Frontiers in Cardiovascular Medicine

FEBRUARY 12, 2024

Introduction Coronary artery disease (CAD) is a highly heritable and multifactorial disease. Numerous genome-wide association studies (GWAS) facilitated the construction of polygenic risk scores (PRS) for predicting future incidence of CAD, however, exclusively in European populations.

Coronary Artery Disease 59

Coronary Artery Disease Risk Factors Myocardial Infarction Cholesterol 59

Frontiers in Cardiovascular Medicine

JULY 5, 2024

BackgroundVasospastic angina usually presents with intermittent episodes of chest pain. Subsequent invasive coronary angiography showed no obstructive epicardial coronary artery disease. She reported that she often experienced an abnormal smell sensation just prior to the event.

Angina 52

Angina Chest Pain Coronary Artery Disease Exercise 52

Circulation

OCTOBER 5, 2023

BACKGROUND:We investigated the usefulness of invasive coronary function testing to diagnose the cause of angina in patients with no obstructive coronary arteries.METHODS:Outpatients referred for coronary computed tomography angiography in 3 hospitals in the United Kingdom were prospectively screened. versus 50.9%,P<0.001).At

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Angina Coronary Artery Disease Circulation Hospital 40

Frontiers in Cardiovascular Medicine

MARCH 17, 2024

Background Refractory angina (RA) is a chronic condition characterized by the presence of debilitating angina symptoms due to established reversible ischemia in the presence of obstructive coronary artery disease (CAD).

Angina 64

Angina Quality of Life Coronary Artery Disease Ischemia 64

Open Heart

OCTOBER 1, 2024

Background The prognosis of myocardial ischaemia with no obstructive coronary artery disease (INOCA) and its underlying vasomotor disorders, vasospastic angina (VSA) and microvascular angina (MVA), is not well defined.

Coronary Artery Disease 52

Coronary Artery Disease Outcomes Angina Myocardial Infarction 52

DAIC

MAY 2, 2024

Results from the open label roll-in cohort of patients having chronic myocardial ischemia with refractory angina showed an average increase in exercise tolerance of 107 seconds and an average of 82% reduction in angina episodes at the primary six-month follow-up endpoint compared to before receiving the study treatment.

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Ischemia Angina Heart Failure Outcomes 95

Open Heart

JULY 24, 2023

Introduction Current guideline recommend functional imaging for myocardial ischaemia if coronary CT angiography (CTA) has shown coronary artery disease (CAD) of uncertain functional significance. However, diagnostic accuracy of selective myocardial perfusion imaging after coronary CTA is currently unclear.

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Coronary Artery Disease Angina Article Research 52

Nature Reviews - Cardiology

APRIL 24, 2024

Nature Reviews Cardiology, Published online: 25 April 2024; doi:10.1038/s41569-024-01033-x Findings from the ORBITA-COSMIC trial show that treatment of patients with stable coronary artery disease using a coronary sinus reducer improves angina symptoms but does not increase transmural myocardial perfusion.

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Angina Coronary Artery Disease 40

Open Heart

APRIL 4, 2022

Objective Given recent data on published diagnostic accuracies, this study sought to determine the most cost-effective diagnostic strategy for detection of significant coronary artery disease (CAD) in stable angina patients using invasive coronary angiography (ICA) and fractional flow reserve (FFR) as the reference standard.

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Angina Coronary Artery Disease 52

Circulation

JUNE 30, 2024

Circulation, Volume 150, Issue 1 , Page e3-e4, July 2, 2024.

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Coronary Artery Disease Angina Article Circulation 49

Journal of the American Heart Association

DECEMBER 1, 2023

BackgroundCoronary computed tomography angiography is increasingly used as the first‐line test for suspected coronary artery disease. The overall mortality, cardiac deaths, myocardial infarctions, and hospitalizations for unstable angina were acquired from national registry data for 1 to 10 years of follow‐up (median, 4 years).

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Coronary Artery Disease Myocardial Infarction Angina Hospital 40

Circulation: Cardiovascular Interventions

JANUARY 15, 2024

BACKGROUND:The underlying mechanisms responsible for the clinical benefits following coronary sinus narrowing and pressure elevation remain unclear. Secondary end points included changes in coronary flow reserve and the resistive resistance ratio values.

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Angina Coronary Artery Disease Physiology Cardiovascular Interventions 40

Circulation

DECEMBER 27, 2023

Circulation, Volume 149, Issue 1 , Page 24-27, January 2, 2024.

