiv.
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TAVR or SAVR for Failed Bioprosthetic Aortic Valves
American College of Cardiology
MAY 29, 2024
How do mortality and morbidity compare after valve-in-valve (ViV) transcatheter aortic valve replacement (TAVR) versus redo surgical aortic valve replacement (SAVR) for intervention for a failed bioprosthetic SAVR?
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Sub-coronary aortic root replacement post-aortic valve dehiscence: a case report
Journal of Cardiothoracic Surgery
MARCH 25, 2024
This is a case report of a 78-year-old male who underwent a sub-coronary aortic valve and root replacement due to valve dehiscence and aortic root pseudoaneurysm. The patient had complex anomalous coronary ana.
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Aortic valve perivascular adipose tissue computed tomography attenuation in patients with aortic stenosis
Heart BMJ
APRIL 15, 2024
Objective Aortic stenosis (AS) shares pathophysiological similarities with atherosclerosis including active inflammation. CT attenuation of perivascular adipose tissue provides a measure of vascular inflammation that is linked to prognosis and has the potential to be applied to the aortic valve. HU, p=0.099).
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Treatment options for isolated aortic valve insufficiency: a review
Frontiers in Cardiovascular Medicine
APRIL 10, 2024
Aortic insufficiency (AI) is a valvular disease with increasing prevalence in older patients. Traditional interventions included aortic valve replacement with either mechanical or bioprosthetic aortic valves. The modern era provides numerous options for the management of AI which is explored here.
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52 Abstract 4142104: Ischemic Stroke and TIA Incidence in Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement: A Comparative Systematic Review and Meta-analysis
Circulation
NOVEMBER 11, 2024
Objective:This systematic review and meta-analysis aimed to compare the incidence of ischemic stroke and Transient ischemic attack (TIA) post-transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in intermediate or high surgical risk patients with aortic stenosis, as this assessment may influence the choice of intervention.Methods:In (..)
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