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Aortic valve Strokes TAVR 
DAIC
JANUARY 29, 2024
Getty Images milla1cf Mon, 01/29/2024 - 14:24 January 29, 2024 — Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis , many hospitals are still opting for a nonsurgical approach in patients under 60—possibly with poorer survival rates.
111 
Med Page Today
JUNE 5, 2024
(MedPage Today) -- NEW YORK CITY -- Researchers eked out evidence of a small clinical benefit with the Sentinel cerebral embolic protection (CEP) device in transcatheter aortic valve replacement (TAVR) -- and pointed to the patients more likely.
100 
DAIC
MARCH 31, 2025
Data shows, versus surgery, the Evolut transcatheter aortic valve replacement (TAVR) system delivers a numerically lower rate of all-cause mortality or disabling stroke at five years, strong valve performance and durable clinical outcomes. Evolut TAVR vs. 9.3% Evolut TAVR vs. 9.3% Grubb, M.D.,
52 
DAIC
MARCH 25, 2024
Molham Aldeiri , have successfully performed the first series of transcarotid Transcatheter Aortic Valve Replacement (TAVR) procedures ever done in Southeast Houston. TAVR , whether through the groin approach or neck approach, only requires a half-inch or inch incision.
111 
DAIC
APRIL 30, 2024
SAVR after TAVR Surgical aortic valve replacement after prior TAVR is the fastest-growing cardiac surgery procedure in the U.S. The majority require explant of the TAVR device and SAVR, which significantly increases the risk of operative mortality and stroke. and 3.8%, respectively.
111 
Becker's Hospital Review - Cardiology
JANUARY 5, 2024
A recent study found patients who undergo transcatheter aortic valve replacement have higher risk of stroke for up to two years after the procedure.
69 
American College of Cardiology
AUGUST 14, 2024
What is the relationship between diffusion-weighted magnetic resonance imaging (DW-MRI) total lesion number (TLN), individual lesion volume (ILV), and total lesion volume (TLV) with clinical stroke outcomes after transcatheter aortic valve replacement (TAVR)?
53 
DAIC
JANUARY 29, 2024
Cardiac Surgery after Transcatheter Aortic Valve Replacement: Trends and Outcomes The researchers set out to document trends and outcomes in cardiac surgery following transcatheter aortic valve replacement (TAVR), a topic gaining importance as reports of subsequent cardiac operations and early TAVR explantations increase.
111 
Circulation
NOVEMBER 11, 2024
Seven studies showed that TAVR patients had a similar 1-year stroke risk to SAVR patients (OR 0.92, 95% CI 0.64 In the TIA case, there was no evidence of a significant difference between TAVR and SAVR in the risk of having a transient ischemic attack within 30 days following surgery (OR 0.93, 95% CI 0.24 to 1.17, p=0.30, I2 3%).
40 
American College of Cardiology
OCTOBER 29, 2024
The goal of the PROTECTED TAVR trial was to evaluate the efficacy of intraprocedural cerebral embolic protection (CEP) in reducing strokes among patients undergoing transfemoral TAVR for aortic stenosis.
45 
European Journal of Heart Failure
JANUARY 31, 2024
TAVR in heart failure. ABSTRACT Patients with severe aortic stenosis (AS) may develop heart failure (HF), the presence of which has traditionally been deemed as a final stage in AS progression with poor outcomes. The prognostic covariates and optimal timing of TAVR in patients with less than severe AS remain unclear.
40 
The British Journal of Cardiology
FEBRUARY 20, 2024
Patients with bicuspid aortic valves (BAV) are predisposed to the development of aortic stenosis. We performed a pairwise meta-analysis, comparing the efficacy of transcatheter aortic valve replacement (TAVR) versus surgical aortic valve replacement (SAVR) in patients with BAV.
40 
Journal of the American Heart Association
FEBRUARY 13, 2024
BackgroundAcute ischemic stroke complicates 2% to 3% of transcatheter aortic valve replacements (TAVRs). The aortic arch morphology was determined via a manual review of the pre‐TAVR computed tomography images. Fifty‐seven patients (1.7%) experienced a periprocedural stroke. versus 1.7%;P=0.01).
40 
Journal of the American Heart Association
FEBRUARY 14, 2025
BackgroundValveinvalve transcatheter aortic valve replacement (TAVR) is a recognized alternative for treating the structural valve deterioration of bioprosthetic valves. Recent guidelines and trials have expanded the indications for TAVR to include younger patients with structural valve deterioration.
40 
Open Heart
JANUARY 19, 2023
Objective Postprocedural ischaemic and bleeding risks after transcatheter aortic valve replacement (TAVR) remain a major concern. We aimed to assess the accuracy of percutaneous coronary intervention (PCI)-derived models and the performance of a recalibrated model that included variables more applicable to TAVR.
