Abstract 4140212: Cardiac Electrophysiologic Response to Single-dose AUX-001, a Once-Daily Extended-Release Nicorandil in Development for Chronic-stable Angina in Adult Healthy Volunteers under Fasting and Fed Conditions
Circulation
NOVEMBER 11, 2024
Findings also confirm previous healthy volunteer trials with IR NIC highlighting no tendency promoting arrhythmia in normal, non-ischemic myocardium. While EU labeling and trials highlight no proarrhythmogenicity lack of recent data remains along with prior reports of potential impact of IR NIC on EKG patterns.
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