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Recurrent polymorphic ventricular tachycardia without chest pain: an unusual presentation of focal coronary artery spasm

The British Journal of Cardiology

Coronary artery spasm (CAS), or Prinzmetal angina, is a recognised cause of myocardial ischaemia in non-obstructed coronary arteries which typically presents with anginal chest pain. This case report describes an atypical presentation of CAS in a 68-year-old white British male with cardiovascular risk factors.

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Familial risk of vasospastic angina: a nationwide family study in Sweden

Open Heart

Objectives Vasospastic angina (VSA) is a complex coronary vasomotor disorder associated with an increased risk of myocardial infarction and sudden death. Despite considerable advances in understanding VSA pathophysiology, the interplay between genetic and environmental factors remains elusive.

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Ischemia with no obstructed coronary arteries and microvascular testing procedures: a review of utility, pharmacotherapy, and current challenges

Frontiers in Cardiovascular Medicine

Ischemia with no obstructive coronary arteries (INOCA) is an increasingly recognized condition in patients presenting with angina and positive stress tests but without significant coronary artery stenosis. The paper discusses a potential interference between vasodilators used in trans-radial access and coronary spasm testing.

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Lumbar disc herniation is an independent predictor of plaque burden in the patients with unstable angina

Frontiers in Cardiovascular Medicine

Methods In this study, a total of 212 patients (age 46–80 years) with unstable angina (UA) who underwent coronary angiography (CAG) in our hospital from January 2018 to July 2022 due to UA were included. LDH was found to be an independent risk factor for higher Gensini scores (OR = 2.38, P  < 0.01) by logistic analysis.

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A man in his 40s with 3 days of stuttering chest pain

Dr. Smith's ECG Blog

Distilling this case into its most salient components, a man with multiple risk factors for coronary disease is presenting with several days of chest pain and markedly elevated troponin with no other reason to explain the lab abnormality ( e.g. sepsis). This is WHY refractory angina should prompt immediate angiography.

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Polygenic risk score predicts all-cause death in East Asian patients with prior coronary artery disease

Frontiers in Cardiovascular Medicine

A pruning and thresholding method was used to calculate PRS of CAD and its 14 risk factors. Elastic-net Cox regression with 5-fold cross-validation was used to integrate these nine PRS models into a meta score, metaPRS, which performed well in stratifying patients at different risks for death ( P  < 0.0001).

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How High Blood Pressure Affects Your Heart and What You Can Do About It

MIBHS

This condition reduces blood flow to the heart, increasing the risk of angina (chest pain) and heart attacks. Coronary Artery Disease (CAD) : High blood pressure accelerates the development of CAD by promoting the buildup of plaques in the coronary arteries.