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Rare genetic variants linked to bicuspid aortic valve disease in young adults identified

Medical Xpress - Cardiology

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

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Researchers ID Genetic Variants Linked to Bicuspid Aortic Valve Disease

DAIC

1, 2024 — Researchers at UTHealth Houston have identified genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications. tim.hodson Wed, 09/04/2024 - 15:53 Sept.

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Later aorta operation after aortic valve replacement for bicuspid aortic valve

Journal of Cardiothoracic Surgery

We investigated long-term outcomes, particularly later aorta operations and overall death in patients who underwent aortic valve replacement for bicuspid aortic valve without aortic surgery.

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Bicuspid Aortic Valve Atorvastatin Treatment Study

American College of Cardiology

The goal of the BICATOR trial was to determine whether treatment with low to moderate dose atorvastatin is associated with progression of ascending aortic dilation, valvular dysfunction, or valve calcification in patients with bicuspid aortic valve.

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Case Report: Allograft aortic valve replacement in irreparable infant mitral valve

Frontiers in Cardiovascular Medicine

This case report describes a 3-month-old male infant diagnosed with severe mitral stenosis (MS) and mitral regurgitation (MR) by transthoracic echocardiography. The male infant initially underwent complex mitral valve repair surgery.

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Bicuspid aortic valve repair—current techniques, outcomes, challenges, and future perspectives

Frontiers in Cardiovascular Medicine

Bicuspid aortic valve (BAV) is a common congenital heart condition that can lead to some valve-related complications, such as aortic stenosis and/or regurgitation, and is often associated with aortic root dilation.

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Natural History of Bicuspid and Aneurysm-Associated Aortic Valve Disease

American College of Cardiology

Douglas Weaver MD, MACC discuss the history of and complications associated with bicuspid valvuloaortopathy. In this interview, Hector I. Michelena, MD, FACC and W.