Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionThe Pipeline Embolization Device (PED) is commonly used for intracranial aneurysm treatment. While its effectiveness for certain types of aneurysms is well‐established, its efficacy for saccular aneurysms remains debatable. The primary endpoint was angiographic complete aneurysm occlusion at long‐term (≥ 12 mo.)

Aneurysm 40

Aneurysm Outcomes Embolism Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Background:While predictors of seizure in aneurysmal subarachnoid hemorrhage (aSAH) patients have been explored, predictors for seizure in patients with angiogram-negative non-perimesencephalic SAH (an-NPSAH) are less understood. Neither intracerebral hemorrhage nor aneurysm securement modality was associated with seizure.

Aneurysm 40

Aneurysm Hemorrhage Academic Hospital 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionIntracranial Aneurysm results from enlargement in the wall of a blood vessel in the brain, especially in the circle of Willis. It represents a high mortality and morbidity rate due to its risk of rupture causing Sub Arachnoid Hemorrhage which is a dangerous and life‐threatening condition. in Kenya and 44.4% in Nigeria.

Aneurysm 40

Aneurysm Hemorrhage Risk Factors Outcomes 40

Stroke: Vascular and Interventional Neurology

FEBRUARY 15, 2024

BACKGROUNDThe optimal endovascular approach for acutely ruptured wide‐neck intracranial aneurysms remains uncertain, and the use of stent‐assisted coiling or flow diversion is controversial due to antiplatelet therapy requirements and potential risks. P= 0.180) and hemorrhagic events (WEB: 3.8% P= 0.180) and hemorrhagic events (WEB: 3.8%

Aneurysm 40

Aneurysm Outcomes Hemorrhage Stent 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Pregnancy is a risk factor for subarachnoid hemorrhage (SAH). We aim to better understand this risk and its impact on in-hospital outcomes over a longitudinal time period in a large population based sample.Methods:We analyzed the 2000-2019 National Inpatient Sample, selecting for aneurysmal SAH (aSAH).

Inpatient 40

Inpatient Aneurysm Hemorrhage Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Both anticoagulants can be used intraoperatively and postoperatively for DVT prophylaxis in patients undergoing subarachnoid hemorrhage (SAH) treatment. Patients from both groups were assessed for baseline clinical characteristics, comorbidities, interventions, complications, and outcomes.

Hemorrhage 40

Hemorrhage Aneurysm Outcomes Thrombosis 40

Stroke Journal

JANUARY 30, 2025

Introduction:Flow diversion (FD) is a minimally invasive treatment for unruptured intracranial aneurysms (UIA) and is often preferred over open cerebrovascular surgery; however, FD patients are at risk of post-procedural stroke and hemorrhage. Initial hospitalization outcomes were assessed. to 2.51], p=0.005; Figure 3).

Aneurysm 40

Aneurysm Hospital Hemorrhage Outcomes 40

Stroke Journal

JANUARY 30, 2025

Introduction:Early brain injury (EBI), a complex collection of pathophysiological processes occurring within 72 hours aneurysmal subarachnoid hemorrhage (aSAH), is the key link connecting the initial event to the delayed and long-term complications. Stroke, Volume 56, Issue Suppl_1 , Page ATMP4-ATMP4, February 1, 2025.

Aneurysm 40

Aneurysm Hemorrhage Biomarkers Stroke 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Impact of race on outcomes in the treatment of intracranial aneurysm (IA) remains unclear. The primary outcome was 90-day mRS 0-2. The primary outcome in Hispanic patients was significantly lower than White patients (adjusted odds ratio [aOR] 0.36, 95% CI, 0.23-0.56,P< P< 001).

Aneurysm 40

Aneurysm Outcomes Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionFlow diversion (FD) has emerged as an effective treatment option for intracranial aneurysms (IAs). This study aimed to investigate the outcomes of FD for these aneurysms.MethodsA retrospective analysis of a multicentric observational registry was performed between 2014 and 2022. interquartile range [IQR]: 52.8‐65.3

Aneurysm 40

Aneurysm Circulation Hemorrhage Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionThe optimal endovascular approach for wide‐neck intracranial aneurysms (IAs) during the acute phase of bleeding remains uncertain, and the use of stent‐assisted coiling or flow diversion is controversial due to antiplatelet therapy requirements and potential risks (1, 2). Of the patients, 60.5%

Aneurysm 40

Aneurysm Outcomes Hemorrhage Stent 40

Stroke Journal

FEBRUARY 1, 2024

Our study aims to describe the trends and outcomes of patients with Subarachnoid Hemorrhage (SAH) using a Nationwide Inpatient Sample (NIS) database.Methods:We examined the 2016-2020 NIS database, focusing on patients aged 18 years and older with a primary SAH discharge diagnosis. years with 72,650 (61.0%) being female.

