Stroke Journal

FEBRUARY 1, 2024

Introduction:Delayed cerebral ischemia (DCI) is a leading cause of morbidity and mortality in aneurysmal subarachnoid hemorrhage (aSAH). There was no significant difference between the two arms with regards to admission characteristics, aneurysm location, treatment type, or total number of vasospasm treatments.

Aneurysm 40

Aneurysm Hemorrhage ICU Ischemia 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionAneurysmal subarachnoid hemorrhage (aSAH) accounts for about 10% of hemorrhagic strokes [1] and holds a high mortality and morbidity rate. [2, Head CT on arrival showed a diffuse subarachnoid hemorrhage, more prominent in the posterior fossa, and grade IV on the modified Fisher scale.

Hemorrhage 40

Hemorrhage Aneurysm Atrial Fibrillation Diabetes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Elevated levels of Interleukin-6 (IL-6) levels in cerebrospinal fluid (CSF) have been correlated with delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH). Stroke, Volume 55, Issue Suppl_1 , Page AWP152-AWP152, February 1, 2024.

Aneurysm 40

Aneurysm Hemorrhage Ischemia Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionIntracranial Aneurysm results from enlargement in the wall of a blood vessel in the brain, especially in the circle of Willis. It represents a high mortality and morbidity rate due to its risk of rupture causing Sub Arachnoid Hemorrhage which is a dangerous and life‐threatening condition. in Kenya and 44.4% in Nigeria.

Aneurysm 40

Aneurysm Hemorrhage Risk Factors Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Introductionintracranial dissecting aneurysm in pediatric age group is uncommon and very few studies are available comparing outcome following endovascular and surgery. years (range, 3–15 years), comprising 25% of all treated intracranial aneurysms in pediatric cases during the specified period.

Aneurysm 40

Aneurysm Pediatrics Outcomes Hemorrhage 40

Hypertension Journal

JANUARY 2, 2024

BACKGROUND:Multiple pathways and factors are involved in the rupture of intracranial aneurysms. The EGFR (epidermal growth factor receptor) has been shown to mediate inflammatory vascular diseases, including atherosclerosis and aortic aneurysm. Similarly, ER-stress inhibition also significantly decreased the rupture rate.

Aneurysm 45

Aneurysm Pharmacology Atherosclerosis Hemorrhage 45

Stroke Journal

FEBRUARY 1, 2024

Background:Cerebral vasospasm is a well-known complication after aneurysmal subarachnoid hemorrhage (aSAH) and occurs more commonly in younger patients. Stroke, Volume 55, Issue Suppl_1 , Page AWP139-AWP139, February 1, 2024.

Atherosclerosis 40

Atherosclerosis Aneurysm Hemorrhage Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionFlow diversion (FD) has emerged as an effective treatment option for intracranial aneurysms (IAs). Patients harboring distal aneurysms of the posterior circulation including the PICA, AICA, SCA, and PCA P2‐3 treated with FD were included. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.

Aneurysm 40

Aneurysm Circulation Hemorrhage Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Pregnancy is a risk factor for subarachnoid hemorrhage (SAH). We aim to better understand this risk and its impact on in-hospital outcomes over a longitudinal time period in a large population based sample.Methods:We analyzed the 2000-2019 National Inpatient Sample, selecting for aneurysmal SAH (aSAH).

Inpatient 40

Inpatient Aneurysm Hemorrhage Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Introduction18‐36% of all intracranial aneurysms are middle cerebral artery(MCA) bifurcation aneurysms. 1) MCA bifurcation aneurysms have been historically challenging to treat endovascularly given they often have complex morphology and wide necks. Final angiography revealed complete occlusion of the aneurysm.

Aneurysm 40

Aneurysm Embolism Hemorrhage Stenosis 40

Stroke: Vascular and Interventional Neurology

FEBRUARY 15, 2024

BACKGROUNDThe optimal endovascular approach for acutely ruptured wide‐neck intracranial aneurysms remains uncertain, and the use of stent‐assisted coiling or flow diversion is controversial due to antiplatelet therapy requirements and potential risks. P= 0.180) and hemorrhagic events (WEB: 3.8% versus BAC: 2.8%;P= versus BAC: 7.5%;P=

Aneurysm 40

Aneurysm Outcomes Hemorrhage Stents 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionCerebral aneurysms are a rare cause of headaches and visual symptoms. While most unruptured aneurysms are asymptomatic, when symptoms do occur, they are most often headaches, cranial nerve palsies, or bilateral temporal hemianopsia due to compression of surrounding nerves or the optic chiasm.

Aneurysm 40

Aneurysm Embolism Hemorrhage Hospital 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionFlow diverters have demonstrated reliable safety and effectiveness for the treatment of selected anterior circulation intracranial aneurysms. However, posterior circulation aneurysms comprise around 10‐15% of all aneurysms, and they frequently present atypical morphological and anatomical characteristics.

