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Given her lack of risk factors for coronary disease, and the fact that she was a 53 year old woman with compatible history and echo findings, stress cardiomyopathy rose to the top of my differential. Of course, stress cardiomyopathy is a diagnosis of exclusion. This proves effective treatment of the recurrent ischemia.
This appears to be a classic Wellens' ECG, Pattern A, with terminal T-wave inversion in V2-V4, preserved R-waves, and it appears to be Wellens' syndrome, as it occurred after resolution of typical angina pain. When this happens, troponins are negative, there is no wall motion abnormality, and it is true unstable angina.
ET Main Tent (Hall B1) This session offers more insights from key clinical trials presented at ACC.24 24 and find out what it all means for your patients. 12:15 p.m.
Subsequent testing supported the presumption of apical cardiomyopathy as the cause of this patient's sustained VT. CT coronary angiogram showed no obstructive coronary disease. Today's case is illustrative because it shows how high troponin may rise despite the absence of acute coronary occlusion! (
by making it clear to everyone that this is NOT an EKG that one sees with takotsubo cardiomyopathy. Takotsubo is a sudden event, not one with crescendo angina. The impact of ST-segment elevation on the prognosis of patients with Takotsubo cardiomyopathy. I need to innoculate you against the subsequent opinions below.
Now you have ECG and troponin evidence of ischemia, AND ventricular dysrhythmia, which means this is NOT a stable ACS. It they are static, then they are not due to ischemia. This is better evidence for ischemia than any other data point. Again, cath lab was not activated. What does this troponin level mean? Int J Cardiol.
True MINOCA was defined by evidence of ischemia or infarction on CMR. MACEs included allcause death, recurrent myocardial infarction, stroke, heart failure, atrial fibrillation, and angina pectoris. LA and left ventricular strains varied by pathogenesis, with the lowest strain in patients with cardiomyopathy.
The study presents a case of INOCA attributed to CMVD in a 53-year-old male patient experiencing exertional angina, despite the absence of significant coronary artery stenosis on angiography. While an MYH7 variant was also detected, its clinical relevance was ruled out due to the family's absence of associated cardiomyopathy phenotypes.
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