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Rare genetic variants linked to bicuspid aortic valve disease in young adults identified

Medical Xpress - Cardiology

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

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Dedicated trial in women demonstrates the superiority of transcatheter vs. surgical aortic valve replacement

Medical Xpress - Cardiology

Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

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Researchers ID Genetic Variants Linked to Bicuspid Aortic Valve Disease

DAIC

1, 2024 — Researchers at UTHealth Houston have identified genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications. tim.hodson Wed, 09/04/2024 - 15:53 Sept.

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Third Nordic Aortic Valve Intervention

American College of Cardiology

The goal of the NOTION-3 trial was to evaluate percutaneous coronary intervention (PCI) compared with conservative therapy among patients with obstructive coronary artery disease undergoing transcatheter aortic valve implantation (TAVI).

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Alternative access in transcatheter aortic valve replacement—an updated focused review

Frontiers in Cardiovascular Medicine

Aortic Stenosis (AS) is a common condition with an estimated pooled prevalence of all AS in the elderly population at around 12.4%, with that of severe AS estimated to be around 3.4%. In the past, surgical aortic valve replacement was the primary treatment option for severe AS for decades.

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Routine Protamine Administration for Bleeding in Transcatheter Aortic Valve Implantation

JAMA Cardiology

This randomized clinical trial evaluates the safety and efficacy of administration of protamine to reduce bleeding following transcatheter aortic valve implantation vs placebo, selective protamine administration.

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Sarcopenia and aortic valve disease

Heart BMJ

Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).