COVID-19 40

COVID-19 Hemorrhage Outcomes Inpatient 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionDue to the relative rarity of unruptured intracranial aneurysms (UIA) in the pediatric population, evidence regarding treatment modalities and clinical outcomes remains limited. days, p < 0.001), and lower rates of ischemic or hemorrhagic procedural‐related complications (1% vs. 4%, p = 0.010).ConclusionA

Pediatrics 40

Pediatrics Aneurysm Outcomes Inpatient 40

Stroke Journal

FEBRUARY 1, 2024

Background:Studies describing outcomes of subarachnoid hemorrhage (SAH) in children are sparse. 320 patients (24.4%) were treated endovascularly and 480 (36.6%) were treated via open surgical approach to treat vascular pathologies (AV malformations, dural AV fistulas, and aneurysms). Median length of hospitalization was 9.7

Pediatrics 40

Pediatrics Hemorrhage Outcomes Hospital 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionTo provide our single‐institution experience and outcome data with the WEB device in 51 patients treated for ruptured and unruptured intracranial aneurysms.MethodsOcclusion rates in a cohort of 51 patients treated with WEB were collected at time of procedure and at last follow‐up between the years 2019 and 2021.

Aneurysm 40

Aneurysm Embolism Hemorrhage Document 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Elevated levels of Interleukin-6 (IL-6) levels in cerebrospinal fluid (CSF) have been correlated with delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). Further studies are needed to validate findings and refine MAP management for improved outcomes in aSAH patients.

Aneurysm 40

Aneurysm Hemorrhage Ischemia Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2024

BACKGROUNDAneurysmal subarachnoid hemorrhage (aSAH) is a major source of morbidity and mortality, and its management has undergone foundational changes over thepast 2 decades. Patients undergoing surgery to secure an aneurysm were more severely ill through time yet experienced a stable hospital mortality rate.

Inpatient 40

Inpatient Hemorrhage Aneurysm Hospital 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Improved imaging modalities have led to an increased detection of intracranial aneurysms, many of which are small. Tiny size was defined as an aneurysm with a maximum dimension of ≤3 mm. Demographics, aneurysm characteristics and treatment safety were queried. The mean aneurysm width was 1.9

Aneurysm 40

Aneurysm Outcomes Inpatient Nursing 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionFlow diverters have demonstrated reliable safety and effectiveness for the treatment of selected anterior circulation intracranial aneurysms. However, posterior circulation aneurysms comprise around 10‐15% of all aneurysms, and they frequently present atypical morphological and anatomical characteristics.

Aneurysm 40

Aneurysm Circulation Hemorrhage Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Cerebral AVMs may manifest with new‐onset seizures or intraparenchymal (IPH) or subarachnoid hemorrhages (SAH). Life‐threatening bleeds may occur from the AVM nidus or associated aneurysms. Two large inflow aneurysms, felt to be the rupture site, projecting from the proximal left pericallosal artery were also demonstrated.

Aneurysm 40

Aneurysm Embolism Hemorrhage Hypertension 40

Stroke: Vascular and Interventional Neurology

SEPTEMBER 12, 2023

BackgroundUnruptured cerebral aneurysms (UCAs) have a relatively low prevalence of ≈3%, but detection can prevent devastating consequences of subarachnoid hemorrhage. There were a total of 36 true aneurysms with 4 cases of multiple aneurysms. Overall, the most common locations included internal carotid artery (42%).

Aneurysm 40

Aneurysm Hemorrhage Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionIntracranial aneurysms, both ruptured and unruptured, pose a significant risk to the general population. Cases of unruptured intracranial aneurysms (UIA) are estimated to affect roughly 3% of the general population and aneurysmal subarachnoid hemorrhage (aSAH) have an incidence of 8 to 9 people per 100,000.

Aneurysm 40

Aneurysm Embolism Stent Stents 40

Stroke Journal

FEBRUARY 1, 2024

Background:Cisternal score (CISCO), which is calculated based on quantification of blood clot in basal cisterns, has been shown to have good accuracy in predicting ventriculoperitoneal shunt requirement in patients with aneurysmal subarachnoid hemorrhage (aSAH).

Blood Clot 40

Blood Clot Aneurysm Hemorrhage Academic 40

Stroke Journal

JANUARY 18, 2024

Rigorous evidence generation with randomized controlled trials has lagged for aneurysmal subarachnoid hemorrhage (SAH) compared with other forms of acute stroke. Besides its lower incidence compared with other stroke subtypes, the presentation and outcome of patients with SAH also differ. Stroke, Ahead of Print.

