article thumbnail

Sarcopenia and aortic valve disease

Heart BMJ

Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).

article thumbnail

Almost 50% of Patients Under 60 Years Choose TAVR Over Surgical Aortic Valve Replacement with Worse Outcomes

DAIC

Getty Images milla1cf Mon, 01/29/2024 - 14:24 January 29, 2024 — Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis , many hospitals are still opting for a nonsurgical approach in patients under 60—possibly with poorer survival rates.

article thumbnail

Link between gene duplications and deletions within chromosome region and nonsyndromic bicuspid aortic valve disease

Science Daily - Heart Disease

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease.

article thumbnail

Increased testing for heart disease indicator needed worldwide, say experts

Medical Xpress - Cardiology

A review in The Lancet finds that 20% of the world population carries a genetic risk factor for cardiovascular diseases such as heart attacks, strokes, and aortic valve stenosis: Increased levels of a lipid particle called lipoprotein(a). It is the most common genetic cause of cardiovascular diseases.

article thumbnail

New study suggests that amyloid contributes to calcific aortic valve disease development

Science Daily - Heart Disease

Researchers have now proposed a molecular mechanism that links amyloid deposition in the aortic valve with degenerative calcification.

article thumbnail

Can this device prevent a stroke during a heart valve operation? New research shows potential benefit

Science Daily - Heart Disease

Recently published research shows a medical device may be beneficial for patients who have previously had a stroke and are planning to undergo a transcatheter aortic valve replacement, a type of heart valve operation.

article thumbnail

Early and mid-term outcomes of transcatheter closure of perimembranous ventricular septal defects using double-disc occluders

Frontiers in Cardiovascular Medicine

IntroductionVentricular septal defect (VSD) is a common congenital heart disease (CHD), accounting for 2030% of all CHD cases. ResultsThe procedure achieved a success rate of 96.4%, with three failures due to large defects near the aortic valve causing significant aortic regurgitation or residual shunting.

VSD 52