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New Study Suggests that Amyloid Contributes to Calcific Aortic Valve Disease Development

DAIC

Getty Images milla1cf Fri, 06/07/2024 - 15:10 June 7, 2024 — Calcific aortic valve disease (CAVD) is the major heart valve disease that afflicts nearly 10 million patients globally with an annual mortality exceeding 100,000, and the numbers continue to rise.

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Sarcopenia and aortic valve disease

Heart BMJ

Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).

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Almost 50% of Patients Under 60 Years Choose TAVR Over Surgical Aortic Valve Replacement with Worse Outcomes

DAIC

Getty Images milla1cf Mon, 01/29/2024 - 14:24 January 29, 2024 — Despite national guidelines recommending surgical aortic valve replacement (SAVR) for patients under age 65 with severe aortic stenosis , many hospitals are still opting for a nonsurgical approach in patients under 60—possibly with poorer survival rates.

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Link between gene duplications and deletions within chromosome region and nonsyndromic bicuspid aortic valve disease

Science Daily - Heart Disease

Large and rare duplications and deletions in a chromosome region known as 22q11.2 , which involves genes that regulate cardiac development, are linked to nonsyndromic bicuspid aortic valve disease.

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Increased testing for heart disease indicator needed worldwide, say experts

Medical Xpress - Cardiology

A review in The Lancet finds that 20% of the world population carries a genetic risk factor for cardiovascular diseases such as heart attacks, strokes, and aortic valve stenosis: Increased levels of a lipid particle called lipoprotein(a). It is the most common genetic cause of cardiovascular diseases.

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Reinterventions in patients with congenital aortic stenosis and a commissurotomy

Open Heart

However, there is often a need for future additional interventions on the aortic valve. The fate of the aortic valve is, however, essentially unknown. This study reports the need for reinterventions after surgical commissurotomy, based on a national register.

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Ismail El-Hamamsy, MD, PhD, Named President of the Heart Valve Society

DAIC

He previously served on the HVS Board of Directors and has led the HVS AVIATOR Registry, an international registry examining outcomes after aortic valve surgery. I am very excited and honored to lead the Heart Valve Society and further consolidate its role as a unique society dedicated to valvular heart disease. “I