Hemorrhage 40

Hemorrhage Aneurysm Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Evaluating the prognosis of aSAH patients who may be at risk of poor outcomes using grading systems is one way to make a better decision on treatment for these patients. Finally, we used logistic regression to identify factors associated with the 90-day poor outcome.Results:Of 415 patients, 32% had a 90-day poor outcome.

Hemorrhage 40

Hemorrhage Outcomes Aneurysm Hospital 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionSubarachnoid Hemorrhage (SAH) resulting from the spontaneous rupture of an aneurysm is a rare and highly debilitating condition. Despite its severity, patients with aneurysmal SAH remain understudied, particularly concerning the evaluation of the incidence and consequences of subsequent acute kidney injury (AKI).

Hemorrhage 40

Hemorrhage Aneurysm Cardiac Arrest Myocardial Infarction 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:The management of wide-necked internal carotid artery (ICA) aneurysms is technically challenging with established endovascular and microsurgical techniques that are limited by the associated morbidity and/or recurrence. Median aneurysm and neck size were 5.8 mm (IQR: 4.0-7.5)

Aneurysm 40

Aneurysm Stenosis Academic Stent 40

Stroke: Vascular and Interventional Neurology

DECEMBER 8, 2024

BACKGROUNDLocal angiotensin activity is thought to play a critical role in arterial wall homeostasis and remodeling, and impaired arterial wall integrity contributes to the pathogenesis of subarachnoid hemorrhage (SAH). The primary outcome was the subsequent development of nontraumatic SAH.

Hypertension 40

Hypertension Hemorrhage Pharmacology Aneurysm 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

After several patients in this series developed subarachnoid hemorrhage from a ruptured mycotic aneurysm, we proceeded to institute weekly cerebral angiography protocol. This detected moderate to severe vasospasm in 75%, and aneurysms in 58%, with the most common site being the basilar artery.

Aneurysm 40

Aneurysm Angioplasty Hemorrhage Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:The outcomes of mechanical thrombectomy (MT) for patients with acute ischemic stroke (AIS) caused by medium vessel occlusions (MeVOs) in different vessels remains unknown. The primary outcome measure was a 90-day modified Rankin score (mRS) 0-2. Stroke, Volume 55, Issue Suppl_1 , Page ATP219-ATP219, February 1, 2024.

Outcomes 40

Outcomes Stroke Strokes Aneurysm 40

Stroke Journal

FEBRUARY 1, 2024

Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH). In this study, our hypothesis was that NETs cause vascular occlusion leading to delayed cerebral ischemia (DCI) and worse outcome after SAH. However, degrading NETs only marginally improved outcomes.

Ischemia 40

Ischemia Hemorrhage Aneurysm Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Repeat CT head did not show stroke.ConclusionA Pseudo aneurysm is characterized by a rupture of the arterial wall and the formation of an aneurysmal sac by the adjacent structures while the sustaining artery remains intact. Two of seven symptomatic PSAs manifested with episodes of massive hemorrhage (3).

Aneurysm 40

Aneurysm Stroke Strokes Embolism 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionIndications for flow diversion for the treatment of cerebral aneurysms have increased remarkably in recent years.1 1 This has been particularly useful for aneurysms that are difficult to treat via endosaccular or open approaches, such as pseudoaneurysms.2

Embolism 40

Embolism Aneurysm Hemorrhage Stent 40

Stroke Journal

FEBRUARY 1, 2024

Background:Acute brain injuries, including aneurysmal subarachnoid hemorrhage (aSAH), ischemic stroke (IS), and traumatic brain injury (TBI), entail complex recovery processes involving brain plasticity and synaptic regeneration mechanisms. Results:Univariate analysis unveiled candidate molecules predictive of outcomes.

Biomarkers 40

Biomarkers Outcomes Aneurysm Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

This study aims to investigate the impact of the number of passes on the outcomes of patients who underwent failed MT.Methods:We used Data from the Stroke Thrombectomy and Aneurysm Registry (STAR) from 2013 to August 2023. Primary outcome was 90- day modified Rankin Scale (mRS) 0-2.

Stroke 40

Stroke Strokes Thrombolysis Aneurysm 40

Stroke Journal

FEBRUARY 1, 2024

Background:One of the keys to mitigating adverse outcomes of an ischemic or hemorrhagic stroke is timely access to a stroke center. For intracerebral hemorrhage, early intensive blood pressure lowering within 2 hours of onset improved outcomes.

Stroke 40

Stroke Strokes Hemorrhage Blood Pressure 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Despite comparable outcomes for different frontline techniques in mechanical thrombectomy (MT) for acute ischemic stroke (AIS), there are sparse data regarding if and when to switch techniques if the first pass is unsuccessful. 3.86, P = 0.002) and 90-day good clinical outcome (adjusted odds ratio 2.10, 95% CI: 1.15-3.85,

Circulation 40

Circulation Stroke Strokes Thrombolysis 40