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Chinese patent medicine tongxinluo capsule as a supplement to treat chronic coronary syndromes: a GRADE-assessed systematic review and meta-analysis of randomized controlled trials

Frontiers in Cardiovascular Medicine

Evidence supports the use of TXL plus WM for reducing angina frequency [SMD 2.50, 95% CI (3.53, 1.48)], improving seattle angina questionnaire scores (P<0.05), decreasing nitroglycerin dose [SMD 1.63, 95% CI (2.26, 1.00)], and shortening angina duration [MD 1.50min/once, 95% CI (1.98, 1.02)].

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Sildenafils effectiveness in the primary coronary slow flow phenomenon: a pilot randomised controlled clinical trial

Open Heart

Background On the one hand, the primary coronary slow flow phenomenon (CSFP) can cause recurrence of chest pain, prompting medical examinations and further healthcare costs, while on the other hand, it can lead to myocardial infarction, ventricular arrhythmia and sudden cardiac death.

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Ninerafaxstat Well-Tolerated and Safe for Nonobstructive Hypertrophic Cardiomyopathy

DAIC

It causes the heart muscle to become stiff and thick, making it harder for the heart to pump blood properly and increasing the risk of sudden cardiac death. HCM is the most common genetic heart disease worldwide and is estimated to affect 1 in 500 people.

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Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

21-23 hsCRP is nonspecific inflammatory marker and an acute phase reactant that predicts the likelihood of a heart attack, stroke, peripheral artery disease and sudden cardiac death among healthy individuals with no history of CV disease, and recurrent events and death in patients with known ASCVD.22

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The “open data” movement runs aground on FOURIER

Dr. Anish Koka

🤨 20% reduction in traditional MACE (CV death, MI, stroke) 4:49 AM ∙ Jan 14, 2023 13 Likes 2 Retweets But the primary endpoint here was a composite endpoint of cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina, or coronary revascularization.

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Why many Ischemic VTs are not abolished by revascularization ?

Dr. S. Venkatesan MD

There is a problem here too ,even critical Ischemia with high grade unstable angina rarely trigger a VT but STEMI seems to have the exclusive rights to trigger it , by its ability to produce acute transmural ischemia. Even here, it is the associated factors, like hypoxia or acidosis are the triggers which of course are resultant of Ischemia.

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Surgical outcomes in adolescents and adults with anomalous aortic origin of a coronary artery

Frontiers in Cardiovascular Medicine

BackgroundAnomalous aortic origin of a coronary artery (AAOCA) is associated with an increased risk of myocardial ischemia and sudden cardiac death. The incidence of postoperative cardiac-type symptoms (angina, syncope or dyspnea) was higher in ALCA-R patients compared to ARCA-L patients.

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