52 
DAIC
MARCH 12, 2024
A cost-effectiveness analysis demonstrates the positive economic value of transcatheter aortic valve replacement (TAVR) using Evolut TAVR compared to surgical aortic valve replacement (SAVR) for low-risk patients. At Medtronic, we continue to emphasize that valve design matters.
52 
Circulation
NOVEMBER 11, 2024
Introduction:Subclinical leaflet thrombosis is an increasingly recognized complication in patients undergoing transcatheter aortic valve replacement (TAVR). Patients with hypoattenuated leaflet thickening (HALT) and reduced leaflet motion (RELM) have a higher incidence of strokes and transient ischemic attacks.
40 
Circulation
OCTOBER 23, 2023
Background: Atrial fibrillation (AF) is common in patients undergoing transcatheter aortic valve replacement (TAVR) and is associated with increased risk of bleeding and stroke. Patients were randomized 1:1 to TAVR+LAAO or TAVR+medical therapy. For the composite primary endpoint, TAVR+.LAAO
40 
Circulation
OCTOBER 25, 2023
The objectives of this study were to compare the hemodynamic and clinical outcomes between transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in patients with a SAA.Methods:Prospective multicenter international randomized trial performed in 15 university hospitals.
40 Coronary Artery Disease Journal
MAY 13, 2024
Objective To investigate the impact of prior coronary artery bypass grafting (CABG) and coronary lesion complexity on transcatheter aortic valve replacement (TAVR) outcomes for aortic stenosis. The CABG SYNTAX score did not influence the prognosis after TAVR.
Circulation: Cardiovascular Interventions
OCTOBER 22, 2023
Background:Atherosclerotic cardiovascular disease (ASCVD) is highly prevalent in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR). Exposure of interest was PVD. Primary outcome was all-cause mortality. 2VB-PVD, HR 1.12; 95% CI, 1.09-1.15, 1.15, and 3VB-PVD, HR 1.31; 95% CI, 1.26-1.36).
40 
DAIC
FEBRUARY 29, 2024
24 will focus on the following three current guideline updates: American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines 2023 Atrial Fibrillation Guideline - Pharmacology II: Strokes vs. Bleeds, What Do the Guidelines Tell Us About Practical Management in A-fib? The Guidelines Sessions at ACC.24
103 
DAIC
JUNE 7, 2024
milla1cf Fri, 06/07/2024 - 14:50 June 7, 2024 — Medtronic today announced new data from the CoreValve Evolut Clinical Program , reinforcing the positive performance of the Evolut transcatheter aortic valve replacement (TAVR) System compared to surgical aortic valve replacement (SAVR) and other TAVR valves.
111 
Dr. S. Venkatesan MD
JANUARY 17, 2025
We know TAVI is in the striking distance , to literally take over most aortic valve interventions. While the numbers increase, still the debate between SAVR and TAVR is riddled with speculation, skepticism, and absolute confidence. Lastly, TAVI’s lifespan* is currently less than half of a mechanical valve.
52 
Cardiology Update
FEBRUARY 6, 2024
Stroke stands as a major contributor to global morbidity and mortality, imposing a substantial burden on patients, societies, and healthcare systems worldwide. Within the realm of transcatheter aortic valve replacement (TAVR), stroke emerges as a recognized adverse event, manifesting at various stages during and after the procedure.
111 
DAIC
APRIL 11, 2024
TAVR and SAVR are procedures to replace a damaged aortic valve that is not functioning properly. TAVR and SAVR are procedures to replace a damaged aortic valve that is not functioning properly. Researchers randomly assigned half of the participants to undergo TAVR and the other half to SAVR.
111 
DAIC
MAY 15, 2024
Getty Images milla1cf Wed, 05/15/2024 - 19:10 May 15, 2024 — A new study demonstrated parity between a minimally invasive procedure to replace the aortic valve in the heart— transcatheter aortic valve replacement (TAVR)—and surgical aortic valve replacement (SAVR).
105 
DAIC
MAY 1, 2024
According to the Centers for Disease Control and Prevention (CDC), heart disease and stroke rank as the first and fifth leading causes of death in the nation. About 276,000 patients have undergone a TAVR procedure in the United States.
DAIC
APRIL 9, 2024
The SMART trial is the first randomized head-to-head comparison of the two most widely used TAVR devices—the supra-annular self-expanding Evolut PRO/PRO+/FX and the balloon-expandable SAPIEN 3/3 Ultra. percentage points—in one-year bioprosthetic valve dysfunction favoring the Evolut platform. of those receiving the SAPIEN valve.
59 The New England Journal of Medicine
JANUARY 15, 2025
Among patients with asymptomatic severe aortic stenosis, early TAVR was superior to clinical surveillance in reducing the incidence of death, stroke, or unplanned hospitalization for cardiovascular causes.
