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60 or Younger? A 'Wake Up Call' for Mechanical Aortic Valve Replacement

Med Page Today

(MedPage Today) -- LOS ANGELES -- Survival outcomes favored mechanical valves for isolated surgical aortic valve replacement (SAVR) for people until age 60, after which a tissue valve may start to have an advantage, according to a large registry.

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TAVI Matches SAVR in Lower Risk Aortic Valve Patients: 10 year outcomes

Cardiology Update

The NOTION trial, a pioneering study, sought to compare the long-term clinical and bioprosthesis outcomes of Transcatheter Aortic Valve Implantation (TAVI) versus Surgical Aortic Valve Replacement (SAVR) in patients with severe aortic valve stenosis (AS) at lower surgical risk.

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New Study Suggests that Amyloid Contributes to Calcific Aortic Valve Disease Development

DAIC

Getty Images milla1cf Fri, 06/07/2024 - 15:10 June 7, 2024 — Calcific aortic valve disease (CAVD) is the major heart valve disease that afflicts nearly 10 million patients globally with an annual mortality exceeding 100,000, and the numbers continue to rise.

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Rare genetic variants linked to bicuspid aortic valve disease in young adults identified

Medical Xpress - Cardiology

Genetic variants linked to a rare form of bicuspid aortic valve disease that affects young adults and can lead to dangerous and potentially life-threatening aortic complications have been identified by researchers at UTHealth Houston.

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Aortic Valve Replacement for Asymptomatic Severe Aortic Stenosis

JAMA Cardiology

This Viewpoint advocates for prompt aortic valve replacement (rather than clinical surveillance) as the default strategy for patients with asymptomatic severe aortic stenosis.

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Use of Anticoagulant Drug after Aortic Valve Replacement Lowers Mortality Risk, Mayo Clinic Study Finds

DAIC

milla1cf Tue, 12/12/2023 - 07:00 December 12, 2023 — Patients who received the anticoagulant drug warfarin after bioprosthetic aortic valve replacement had lower incidence of mortality and a decreased risk of blood clots, according to a retrospective study published in Mayo Clinic Proceedings.

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Sarcopenia and aortic valve disease

Heart BMJ

Valvular heart disease, including calcific or degenerative aortic stenosis (AS), is increasingly prevalent among the older adult population. Over the last few decades, treatment of severe AS has been revolutionised following the development of transcatheter aortic valve replacement (TAVR).