Aneurysm 40

Aneurysm Circulation Hemorrhage Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Cerebral AVMs may manifest with new‐onset seizures or intraparenchymal (IPH) or subarachnoid hemorrhages (SAH). Life‐threatening bleeds may occur from the AVM nidus or associated aneurysms. Two large inflow aneurysms, felt to be the rupture site, projecting from the proximal left pericallosal artery were also demonstrated.

Aneurysm 40

Aneurysm Embolism Hemorrhage Hypertension 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionThe Pipeline Embolization Device (PED) is commonly used for intracranial aneurysm treatment. While its effectiveness for certain types of aneurysms is well‐established, its efficacy for saccular aneurysms remains debatable. The primary endpoint was angiographic complete aneurysm occlusion at long‐term (≥ 12 mo.)

Aneurysm 40

Aneurysm Outcomes Embolism Hemorrhage 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Impact of race on outcomes in the treatment of intracranial aneurysm (IA) remains unclear. Data from 9 centers in the United States, Europe, and Asia for IA patients who undertook endovascular treatment (EVT) or microsurgical treatment (MST) between January 2016 and December 2020 were included for analysis.

Aneurysm 40

Aneurysm Outcomes Stroke Strokes 40

Journal of the American Heart Association

FEBRUARY 29, 2024

BackgroundDelayed cerebral ischemia represents a significant contributor to death and disability following aneurysmal subarachnoid hemorrhage. In murine studies (n=30), the endovascular perforation model was predominantly used, while rat studies primarily employed intracisternal blood injection to mimic subarachnoid hemorrhage.

Ischemia 40

Ischemia Hemorrhage Blood Pressure Aneurysm 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Both anticoagulants can be used intraoperatively and postoperatively for DVT prophylaxis in patients undergoing subarachnoid hemorrhage (SAH) treatment. This nationwide, multicenter, retrospective study provides valuable insights for clinicians on how to prevent and manage HIT in patients with subarachnoid hemorrhage.

Hemorrhage 40

Hemorrhage Aneurysm Outcomes Thrombosis 40

Stroke Journal

FEBRUARY 1, 2024

Background:There are conflicting data on temporal trends in subarachnoid hemorrhage (SAH) incidence and outcomes. Aneurysmal SAH (aSAH) was defined as those with culprit aneurysms; cases with no available vessel imaging were considered aSAH if the hemorrhage volume was “massive” or if the patient died rapidly after onset.

Hemorrhage 40

Hemorrhage Aneurysm Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

We present a case of subarachnoid hemorrhage (SAH) due to SCS lead migration into the subdural space.MethodsAn 81‐year‐old female patient with a past medical history of heart failure, atrial fibrillation and a mechanical mitral valve, presents with a severe headache and right hemiparesis.

Hemorrhage 40

Hemorrhage Aneurysm Atrial Fibrillation Bicuspid/Mitral 40

Stroke: Vascular and Interventional Neurology

SEPTEMBER 12, 2023

BackgroundUnruptured cerebral aneurysms (UCAs) have a relatively low prevalence of ≈3%, but detection can prevent devastating consequences of subarachnoid hemorrhage. There were a total of 36 true aneurysms with 4 cases of multiple aneurysms. Overall, the most common locations included internal carotid artery (42%).

Aneurysm 40

Aneurysm Hemorrhage Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

Our study aims to describe the trends and outcomes of patients with Subarachnoid Hemorrhage (SAH) using a Nationwide Inpatient Sample (NIS) database.Methods:We examined the 2016-2020 NIS database, focusing on patients aged 18 years and older with a primary SAH discharge diagnosis. years with 72,650 (61.0%) being female. to COVID 5.6 (p=0.0006).

COVID-19 40

COVID-19 Hemorrhage Outcomes Inpatient 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:Improved imaging modalities have led to an increased detection of intracranial aneurysms, many of which are small. Tiny size was defined as an aneurysm with a maximum dimension of ≤3 mm. Demographics, aneurysm characteristics and treatment safety were queried. The mean aneurysm width was 1.9

Aneurysm 40

Aneurysm Outcomes Inpatient Nursing 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionThe optimal endovascular approach for wide‐neck intracranial aneurysms (IAs) during the acute phase of bleeding remains uncertain, and the use of stent‐assisted coiling or flow diversion is controversial due to antiplatelet therapy requirements and potential risks (1, 2).

