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The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter AorticValve Implantation (TAVI) versus Surgical AorticValve Replacement (SAVR) in patients with severe aorticvalve stenosis (AS) at lower surgical risk.
The diagnostic coronary angiogram identified only minimal coronary artery disease, but there was a severely calcified, ‘immobile’ aorticvalve. Aortic angiogram did not reveal aortic dissection. If you see this, you should Doppler the valve. Aorticvalve surgery as an emergency procedure.
While left ventricular (LV) systolic function is preserved, right ventricular dysfunction (RVD) and consecutive LV underfilling may contribute to low-flow and reduced stroke volume index, and to adverse outcomes following transcatheter aorticvalve implantation (TAVI).
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