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IntroductionFlow diversion (FD) has emerged as an effective treatment option for intracranial aneurysms (IAs). Patients harboring distal aneurysms of the posterior circulation including the PICA, AICA, SCA, and PCA P2‐3 treated with FD were included. interquartile range [IQR]: 52.8‐65.3 Complete occlusion was achieved in 78.1%
IntroductionFlow diverters have demonstrated reliable safety and effectiveness for the treatment of selected anterior circulation intracranial aneurysms. However, posterior circulationaneurysms comprise around 10‐15% of all aneurysms, and they frequently present atypical morphological and anatomical characteristics.
We present a case of a 22-month-old boy with a hypokinetic and thin-walled aneurysm of the left ventricle apex. Cardiac magnetic resonance imaging revealed an akinetic aneurysm of the LV apex with a full-wall ischemic scar. Determining the origin of the aneurysm is challenging.
Circulation, Ahead of Print. BACKGROUND:Despite reported racial disparities between Black and White adults in short-term outcomes after abdominal aortic aneurysmal intervention, there is a paucity of literature aimed at understanding long-term disparities. The cumulative incidence of the primary outcome was 72.9% (95% CI, 71.8%73.9%)
Circulation, Ahead of Print. Kawasaki disease (KD), an acute self-limited febrile illness that primarily affects children <5 years old, is the leading cause of acquired heart disease in developed countries, with the potential of leading to coronary artery dilation and coronary artery aneurysms in 25% of untreated patients.
Circulation, Ahead of Print. Aortic aneurysm and dissection are high-risk cardiovascular diseases without an effective cure. RNA-sequencing analysis was performed to recapitulate possible changes in the transcriptome profile of SNO-Septin2 in macrophages in aortic aneurysm and dissection.
Circulation, Volume 150, Issue Suppl_1 , Page A4123899-A4123899, November 12, 2024. Identified echocardiograms were reviewed to confirm IVMS aneurysms and exclude sinus of Valsalva aneurysms. The mean neck diameter of the aneurysm was 8.7 Patients with concurrent structural heart anomalies were excluded.
IntroductionBasilar‐tip aneurysm (BTA) is the most common aneurysm found in the posterior circulation, representing 5–8% of total intracranial aneurysms. For ruptured aneurysms, Adjuvant therapy (BAC or SAC) was used to treat larger dimension aneurysms compared to CE (p = 0.046). vs. 10.7%).
Steep intracranial pressure (ICP) rise constitutes a hallmark of aneurysmal subarachnoid hemorrhage (SAH). In the brain parenchyma, we observed minimal infiltration of circulating immune cells, consistent with the effects of aneurysm rupture. Stroke, Volume 56, Issue Suppl_1 , Page ATP397-ATP397, February 1, 2025.
IntroductionIntracranial aneurysms, both ruptured and unruptured, pose a significant risk to the general population. Cases of unruptured intracranial aneurysms (UIA) are estimated to affect roughly 3% of the general population and aneurysmal subarachnoid hemorrhage (aSAH) have an incidence of 8 to 9 people per 100,000.
Circulation, Volume 150, Issue Suppl_1 , Page A4120434-A4120434, November 12, 2024. There was near transmural late gadolinium enhancement (LGE) of the aneurysm and an associated 7 mm of MAD with posterior mitral valve prolapse (MVP). The scar and aneurysm that develop can serve as substrate for reentrant VA.
IntroductionRuptured aneurysmal SAH accounts up to 80% of nontraumatic SAH, with more than 80% located in the anterior circulation and a mortality rate upwards of 50%.1‐3 1,2,4–6 Despite this, EVT of intracranial aneurysms has its own risk of complications including intraoperative rupture and thromboembolic events.7
Circulation, Ahead of Print. BACKGROUND:Abdominal aortic aneurysm (AAA) is a potentially life-threatening vascular condition, but approved medical therapies to prevent AAA progression and rupture are currently lacking. Sphingolipid metabolism disorders are associated with the occurrence and development of AAA.
Circulation, Ahead of Print. Aortopathy encompasses a spectrum of conditions predisposing to dilation, aneurysm, dissection, or rupture of the aorta and other blood vessels.
Introduction:Intracranial aneurysm (IA), a cerebrovascular disease affecting 3-5% of US population, leads to subarachnoid hemorrage. This demonstrates the potential of using circulating blood to screen for IA presence. Stroke, Volume 56, Issue Suppl_1 , Page A78-A78, February 1, 2025.
The patient's heart had significant recovery: Echo : Estimated LVEF 32%, apical wall motion abnormality with diastolic distortion (LV aneurysm), suggestive of old MI. A followup ECG was recorded 2 days later: No definite evidence of infarction. It was uncertain whether this represented: 1.
