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New Study Suggests that Amyloid Contributes to Calcific Aortic Valve Disease Development

DAIC

Getty Images milla1cf Fri, 06/07/2024 - 15:10 June 7, 2024 — Calcific aortic valve disease (CAVD) is the major heart valve disease that afflicts nearly 10 million patients globally with an annual mortality exceeding 100,000, and the numbers continue to rise.

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Functional assessment of coronary artery disease in patients with severe aortic stenosis: a review

Heart BMJ

A significant proportion of patients with severe aortic stenosis (AS) undergoing transcatheter aortic valve implantation (TAVI) have concomitant coronary artery disease (CAD). A better understanding of how we assess and interpret coronary physiology in these patients is required to optimise treatment pathways.

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A NOTIONal truth : Surgical AVR deteriorates faster than TAVI, for some mysterious reasons!

Dr. S. Venkatesan MD

Is it Ok to define structural valve dysfunction(SVD) based on gradient alone ? Flow is physiology. Sub physiological valve destruction very much possible without affecting gradient. Is there any meaningful explanation why surgeons valve deteriorated fast ? It was not mandatory. Did TEE/CT follow up imaging done ?

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Magenta Medical, Developer of World’s Smallest Heart Pump, Closes $105M Financing Round

DAIC

The pump is delivered into the heart fully sheathed, over a guidewire, through the aorta, and across the aortic valve. It further notes the following on the technology: The Elevate pump is first folded and then inserted percutaneously through a small puncture in the groin to accommodate a commercially available 10 Fr introducer sheath.

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Learning some crucial cardiovascular hemodynamic lessons* from Giraffe 

Dr. S. Venkatesan MD

An Aortic Impella device, that is distal to the aortic valve and devoid of LV-related issues. The hemodynamic of the Giraffe’s vascular system is a good physiologic model of circulation, that defy gravity. Shall we think about,axial pumps in ascending Aorta in series with LV.

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A young woman with palpitations. What med is she on? With what medication is she non-compliant? What management?

Dr. Smith's ECG Blog

As per Dr. Meyers — Given the context of a patient with known AFlutter since her aortic valve repair — for which she had been taking the Flecainide but not the Metoprolol she was prescribed — ECG #2 almost certainly represented conversion of her AFlutter from 2:1 to 1:1 AV conduction. Did You Calculate Atrial and Ventricular Rates?

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Diffuse Subendocardial Ischemia on the ECG. Left main? 3-vessel disease? No!

Dr. Smith's ECG Blog

The diagnostic coronary angiogram identified only minimal coronary artery disease, but there was a severely calcified, ‘immobile’ aortic valve. Aortic angiogram did not reveal aortic dissection. If you see this, you should Doppler the valve. Aortic valve surgery as an emergency procedure. Circulation.