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Intracranial atherosclerotic stenosis is a leading cause of stroke with a significant risk of recurrent ischemic events despite aggressive medical management. However, 3 percutaneous angioplasty and stenting randomized trials showed negative or neutral results. Stroke, Volume 56, Issue 4 , Page e114-e118, April 1, 2025.
Asymptomatic high-grade carotid stenosis is an important therapeutic target for stroke prevention. Advances in treatments against atherosclerosis have driven down the rates of stroke in patients managed without revascularization.
IntroductionVertebral artery stenting represents a viable option in treating symptomatic vertebral artery atherosclerotic stenosis. We included articles reporting patients > 18 years old with symptomatic extracranial vertebral artery stenoses due to atherosclerosis treated with stenting (with or without angioplasty).
Most neurointerventionalists (91%) diagnose ICAS‐LVO after a continued or recurrent occlusion or by the presence of fixed focal stenosis after multiple mechanical thrombectomy attempts. Most respondents (86%) preferred acute treatment of ICAS‐LVO with rescue stenting (RS)±angioplasty.
IntroductionIntracranial atherosclerosis‐related large vessel occlusion (ICAS‐LVO) is a common cause of failed mechanical thrombectomy (MT) in acute ischemic stroke (AIS) [1]. Treatment of ICAS‐LVO with rescue stenting and/or angioplasty has shown promising outcomes, but diagnosing ICAS‐LVO during MT can be challenging [2, 3].
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