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Dedicated trial in women demonstrates the superiority of transcatheter vs. surgical aortic valve replacement

Medical Xpress - Cardiology

Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

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TAVI Matches SAVR in Lower Risk Aortic Valve Patients: 10 year outcomes

Cardiology Update

The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk.

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Abstract 4142104: Ischemic Stroke and TIA Incidence in Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement: A Comparative Systematic Review and Meta-analysis

Circulation

Seven studies showed that TAVR patients had a similar 1-year stroke risk to SAVR patients (OR 0.92, 95% CI 0.64 Odds ratios (ORs) with 95% confidence intervals (CIs) for each study, employing a random-effects model for data synthesis irrespective of heterogeneity, were utilized as measures of outcomes. to 1.17, p=0.30, I2 3%).

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Systematic review and meta-analysis of early aortic valve replacement versus conservative therapy in patients with asymptomatic aortic valve stenosis with preserved left ventricle systolic function

Open Heart

Background A quarter of patients with severe aortic stenosis (AS) were asymptomatic, and only a third of them survived at the end of 4 years. Only a select subset of these patients was recommended for aortic valve replacement (AVR) by the current American College of Cardiology/American Heart Association guidelines.

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The neo-aortic valve in patients with hypoplastic left heart syndrome is largely preserved: a serial follow-up CMR study

Frontiers in Cardiovascular Medicine

BackgroundIn hypoplastic left heart syndrome (HLHS) patients, neo-aortic valve regurgitation can negatively impact right ventricular (RV) function. RV end-diastolic and end-systolic volumes normalised to body surface area (BSA, RVEDVi, RVESVi), ejection fraction (RVEF) and stroke volume (RVSV) were measured.

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Right anterior thoracotomy vs. upper hemisternotomy for aortic valve replacement with Perceval S: is there a difference?

Frontiers in Cardiovascular Medicine

There were no statistically significant differences in terms of stroke, paravalvular leak, mechanical ventilation time, blood transfusion requirements, pacemaker implantation, reexploration for bleeding, conversion, wound infection, or in-hospital stay. This was a retrospective, single-center observational study.

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Stroke PROTECTion With SEntinel During Transcatheter Aortic Valve Replacement

American College of Cardiology

The goal of the PROTECTED TAVR trial was to evaluate the efficacy of intraprocedural cerebral embolic protection (CEP) in reducing strokes among patients undergoing transfemoral TAVR for aortic stenosis.