Objective:To determine whether first pass effect (FPE) after mechanical thrombectomy (MT) for anterior circulation large vessel occlusion acute ischemic stroke (LVO-AIS) is modified by procedural time (PT).Methods:The
Methods:This was a retrospective observational study using data from the large multicenter international Stroke Thrombectomy and Aneurysm Registry (STAR). We aimed to investigate the impact of converting from one MT technique to another on the second MT attempt for AIS among patients with large vessel occlusion (LVO).Methods:This
Circulation: Cardiovascular Interventions, Ahead of Print. IVUS was associated with a lower risk of the primary outcome at 30-days (hazard ratio, 0.80 [95% CI, 0.730.89];P<0.001) and 6-months (hazard ratio, 0.93 [95% CI, 0.870.99];P=0.022) for all-comers.
After several patients in this series developed subarachnoid hemorrhage from a ruptured mycotic aneurysm, we proceeded to institute weekly cerebral angiography protocol. This detected moderate to severe vasospasm in 75%, and aneurysms in 58%, with the most common site being the basilar artery.
The aim of this study is to develop and validate a stroke prediction tool for outcome in MT for AIS patients with low ASPECTS using data from an ongoing international multicenter registry, the Stroke Thrombectomy and Aneurysm Registry (STAR).Methods:236
Circulation, Volume 150, Issue Suppl_1 , Page A4118882-A4118882, November 12, 2024. Introduction:Sinus of Valsalva aneurysm (SVA) accounts for 3.5% Aneurysm rupture typically forms a fistula into the right ventricle (60%), right atrium (29%), left atrium (6%), or left ventricle (4%), and rarely into the pericardial cavity (1%).
Interventional systems are also used to precisely plan and carry out complex neurovascular procedures such as the repair of brain aneurysms and birth defects. Circulation. PMID: 34756176; PMCID: PMC8727355. link] [3] Virani S.S., Benjamin E.J., 2020;141:e139–e596. doi: 10.1161/CIR.0000000000000757. 0000000000000757.
Circulation, Volume 150, Issue Suppl_1 , Page A4142012-A4142012, November 12, 2024. Coronary angiography revealed a tortuous and extremely aneurysmal RCA, as well as multivessel coronary artery disease (mvCAD) involving LAD, D1, LCx, OM1. Notably, the LAD had multiple aneurysmal segments and areas of eccentric stenosis upto 90%.Multislice
1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3 2019 Sep 10;140(11):e649-e650] [published correction appears in Circulation. 2020 Jan 28;141(4):e60] [published correction appears in Circulation.
Studies have reported dysregulation in extracellular matrix-related molecules and increased circulating inflammatory cytokines/chemokines in MMD patients, suggesting a role of immune responses in the development of MMD. Peripheral blood mononuclear cells (PBMCs) were isolated and cryopreserved.
Circulation, Volume 150, Issue Suppl_1 , Page A4144326-A4144326, November 12, 2024. The integrity of the ventricular wall decreased after the resection of large occupation, leading to reduced ventricular function or complications such as ventricular aneurysms.
Circulation, Volume 150, Issue Suppl_1 , Page A4143083-A4143083, November 12, 2024. More commonly, LDS presents with widespread arterial and aortic aneurysms that carry a high risk of dissection. Case Description:A 28-year-old G2P1 woman presented at 27 weeks gestation with progressive dyspnea and lower extremity edema.
Circulation, Volume 150, Issue Suppl_1 , Page A4145414-A4145414, November 12, 2024. Cervical adenopathy and hepatitis are more common in adults while coronary artery aneurysms are rarer. Incomplete KD is characterized by less than 4 of the classic clinical findings of mucocutaneous inflammation and is more common in adults.
Of the 32 patients, 9(28.1%) had dissection with diagnostic angiograms, 6(18.8%) endovascular thrombectomy, 15(46.9%) aneurysm treatment, and 2(6.3%) angioplasty with or without stenting. Common comorbidities included hypertension (62.5%), smoking (56.3%), and hyperlipidemia (46.9%).
In apolipoprotein E−/−and wild‐type mice, BAR502, a dual GPBAR1/FXR agonist, alone or in combination with atorvastatin, reduced cholesterol and low‐density lipoprotein plasma levels, mitigated the development of liver steatosis and aortic plaque formation, and shifted the polarization of circulating leukocytes toward an anti‐inflammatory phenotype.
Circulation, Volume 150, Issue Suppl_1 , Page A4140451-A4140451, November 12, 2024. Background:Stem cell antigen-1 (Sca-1) marks progenitor cells that contribute to vessel remodeling by differentiating into vascular smooth muscle cells and related myofibroblasts. Partial- or total loss of Sca-1 worsened aortic dilation [Sca1KI-/-1.25±0.06
Persistent ST elevation 3 days after a nearly transmural MI portends possible LV aneurysm. It is very unlikely to be LV aneurysm morphology when the ST elevation is so high and the T-Wave inversion is so deep. Circulation 1999;99(15):1972-7. Circulation 2000;101(2):125-30. Circulation 1998;97(23):2303-6.
Recurrent posterior circulation strokes in the setting of optimal medical management should clue clinicians to consider other etiologies of stroke. Contralateral vertebral artery stenosis, which is unable to supply retrograde flow during compression, is the likely etiology of this patient's strokes.
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