Remove Aneurysm Remove Ischemia Remove Outcomes
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Abstract WP35: Neutrophil Extracellular Traps As a Biomarker for Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage

Stroke Journal

Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH). Following SAH, neutrophils cause vascular occlusion via neutrophil extracellular traps (NETs) and NETs have been identified as a therapeutic target to prevent delayed cerebral ischemia in mice (DCI) with SAH. nucleosome.

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Is this acute STEMI? LV Aneurysm? Would you give Thrombolytics?

Dr. Smith's ECG Blog

There were many comments that it was too late for thrombolytics or that this signified an LV aneurysm, not acute MI. See my formula for differentiating anterior LV aneurysm (that is to say, persistent ST elevation after old MI) from acute anterior STEMI. See my answer below. This is my response: "This is definitely acute or subacute.

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Comparison of Angiographic Outcomes of Woven EndoBridge and Balloon?Assisted Coiling for the Treatment of Ruptured Wide?Necked Aneurysms: A Multicentric Study

Stroke: Vascular and Interventional Neurology

BACKGROUNDThe optimal endovascular approach for acutely ruptured wide‐neck intracranial aneurysms remains uncertain, and the use of stent‐assisted coiling or flow diversion is controversial due to antiplatelet therapy requirements and potential risks. Stroke: Vascular and Interventional Neurology, Ahead of Print. Of the patients, 60.5%

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Abstract 039: Angiographic Outcomes of Woven EndoBridge and Balloon?Assisted Coiling for the Treatment of Ruptured Wide?Necked Aneurysms

Stroke: Vascular and Interventional Neurology

IntroductionThe optimal endovascular approach for wide‐neck intracranial aneurysms (IAs) during the acute phase of bleeding remains uncertain, and the use of stent‐assisted coiling or flow diversion is controversial due to antiplatelet therapy requirements and potential risks (1, 2). Of the patients, 60.5%

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Abstract 114: LACROSSE Trial: Lumbar Drainage Compared to External Ventricular Drainage in Aneurysmal Subarachnoid Hemorrhage, a Randomized Control Trial

Stroke Journal

Introduction:Delayed cerebral ischemia (DCI) is a leading cause of morbidity and mortality in aneurysmal subarachnoid hemorrhage (aSAH). The primary outcome was DCI, defined as an exclusionary change in GCS or new, none-treatment related infarcts on imaging. Stroke, Volume 55, Issue Suppl_1 , Page A114-A114, February 1, 2024.

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Abstract WMP112: Neutrophil Extracellular Traps Occlude the Cerebrovasculature Causing Delayed Cerebral Ischemia After Subarachnoid Hemorrhage in Mice

Stroke Journal

Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH). In this study, our hypothesis was that NETs cause vascular occlusion leading to delayed cerebral ischemia (DCI) and worse outcome after SAH. However, degrading NETs only marginally improved outcomes.

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Abstract WP152: Association Between Cerebrospinal Fluid Interleukin-6 Levels and Cerebral Autoregulation After Aneurysmal Subarachnoid Hemorrhage

Stroke Journal

Introduction:Elevated levels of Interleukin-6 (IL-6) levels in cerebrospinal fluid (CSF) have been correlated with delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). Further studies are needed to validate findings and refine MAP management for improved outcomes in aSAH patients.