JAMA Cardiology

OCTOBER 15, 2024

This narrative review analyzes associations among heart failure, aortic stenosis, and aortic valve replacement.

Aortic valve 110

Aortic valve Heart Failure Aortic Stenosis 110

Frontiers in Cardiovascular Medicine

MARCH 20, 2025

ObjectivesRegistered, prospective, multicenter study of the short-term clinical outcomes of a novel transcatheter aortic valve system (Xcor system, Saint Medical Technology, Inc.,

Aortic valve 52

Aortic valve Aortic Bicuspid/Mitral Stenosis 52

Frontiers in Cardiovascular Medicine

JANUARY 16, 2025

Calcific aortic valve disease (CAVD) is a common cardiovascular condition in the elderly population.

Aortic valve 52

Aortic valve Aortic Stenosis Research 52

Cardiology Update

FEBRUARY 11, 2024

The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk.

Aortic valve 124

Aortic valve Aortic Outcomes Thrombosis 124

Heart BMJ

FEBRUARY 12, 2025

Background Bicuspid aortic valve (BAV) is the most common congenital heart defect in adults, often leading to complications such as thoracic aortic aneurysms and aortic stenosis. While BAV is frequently associated with 22q11.2 This study is aimed to assess the role of rare 22q11.2 region (18–24 Mb).

Aortic valve 52

Aortic valve Bicuspid/Mitral Aortic Aneurysm 52

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2025

Small aortic annulus poses a major challenge in aortic valve replacement due to the increased risk of prosthesispatient mismatch (PPM) and increased surgical risk. In recent years, transcatheter aortic valve replacement (TAVR) has emerged as a popular alternative to the traditional surgical aortic valve replacement.

Aortic valve 52

Aortic valve Aortic TAVR Myocardial Infarction 52

Journal of Cardiothoracic Surgery

FEBRUARY 4, 2025

Studies were excluded if they weren’t exclusively conducted on patients submitted to surgical aortic valve replacement using the Inspiris Resilia bioprosthesis. Its performance appears to be equal to or better than many other bioprosthetic valves. Results The technical success rate was almost perfect in all studies.

Aortic valve 52

Aortic valve Aortic Outcomes Article 52

Frontiers in Cardiovascular Medicine

FEBRUARY 5, 2025

A 70-year-old female patient with a history of bioprosthetic aortic valve replacement and coronary artery bypass graft presented with bioprosthetic valve failure secondary to prosthetic valve endocarditis. This resulted in early death due to myocardial infarction and acute heart failure.

Aortic valve 52

Aortic valve Coronary Artery Bypass Graft Thrombosis Aortic 52

DAIC

JUNE 7, 2024

Getty Images milla1cf Fri, 06/07/2024 - 15:10 June 7, 2024 — Calcific aortic valve disease (CAVD) is the major heart valve disease that afflicts nearly 10 million patients globally with an annual mortality exceeding 100,000, and the numbers continue to rise.

Aortic valve 105

Aortic valve Aortic Heart Valves Pharmacology 105

JAMA Cardiology

AUGUST 13, 2024

This randomized clinical trial evaluates the safety and efficacy of administration of protamine to reduce bleeding following transcatheter aortic valve implantation vs placebo, selective protamine administration.

Aortic valve 101

Aortic valve Aortic 101

Medical Xpress - Cardiology

SEPTEMBER 2, 2024

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

Aortic valve 105

Aortic valve Bicuspid/Mitral Aortic Research 105

Med Page Today

JANUARY 26, 2025

(MedPage Today) -- LOS ANGELES -- Survival outcomes favored mechanical valves for isolated surgical aortic valve replacement (SAVR) for people until age 60, after which a tissue valve may start to have an advantage, according to a large registry.

Aortic valve 104

Aortic valve Aortic Outcomes 104

Heart BMJ

JANUARY 29, 2025

Background Subclinical leaflet thrombosis (SLT) is a common complication after transcatheter aortic valve replacement (TAVR). Methods This prospective cohort study consecutively enrolled patients with severe symptomatic aortic stenosis who underwent successful TAVR.

