Circulation

MARCH 29, 2025

Circulation, Ahead of Print. Background: Symptomatic severe aortic stenosis (AS) remains undertreated with high resultant mortality despite increased growth and availability of aortic valve replacement (AVR) since the advent of transcatheter therapies. cm2were enrolled. cm2were enrolled. with EPN versus 37.2%

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Aortic Stenosis Aortic valve Academic 45

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4119619-A4119619, November 12, 2024. Background:Peak aortic valve Doppler velocity, mean aortic valve gradient, and Doppler estimated aortic valve area are key measures recommended for assessing aortic stenosis severity.

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Stenosis Aortic valve Aortic Echocardiogram 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142104-A4142104, November 12, 2024.

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Aortic valve Aortic TAVR Stroke 40

Circulation: Cardiovascular Interventions

APRIL 7, 2025

Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:The extent of cardiac damage has been shown to be associated with increased mortality, repeat hospitalization, and decreased quality of life after aortic valve replacement (AVR).

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Aortic valve Aortic Heart Failure Quality of Life 40

Circulation

OCTOBER 25, 2023

Circulation, Ahead of Print. Background:The optimal treatment in patients with severe aortic stenosis (AS) and small aortic annulus (SAA) remains to be determined.

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Aortic valve Aortic TAVR Stenosis 40

Circulation: Cardiovascular Imaging

JANUARY 8, 2025

Circulation: Cardiovascular Imaging, Ahead of Print.

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Aortic valve Aortic Stenosis Cardiovascular Imaging 40

Circulation

JUNE 17, 2024

Circulation, Ahead of Print. Severe disease is managed with valve replacement procedures, which entail high health care–related costs and postprocedural morbidity and mortality. Valvular heart disease is a common cause of morbidity and mortality worldwide and has no effective medical therapy.

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Bicuspid/Mitral Heart Disease Aortic valve Heart Valves 65

Open Heart

MARCH 24, 2023

Our perspectives on aortic stenosis (AS) are changing. Novel approaches are developing to address this through: (1) screening with circulating biomarkers; (2) development of drugs to slow disease progression and (3) early valve intervention guided by medical imaging.

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Stenosis Aortic Aortic valve Biomarkers 52

DAIC

FEBRUARY 3, 2025

Lp(a) is emerging as an important, yet under-recognized, potential risk factor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. Circulation. 2022 Aug, 80 (9) 934946 Kronenberg F. Arnett DK et al. 2019 Sep 10;140(11):e563-e595.

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Cardiovascular Disease Aortic valve Biomarkers Innovation 52

Circulation: Cardiovascular Interventions

OCTOBER 22, 2023

Circulation: Cardiovascular Interventions, Ahead of Print. Background:Atherosclerotic cardiovascular disease (ASCVD) is highly prevalent in patients with severe aortic stenosis undergoing transcatheter aortic valve replacement (TAVR).

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Aortic valve Aortic TAVR Outcomes 40

Circulation: Cardiovascular Interventions

NOVEMBER 9, 2023

Circulation: Cardiovascular Interventions, Ahead of Print.

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Aortic valve Aortic Cardiovascular Interventions Stenosis 40

Circulation

OCTOBER 23, 2023

Circulation, Ahead of Print. Background: Atrial fibrillation (AF) is common in patients undergoing transcatheter aortic valve replacement (TAVR) and is associated with increased risk of bleeding and stroke. For the composite primary endpoint, TAVR+.LAAO LAAO was non-inferior to TAVR+ medical therapy (22.7

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Aortic valve Atrial Fibrillation TAVR Aortic 40

The British Journal of Cardiology

AUGUST 1, 2024

Lipoprotein(a) (Lp[a]) can improve the accuracy of assessment of atherosclerotic cardiovascular disease and the risk of aortic valve stenosis. Currently, there is no specific treatment to lower its circulating concentration. Raised Lp(a) is a feature of familial hypercholesterolaemia.

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Aortic valve Heart Disease Blood Pressure Stenosis 40

Circulation: Cardiovascular Quality & Outcomes

DECEMBER 13, 2023

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. The primary outcome was a composite of all-cause mortality or hospital readmission within 1 year.

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TAVR Aortic valve Aortic Outcomes 40

Circulation: Cardiovascular Imaging

OCTOBER 25, 2023

Circulation: Cardiovascular Imaging, Volume 16, Issue 11 , Page e016039, November 1, 2023.

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Aortic valve Cardiovascular Imaging Article Aortic 40

Circulation: Cardiovascular Imaging

OCTOBER 25, 2023

Circulation: Cardiovascular Imaging, Volume 16, Issue 11 , Page e016088, November 1, 2023.

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Aortic valve Cardiovascular Imaging Article Aortic 40

Dr. Smith's ECG Blog

NOVEMBER 19, 2016

The diagnostic coronary angiogram identified only minimal coronary artery disease, but there was a severely calcified, ‘immobile’ aortic valve. Aortic angiogram did not reveal aortic dissection. If you see this, you should Doppler the valve. In fact, bedside ultrasound might even find severe aortic stenosis.

