Journal of the American Heart Association

NOVEMBER 23, 2023

In apolipoprotein E−/−and wild‐type mice, BAR502, a dual GPBAR1/FXR agonist, alone or in combination with atorvastatin, reduced cholesterol and low‐density lipoprotein plasma levels, mitigated the development of liver steatosis and aortic plaque formation, and shifted the polarization of circulating leukocytes toward an anti‐inflammatory phenotype.

Aortic 40

Aortic Aneurysm Plaque Cholesterol 40

DAIC

JANUARY 23, 2024

1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3 2019 Sep 10;140(11):e649-e650] [published correction appears in Circulation. 2020 Jan 28;141(4):e60] [published correction appears in Circulation.

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

DAIC

OCTOBER 23, 2024

Vascular conditions can slow circulation and impact the way the body functions. Risk factors for vascular disease include having diabetes, use or history of tobacco products, high cholesterol, and/or high blood pressure. More than 8 in 10 (85%) people are not familiar with the role of vascular surgeons.

Peripheral Arterial Disease 40

Peripheral Arterial Disease Quality of Life Risk Factors Education 40