Aortic valve 52

Aortic valve Thrombosis Aortic Technology 52

Heart BMJ

JULY 10, 2024

Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).

Aortic valve 98

Aortic valve Aortic Quality of Life TAVR 98

DAIC

DECEMBER 12, 2023

milla1cf Tue, 12/12/2023 - 07:00 December 12, 2023 — Patients who received the anticoagulant drug warfarin after bioprosthetic aortic valve replacement had lower incidence of mortality and a decreased risk of blood clots, according to a retrospective study published in Mayo Clinic Proceedings.

Aortic valve 116

Aortic valve Aortic Blood Clot Medicare 116

Open Heart

MARCH 3, 2025

Background In congenital aortic stenosis (CAS), commissurotomy is an option in patients not suitable to receive a valve prosthesis. However, there is often a need for future additional interventions on the aortic valve. The fate of the aortic valve is, however, essentially unknown.

Congenital 52

Congenital Aortic Stenosis Aortic valve 52

Frontiers in Cardiovascular Medicine

AUGUST 7, 2024

Aortic Stenosis (AS) is a common condition with an estimated pooled prevalence of all AS in the elderly population at around 12.4%, with that of severe AS estimated to be around 3.4%. In the past, surgical aortic valve replacement was the primary treatment option for severe AS for decades.

Aortic valve 98

Aortic valve Aortic TAVR Peripheral Arterial Disease 98

Heart BMJ

FEBRUARY 26, 2025

A significant proportion of patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) have concomitant coronary artery disease (CAD). The best way to treat these patients is contentious.

Coronary Artery Disease 59

Coronary Artery Disease Stenosis Aortic Aortic valve 59

Society of Thoracic Surgeons - Adult Cardiac

JANUARY 26, 2025

Shettys team followed 252 patients who underwent the Ross procedure, a heart valve replacement operation commonly used to treat younger patients with severe aortic valve disease. Freedom from aortic regurgitation was 95.1%, 92.2%, 87.7%, and 84.5% Shettys team found that survival rates were 95.8% at 5 years, 94.3%

Aortic valve 83

Aortic valve Cardiothoracic Aortic Congenital 83

JAMA Cardiology

MAY 14, 2024

This cohort study examines whether there is an association between osteosarcopenia and adverse outcomes, such as increased risk of mortality, in older adults following transcatheter aortic valve replacement (TAVR).

Aortic valve 83

Aortic valve Aortic TAVR Outcomes 83

DAIC

JANUARY 29, 2024

Getty Images milla1cf Mon, 01/29/2024 - 14:24 January 29, 2024 — Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis , many hospitals are still opting for a nonsurgical approach in patients under 60—possibly with poorer survival rates.

Aortic valve 111

Aortic valve TAVR Aortic Outcomes 111

American College of Cardiology

MAY 24, 2024

What is the relationship between aortic valve calcification (AVC) and aortic stenosis (AS) severity in patients with suspected low-flow low-gradient AS?

Aortic valve 72

Aortic valve Aortic Stenosis Article 72

Medical Xpress - Cardiology

SEPTEMBER 3, 2024

Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

Aortic valve 75

Aortic valve Aortic Stenosis Research 75

Frontiers in Cardiovascular Medicine

FEBRUARY 17, 2025

IntroductionSince TAVR was approved for lower-risk aortic stenosis (AS) patients, managing post-implantation conduction disturbances has become crucial, especially with self-expanding heart valves (SEV).

Pacemaker 52

Pacemaker Aortic Stenosis Aortic valve 52

Med Page Today

OCTOBER 28, 2024

(MedPage Today) -- Transcatheter aortic valve replacement (TAVR) yielded clinical benefit when given early in the disease process while patients still had no symptoms or other indication for aortic valve replacement, according to the EARLY TAVR.

TAVR 105

TAVR Aortic Aortic valve Stenosis 105

Open Heart

JANUARY 8, 2024

Background A quarter of patients with severe aortic stenosis (AS) were asymptomatic, and only a third of them survived at the end of 4 years. Only a select subset of these patients was recommended for aortic valve replacement (AVR) by the current American College of Cardiology/American Heart Association guidelines.

