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Case Report: Rare cardiovascular characteristics of tuberous sclerosis complex with novel TSC2 variant

Frontiers in Cardiovascular Medicine

The co-occurrence of a bicuspid aortic valve (BAV) with TSC is exceedingly rare.Case summaryWe report the case of a 26-year-old woman with genetically confirmed TSC, harboring a novel pathogenic variant in the TSC2 gene. multi-system characteristics of TSC were also presented, affecting skin, brain, lung, kidney, and bone.

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'Tootsie Roll' Introduced for Leaky Transcatheter Heart Valves

Med Page Today

(MedPage Today) -- Operators reported the initial success of a novel transcatheter technique for treating complex paravalvular leaks (PVLs) after transcatheter aortic valve replacement (TAVR) or transcatheter mitral valve replacement (TMVR) in.

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Outcomes Following Transcatheter Aortic Valve Replacement for Aortic Stenosis in Patients With Type 0 Bicuspid, Type 1 Bicuspid, and Tricuspid Aortic Valves

Circulation: Cardiovascular Interventions

BACKGROUND:Data concerning the outcomes of transcatheter aortic valve replacement in type 0 bicuspid aortic stenosis (AS) are scarce. Self-expanding transcatheter heart valves were used in the majority of patients (n=1160; 91.4%). In the matched population, differences in mortality (30 days: 4.2%

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Unraveling the Mechanisms of Valvular Heart Disease to Identify Medical Therapy Targets: A Scientific Statement From the American Heart Association

Circulation

In this scientific statement, we review the basic cellular structures of the human heart valves and discuss how these structures change in primary valvular heart disease.

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Heart Valve Disease Forum 2024

Society of Thoracic Surgeons - Congenital

The conference theme is “Goldilocks: Toward the Optimal Mitral Valve,” and the organizers aim to bring together distinguished experts from around the world to share their knowledge and engage in academic discussions on the latest trends in treatments related to aortic valve disease. Details coming soon!

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Occurrence and predictors of pericardial effusion requiring invasive treatment following heart valve surgery

Open Heart

Objectives To describe the occurrence of significant pericardial effusion, and to investigate characteristics associated with pericardial effusion within three months following heart valve surgery. Data were gathered from The Western Denmark Heart Registry and electronic patient records. Being a man (HR 2.30, 95% CI 1.32

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Antithrombotic therapy after heart valve intervention: review of mechanisms, evidence and current guidance

Heart BMJ

As the population ages and treatment options for heart valve disease increase, the number of patients with intracardiac valve prostheses is growing rapidly. Mechanical valve prostheses carry the highest (and persistent) risk of thromboembolism, and these patients require anticoagulation with vitamin K antagonists (warfarin).