74 
Open Heart
MAY 12, 2023
Objective To evaluate whether transcatheter or surgical aortic valve replacement (TAVR or SAVR) affects clinical and haemodynamic outcomes in symptomatic patients with moderately-severe aortic stenosis (AS). <aortic valve area (AVA)<1.5 <aortic valve area (AVA)<1.5 cm 2 , 3.0<peak
52 Stroke Journal
JANUARY 30, 2025
Stroke, Volume 56, Issue Suppl_1 , Page ATP316-ATP316, February 1, 2025. Background:Despite improvements in the safety of transcatheter aortic valve replacement (TAVR), ~4% of patients experience a procedure-related stroke. Further research is needed to assess confounding factors as well.
40 
Cardiology Update
NOVEMBER 26, 2023
In light of the growing number of patients undergoing transcatheter aortic valve replacement (TAVR), there is an increasing demand for data regarding the management of failed TAVR procedures, including the possibility of a repeat TAVR intervention. vs. 19.0%, p=0.57), as well as stroke at 30 days (2.0%
52 
Circulation: Cardiovascular Interventions
MARCH 26, 2025
BACKGROUND:Current guidelines recommend surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis and unfavorable iliofemoral access. At 30 days, the SAVR group showed a higher rate of the primary composite outcome compared with the TC-TAVR group (12.6% andP=0.001, respectively).
40 
American College of Cardiology
APRIL 8, 2024
TAVR was found to bring no increased risks and was associated with substantially decreased rates of death or stroke at one year in low-risk patients, compared with surgical aortic valve replacement (SAVR), according to results from the DEDICATE-DZHK6 study presented during a Late-Breaking Clinical Trial session at ACC.24
56 American College of Cardiology
OCTOBER 29, 2024
In women with symptomatic, severe aortic stenosis (AS), TAVR with the balloon-expandable valve was superior to surgical aortic valve replacement in terms of the composite rate of death, stroke and rehospitalization at one-year follow-up, according to a pooled analysis of patient-level data from RHEIA and PARTNER 3 trials presented at TCT 2024.
50 Journal of the American Heart Association
MARCH 21, 2025
BackgroundCurrent guidelines and expert consensus recommend lifelong single antiplatelet therapy for patients undergoing transcatheter aortic valve replacement who have no indication for anticoagulation or dual antiplatelet therapy. Journal of the American Heart Association, Ahead of Print.
40 
American College of Cardiology
FEBRUARY 18, 2025
The EARLY TAVR trial results demonstrate that early transcatheter aortic valve implantation in patients with asymptomatic severe aortic stenosis is superior to clinical surveillance in significantly reducing the composite primary outcome of death, stroke, or unplanned hospitalization for cardiovascular causes.
61 Journal of Cardiovascular Pharmacology
NOVEMBER 21, 2023
Abstract: Transcatheter aortic valve replacement (TAVR) is an interventional procedure performed in patients with severe aortic stenosis and often required perioperative antiplatelet therapy. Most previous studies have focused on antiplatelet therapy following TAVR.
40 
The New England Journal of Medicine
NOVEMBER 22, 2023
Among patients at low surgical risk who underwent TAVR or surgery, there was no apparent difference between groups in the incidence of the composite end point of death, stroke, or rehospitalization at 5 years.
40 
Society of Thoracic Surgeons - Congenital
OCTOBER 17, 2023
Database, Study in Low-Risk Patients Reveals 5-year Survival Rate of 93% October 17, 2023, Chicago, IL – A study published today in The Annals of Thoracic Surgery demonstrates outstanding long-term survival following low-risk isolated surgical aortic valve replacement (SAVR). The average age of patients was 74.2
40 
Cardiology Update
APRIL 9, 2024
SMART 4 ( NCT04722250 ) studied patients with severe aortic stenosis and a small aortic annulus who underwent transcatheter aortic valve replacement (TAVR). A total of 716 patients underwent TAVR with either a self-expanding supraannular valve or a balloon-expandable valve.
52 
Society of Thoracic Surgeons - Research
APRIL 20, 2023
Adult Cardiac Surgery Database Lead Author Title Publication Date Jacob Raphael Red Blood Cell Transfusion and Pulmonary Complications: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis The Annals of Thoracic Surgery January 2024 Joseph Sabik Multi-Arterial versus Single-Arterial Coronary Surgery: Ten Year Follow-up of One Million (..)
52 
Society of Thoracic Surgeons - Research
APRIL 20, 2023
Program Designations Access and Publications (A&P) 1 Participant User File (PUF) 2 Task Force on Funded Research (TFR) 3 Special Projects 4 Adult Cardiac Surgery Database Lead Author Title Publication Date William Keeling 2 National Trends in Emergency Coronary Artery Bypass Grafting European Journal of Cardiothoracic Surgery October 2023 Jake (..)
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