Aneurysm 40

Aneurysm Outcomes Hemorrhage Stents 40

Stroke Journal

FEBRUARY 1, 2024

Introduction:The management of wide-necked internal carotid artery (ICA) aneurysms is technically challenging with established endovascular and microsurgical techniques that are limited by the associated morbidity and/or recurrence. Median aneurysm and neck size were 5.8 mm (IQR: 4.0-7.5)

Aneurysm 40

Aneurysm Stenosis Academic Stents 40

Stroke Journal

JANUARY 18, 2024

Rigorous evidence generation with randomized controlled trials has lagged for aneurysmal subarachnoid hemorrhage (SAH) compared with other forms of acute stroke. Stroke, Ahead of Print. Besides its lower incidence compared with other stroke subtypes, the presentation and outcome of patients with SAH also differ.

Hemorrhage 40

Hemorrhage Aneurysm Stroke Strokes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionOsler‐Weber‐Rendu disease, also known as hereditary hemorrhagic telangiectasia (HTT), is a developmental vascular disease characterized by multiple arteriovenous malformations (AVMs) due to genetic defects in endothelial angiogenesis pathways. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.

Hemorrhage 40

Hemorrhage Aneurysm Pulmonary Embolism 40

Stroke Journal

FEBRUARY 1, 2024

Background:Studies describing outcomes of subarachnoid hemorrhage (SAH) in children are sparse. 320 patients (24.4%) were treated endovascularly and 480 (36.6%) were treated via open surgical approach to treat vascular pathologies (AV malformations, dural AV fistulas, and aneurysms). Median length of hospitalization was 9.7

Pediatrics 40

Pediatrics Hemorrhage Outcomes Inpatient 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionDue to the relative rarity of unruptured intracranial aneurysms (UIA) in the pediatric population, evidence regarding treatment modalities and clinical outcomes remains limited. days, p < 0.001), and lower rates of ischemic or hemorrhagic procedural‐related complications (1% vs. 4%, p = 0.010).ConclusionA

Pediatrics 40

Pediatrics Aneurysm Outcomes Inpatient 40

Stroke Journal

FEBRUARY 1, 2024

Subarachnoid hemorrhage (SAH), commonly caused by a ruptured aneurysm, carries a high rate of disability and death. Stroke, Volume 55, Issue Suppl_1 , Page ATP169-ATP169, February 1, 2024. Patients who survive the initial bleed continue to be at risk of secondary insults.

Hemorrhage 40

Hemorrhage Ischemia Aneurysm Stroke 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionSubarachnoid Hemorrhage (SAH) resulting from the spontaneous rupture of an aneurysm is a rare and highly debilitating condition. Despite its severity, patients with aneurysmal SAH remain understudied, particularly concerning the evaluation of the incidence and consequences of subsequent acute kidney injury (AKI).

Hemorrhage 40

Hemorrhage Aneurysm Cardiac Arrest Myocardial Infarction 40

Stroke Journal

NOVEMBER 28, 2023

Stroke, Ahead of Print.

Blood Pressure 75

Blood Pressure Aneurysm Hemorrhage Stroke 75

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

There is limited data on the influence of COVID‐19 on treatment and outcomes in patients with intracranial aneurysms. We aimed to investigate the impact of COVID‐19 on the overall complications, including ischemic stroke and subarachnoid hemorrhage (SAH) rates in patients treated for intracranial aneurysms (IAs).MethodsThis

COVID-19 40

COVID-19 Aneurysm Outcomes Inpatient 40

Stroke Journal

FEBRUARY 1, 2024

Neutrophils are reported to be critical mediators of to poor outcome after subarachnoid hemorrhage (SAH). Aneurysmal SAH patients who developed DCI had elevated markers of NETs compared to non-DCI patients. Stroke, Volume 55, Issue Suppl_1 , Page AWMP112-AWMP112, February 1, 2024. Similar findings were observed for PAD4 inhibition.

Ischemia 40

Ischemia Hemorrhage Aneurysm Outcomes 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Repeat CT head did not show stroke.ConclusionA Pseudo aneurysm is characterized by a rupture of the arterial wall and the formation of an aneurysmal sac by the adjacent structures while the sustaining artery remains intact. Two of seven symptomatic PSAs manifested with episodes of massive hemorrhage (3).

Aneurysm 40

Aneurysm Stroke Strokes Embolism 40

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page ATP242-ATP242, February 1, 2024. Introduction:Evaluating the prognosis of aSAH patients who may be at risk of poor outcomes using grading systems is one way to make a better decision on treatment for these patients.

Hemorrhage 40

Hemorrhage Outcomes Aneurysm Hospital 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

After several patients in this series developed subarachnoid hemorrhage from a ruptured mycotic aneurysm, we proceeded to institute weekly cerebral angiography protocol. This detected moderate to severe vasospasm in 75%, and aneurysms in 58%, with the most common site being the basilar artery.

Aneurysm 40

Aneurysm Angioplasty Hemorrhage Outcomes 40