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Background Aortic stenosis is a life-limiting condition for which transcatheter aorticvalve implantation (TAVI) is an established therapy. Subsidiary outcomes included patient angina and breathlessness scores. CAD at the time of TAVI also did not alter breathlessness or angina scores before/after TAVI (p>0.05).
Background and aims Randomised controlled trials comparing transcatheter aorticvalve replacement (TAVR) and surgical aorticvalve replacement (SAVR) were performed in highly selected populations and data regarding long-term secondary complications beyond mortality are scarce. to 1.43), 3 years (HR 1.45; 95% CI 1.28
ET Murphy Ballroom 4 ACC.24 24 planners note that attendees can gain insights from key clinical trials presented at ACC.24 24 and how those may impact clinical practice and patient care in this deep dive clinical trial session.
Prior transapical transcatheter aorticvalve replacement (TA-TAVR) may complicate the procedure and is therefore considered a relative contraindication.
Left ventricular afterload reduction is essential to decrease the trans-se ptal pressure gradient and thus decrease shunt volume, making a larger proportion of the blood flow from the left ventricle through the aorticvalve.
SMART 4 ( NCT04722250 ) studied patients with severe aortic stenosis and a small aortic annulus who underwent transcatheter aorticvalve replacement (TAVR). A total of 716 patients underwent TAVR with either a self-expanding supraannular valve or a balloon-expandable valve. in the medical therapy group.
Larger shunt volume means less blood exiting the left ventricle through the aorticvalve and lower cardiac output. The pressure gradient in this case was significant indicating that the defect is rather small. The larger the size of the defect the larger the shunt.
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