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Coronary Artery Disease Angina Circulation 45

NOVARAD

APRIL 19, 2023

Coronary artery disease (CAD) is the most common type of heart disease and the leading cause of death globally: one in four people lose their lives to CAD annually. Coronary arteries provide the heart with the oxygen-rich blood that it needs to function, carrying away oxygen-depleted blood.

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Coronary Artery Disease Heart attacks Heart Attack Angina 52

DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3

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Cardiovascular Disease Heart attacks Heart Attack Coronary Artery Disease 111

Coronary Artery Disease Journal

JUNE 3, 2024

Objectives There are few reports regarding the prognosis in patients with obstructive coronary artery disease (OCAD) and vasospastic angina (VSA). This study investigated the clinical characteristics and clinical outcomes in patients with VSA and OCAD, especially regarding provoked spasm phenotypes and sites.

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Stenosis Angina Chest Pain Coronary Artery Disease 40

Open Heart

MAY 2, 2023

We aimed to determine whether different strategies to manage suspected stable angina affected medium-term cardiovascular event rates and patient-reported quality of life (QoL) measures. 12) Questionnaire and EuroQol-5 Dimension Questionnaire were recorded.

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Chest Pain Quality of Life Angina Coronary Artery Disease 52

Dr. Paddy Barrett

DECEMBER 5, 2023

Subscribe now Stenting stable coronary artery disease has not been convincingly proven to reduce the risk of future heart attacks or death 1. Whether stenting a narrowed coronary artery improves symptoms such as chest pain (angina) or shortness of breath is a very different question. What About Symptoms?

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Stents Stent Angina Heart attacks 59

Open Heart

AUGUST 21, 2023

The incidence of clinical endpoints (cardiovascular (CV) death, AMI, unstable angina with urgent revascularisation and stroke; bleeding; and all-cause mortality) was analysed. Data were collected at baseline and every 6 months for 24 months. to 1.00, p=0.04); ERR=0.84 (95% CI, 0.78 to 0.92, p<0.001); ERR=0.86 (95% CI, 0.81

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Myocardial Infarction Angina Outcomes Coronary Artery Disease 52

DAIC

APRIL 5, 2024

With the addition of Shockwave, Johnson & Johnson will expand its MedTech cardiovascular portfolio into two of the highest-growth, innovation-oriented segments of cardiovascular intervention – coronary artery disease (CAD) and peripheral artery disease (PAD). The Reducer System has a growing commercial presence.

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Cardiovascular Interventions Technology Innovation Angina 105

Heart BMJ

JANUARY 29, 2024

Assessment of patients presenting for the first time with suspected coronary artery disease (CAD) remains cumbersome with multiple diagnostic options. Invasive coronary angiography as a first-line test tends to be reserved for patients with high probability of CAD (typical angina symptoms with risk.

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Exercise Chest Pain Coronary Artery Disease Angina 40

Journal of Cardiovascular Pharmacology

JANUARY 8, 2024

The favorable efficacy of CHM was primarily presented on five main conditions, coronary artery disease, hypertension, heart failure, restenosis, and angina pectoris. CHM, with or without conventional treatment, showed a consistent beneficial effect in various cardiovascular diseases.

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Cardiovascular Disease Coronary Artery Disease Angina Heart Failure 40

Cardiometabolic Health Congress

NOVEMBER 22, 2024

Personalized Cardiometabolic Care TRANSFORM Program for Coronary Artery Disease (CAD) : The TRANSFORM program focuses on atherosclerosis-based care strategies rather than traditional risk-based approaches. The trial highlights the importance of reevaluating and optimizing thrombolytic therapies for better patient outcomes.

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Blood Pressure Obesity Preserved Ejection Fraction Coronary Artery Disease 59

Circulation

NOVEMBER 11, 2024

Patients usually have a normal life expectancy unless other structural heart diseases are present. Introduction:Dextrocardia is a rare congenital condition where the heart's apex points to the right, with an incidence of about 0.01%. His vital signs were normal, and the physical examination was unremarkable.

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Coronary Artery Disease Angioplasty Anatomy Angina 40

All About Cardiovascular System and Disorders

APRIL 13, 2024

This highlights the need for serial ECGs in acute coronary syndrome as initial ECGs may be near normal even in those with severe disease. Classical electrocardiographic pattern in left main coronary artery disease is ST elevation in aVR with extensive ST depression in other leads, most prominent in I, II and V4-V6.

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Stenosis Coronary Artery Bypass Graft Coronary Artery Disease Document 52

Circulation

NOVEMBER 11, 2024

Background:The impact of antianginal therapies on the health status of coronary artery disease (CAD) patients who have undergone coronary revascularization has not been extensively researched. Methods:We analyzed data from 1,556 patients enrolled in the GREAT Disease Registry Study (Clinicaltrial No.