Aortic valve 98

Aortic valve Aortic Preserved Ejection Fraction Stenosis 98

Frontiers in Cardiovascular Medicine

JANUARY 30, 2025

Bileaflet mechanical heart valves (MHV) remain a viable option for aortic valve replacement, particularly for younger patients and patients from low- and middle-income countries and underserved communities. Despite their exceptional durability, MHV recipients are at increased risk of thromboembolic complications.

Heart Valves 52

Heart Valves Aortic Aortic valve Blood Clot 52

Open Heart

JANUARY 19, 2025

Background Cardiogenic shock (CS) induced by severe aortic stenosis (AS) is a life-threatening condition with high mortality. Aim This study aimed to systematically review and analyse the existing evidence on outcomes of emergency transcatheter aortic valve implantation (eTAVI) and emergency balloon aortic valvuloplasty (eBAV) in CS patients.

Cardiogenic Shock 52

Cardiogenic Shock Aortic Stenosis Aortic valve 52

Open Heart

FEBRUARY 27, 2024

Objectives The clinical outcomes of transcatheter aortic valve replacement (TAVR) in patients with aortic stenosis (AS) and concomitant active cancer remain insufficiently explored. This study aimed to assess the midterm outcomes of TAVR in patients diagnosed with AS and active cancer.

Aortic valve 98

Aortic valve Cancer Aortic TAVR 98

Journal of Cardiothoracic Surgery

MARCH 25, 2025

Quadricuspid aortic valve (QAV) is rare. However, to repair a quadricuspid aortic valve is not as easy to realize as in bicuspid aortic valve. The surgical design is crucial to rebuild the stable structure.

Aortic valve 52

Aortic valve Aortic Tricuspid Bicuspid/Mitral 52

Heart BMJ

FEBRUARY 26, 2025

In the 22 years since Professor Alain Cribier performed the first transcatheter aortic valve implantation (TAVI) in Rouen in France, treatment pathways for patients with aortic valve stenosis have evolved rapidly.

Aortic valve 59

Aortic valve Aortic Stenosis 59

JAMA Cardiology

JULY 16, 2024

This meta-analysis evaluates lipoprotein(a) concentrations and hemodynamic progression in patients with aortic stenosis.

Stenosis 93

Stenosis Aortic valve Aortic 93

American College of Cardiology

SEPTEMBER 18, 2024

The goal of the AVATAR trial was to evaluate aortic valve replacement (AVR) compared with conservative therapy among patients with asymptomatic severe aortic stenosis.

Aortic valve 64

Aortic valve Aortic Stenosis Article 64

Science Daily - Heart Disease

JANUARY 15, 2025

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease.

Aortic valve 74

Aortic valve Bicuspid/Mitral Aortic 74

DAIC

APRIL 25, 2024

Aortic stenosis is a narrowing of the aortic valve which prevents the aortic leaflets from opening and closing properly. Patients with aortic stenosis often have heart murmurs and experience debilitating symptoms including chest pain, dizziness, fatigue, shortness of breath and an irregular heartbeat.

Heart Valves 105

Heart Valves Stenosis Aortic Aortic valve 105

Journal of Cardiothoracic Surgery

MARCH 7, 2025

Quadricuspid aortic valve (QAV) is a rare congenital anomaly of the aortic valve, with an incidence of 0.05-0.1%, 0.1%, often associated with aortic regurgitation. The condition typically presents between the ages o.

Aortic valve 52

Aortic valve Aortic Congenital 52

Frontiers in Cardiovascular Medicine

JANUARY 15, 2024

Objectives To evaluate the results of the inoperable and operable with aortic valve endocarditis, focus on risk factors, significance, and management of destruction of the aortic annulus in aortic valve endocarditis. There were 32 operative deaths (6.3%, 32/512).

Aortic valve 64

Aortic valve Aortic Best Practices Risk Factors 64