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Ischemia Cardiogenic Shock Aortic Stenosis 40

DAIC

MARCH 28, 2024

milla1cf Thu, 03/28/2024 - 07:30 March 28, 2024 — Medtronic plc, a global leader in healthcare technology, announced that the United States Food and Drug Administration ( FDA ) has approved the Evolut FX+ transcatheter aortic valve replacement (TAVR) system for the treatment of symptomatic severe aortic stenosis.

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TAVR Stenosis Aortic Aortic valve 111

Circulation: Cardiovascular Interventions

MARCH 26, 2025

Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Current guidelines recommend surgical aortic valve replacement (SAVR) for patients with severe aortic stenosis and unfavorable iliofemoral access.

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Aortic valve Aortic Stenosis TAVR 40

Journal of the American Heart Association

FEBRUARY 26, 2025

BackgroundCardiac fibrosis is common in patients with severe aortic stenosis and an independent predictor of death. Combined with highsensitivity cardiac troponin T, circulating TIMP1 should be incorporated into risk stratification to identify patients undergoing TAVR who are at a higher risk of death. 95% CI, 2.69.7];P<0.001)

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Aortic valve Aortic TAVR Biomarkers 45

Circulation: Cardiovascular Interventions

JANUARY 18, 2024

Circulation: Cardiovascular Interventions, Ahead of Print. Background:Frailty associates with worse outcomes after transcatheter aortic valve replacement (TAVR). Cross-sectional muscle (psoas and paraspinal) areas were measured on computed tomography and indexed to height. per 1 SD decrease [95% CI, 1.15–1.89];P=0.002)

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Aortic valve Aortic TAVR Stenosis 40

Heart BMJ

MARCH 22, 2024

Objectives This study aimed to evaluate the prognostic value of coronary microvascular dysfunction (CMD) at long term after transcatheter aortic valve implantation (TAVI) and to explore its relationship with extravalvular cardiac damage (EVCD). CMD was defined as IMR angio ≥30 units.

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Aortic valve Aortic Tricuspid Heart Failure 40

Circulation

NOVEMBER 8, 2023

Circulation, Ahead of Print. BACKGROUND:High circulating levels of Lp(a) (lipoprotein[a]) increase the risk of atherosclerosis and calcific aortic valve disease, affecting millions of patients worldwide.

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Aortic valve Heart Disease Atherosclerosis Aortic 40

Cardiology Update

APRIL 9, 2024

SMART 4 ( NCT04722250 ) studied patients with severe aortic stenosis and a small aortic annulus who underwent transcatheter aortic valve replacement (TAVR). A total of 716 patients underwent TAVR with either a self-expanding supraannular valve or a balloon-expandable valve. It is able to deliver 3.5L/min

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Angina Myocardial Infarction Aortic valve Coronary Artery Disease 52

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Adult Cardiac Surgery Database Lead Author Title Publication Date Jacob Raphael Red Blood Cell Transfusion and Pulmonary Complications: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis The Annals of Thoracic Surgery January 2024 Joseph Sabik Multi-Arterial versus Single-Arterial Coronary Surgery: Ten Year Follow-up of One Million (..)

Research 52

Research Coronary Artery Bypass Graft Aortic valve Congenital 52

Society of Thoracic Surgeons - Research

APRIL 20, 2023

Program Designations Access and Publications (A&P) 1 Participant User File (PUF) 2 Task Force on Funded Research (TFR) 3 Special Projects 4 Adult Cardiac Surgery Database Lead Author Title Publication Date William Keeling 2 National Trends in Emergency Coronary Artery Bypass Grafting European Journal of Cardiothoracic Surgery October 2023 Jake (..)

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Research Coronary Artery Bypass Graft Aortic valve Congenital 52

Circulation

FEBRUARY 27, 2024

Circulation, Ahead of Print. A peak systolic pulmonary artery pressure >60 mm Hg during exercise has been associated with an increased risk of cardiovascular death, heart failure rehospitalization, and aortic valve replacement in aortic valve stenosis. P=0.001), E/e’ at rest (OR per SD, 1.61;P=0.012),

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Aortic valve Stenosis Aortic Atrial Fibrillation 75

Circulation: Cardiovascular Imaging

JANUARY 8, 2025

Circulation: Cardiovascular Imaging, Ahead of Print. BACKGROUND:Aortic valve calcification (AVC) has been shown to be a powerful assessment of aortic stenosis (AS) severity and a predictor of adverse outcomes. However, its accuracy in patients with low-flow AS has not yet been proven.

Aortic valve 40

Aortic valve Aortic Stenosis Cardiovascular Imaging 40

Med Page Today

FEBRUARY 25, 2025

(MedPage Today) -- The nitric oxide-independent soluble guanylate cyclase activator ataciguat continued to show promise for slowing the progression of fibrocalcific aortic valve stenosis in phase I and II studies. Circulation) The extent of myocardial.

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Stenosis Aortic Aortic valve Pacemaker 68

Dr. Smith's ECG Blog

MARCH 3, 2025

More troponin values were measured at the cardiac center: 2327- 267 ng/L 0821- 355 ng/L 1108- 305 ng/L An echocardiogram on day three of the patients admission showed an ejection fraction of 46% with abnormal basal inferior and basal lateral segments, and severe aortic stenosis. What "initiates" the aortic stenosis cascade?

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Tachycardia Pulmonary Chest Pain Stenosis 73