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14,15 Similarly, the NLRP3 inflammasome has been implicated in pathogenesis as it leads to the activation of proinflammatory cytokines triggering robust proinflammatory signaling through interleukin-6 (IL-6) and inducing production of C-reactive protein (CRP), a biomarker for inflammation.16 22 In general, hsCRP values above 2.0 N Engl J Med.
Not surprisingly, a dataset of coronary angiograms and chest pain syndromes showed that the more classic the chest pain syndrome was, the higher the likelihood that angiographic coronary disease was present. Atypical angina is classified as having any two of the three symptoms, and non-anginal pain any one of the three symptoms.
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