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Outcomes Coronary Artery Disease Angina Circulation 40

Circulation

NOVEMBER 11, 2024

Introduction:Inflammation plays an important role in the pathogenesis of coronary artery disease and Acute Coronary Syndrome (ACS). Types of ACS include stable angina 5.3% (n=8), unstable angina 24% (n=36), NSTEMI 28.7% (n=43), and STEMI 24% (n=36). The mean age of patients was 57.68 (SD= 11.19) years.

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Angina Coronary Artery Disease Biomarkers Atherosclerosis 40

Dr. Prateek Bhatnagar

AUGUST 21, 2023

Patient Mr. Paras Ram was having unstable angina (chest pain at rest) at his native place. Coronary angiography showed tight left main coronary artery disease with severe triple vessel disease. All his coronary arteries were heavily calcified.

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Open-Heart Surgery Atrial Fibrillation Chest Pain Coronary Artery Disease 52

Cardiology Update

APRIL 9, 2024

The primary endpoint consisted of a composite of all-cause mortality, MI, stroke, coronary revascularization, or hospitalization for unstable angina. The results advocate for considering PCI as a treatment option for such plaques, potentially expanding the indications for PCI in coronary artery disease management.

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Myocardial Infarction Angina Aortic valve Coronary Artery Disease 52

MIBHS

OCTOBER 15, 2024

For example, if a coronary artery becomes blocked due to plaque buildup (a condition known as coronary artery disease), the heart muscle may not receive enough oxygen, leading to chest pain (angina) or, in more severe cases, a heart attack. Any interruption in this process can result in serious consequences.

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Circulation Heart attacks Heart Attack Chest Pain 52

Dr. Anish Koka

MAY 16, 2023

Diamond and Forrester accomplished this by first establishing the prevalence of coronary artery disease based on how clinically likely patients with chest pain symptoms were found to have coronary disease based on a coronary angiogram. Thanks for reading Dr. Anish Koka's Newsletter!

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Chest Pain Coronary Artery Disease Cancer Heart attacks 52

Circulation

NOVEMBER 11, 2024

Coronary angiography revealed a tortuous and extremely aneurysmal RCA, as well as multivessel coronary artery disease (mvCAD) involving LAD, D1, LCx, OM1. Multislice CT angiography further characterized the RCA, which extends to the coronary sinus (CS) distally forming a coronary cameral fistula (CCF).

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Coronary Artery Bypass Graft ACE Inhibitor Coronary Angiogram Aneurysm 40

Dr. Smith's ECG Blog

DECEMBER 7, 2023

I quickly reviewed the patient’s records and saw that she was a 53 year old woman with a history of BMI 40, but no other identifiable risk factors for coronary artery disease. The absence of risk factors for coronary artery disease does not mean a patient is not at risk for OMI.

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SCAD Ischemia Coronary Artery Disease Cardiomyopathy 111

Dr. S. Venkatesan MD

OCTOBER 29, 2024

Aggressive lipid-lowering therapy compared with angioplasty in stable coronary artery disease. Reference Pitt B, Waters D, Brown WV, van Boven AJ, Schwartz L, Title LM, Eisenberg D, Shurzinske L, McCormick LS. Atorvastatin versus Revascularization Treatment Investigators. N Engl J Med. 1999 Jul 8;341(2):70-6. PMID: 10395630.

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Angioplasty Coronary Artery Disease Plaque Angina 52

Coronary Artery Disease Journal

DECEMBER 10, 2023

Background Cardiac 15O-water PET is a noninvasive method to evaluate epicardial and microvascular dysfunction and further quantitate absolute myocardial blood flow (MBF).

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Angina Research 40

Dr. Smith's ECG Blog

DECEMBER 6, 2024

Angiogram: Severe two-vessel coronary artery disease of a left dominant system including 70 to 80% stenosis involving the distal left main/bifurcation. Case continued Troponins over 26 hours, from right to left : Echocardiogram: Mild concentric left ventricular wall thickening, normal cavity size, and normal systolic function.

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Coronary Artery Bypass Graft Ischemia Stenosis Chest Pain 104

The British Journal of Cardiology

APRIL 16, 2024

We present the cumulative percutaneous coronary intervention (PCI) data of all comers (stable angina and acute coronary syndromes [ACS]) who presented to Hadi Clinic between January 2018 and December 2020.

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Outcomes Cardiogenic Shock Angina STEMI 40