Journal of Cardiovascular Pharmacology

MARCH 18, 2025

Thoracic aortic aneurysm (TAA) is a life-threatening condition that currently lacks an effective therapeutic strategy. In the mouse TAA model, TMAO exacerbates aortic dilation and degeneration, promoting the development of thoracic aortic aneurysm. Furthermore, TMAO was observed to impair murine cardiac function.

Aneurysm 40

Aneurysm Aortic Cardiac Function Cardiovascular Disease 40

Dr. Smith's ECG Blog

JANUARY 27, 2024

Smith : Old inferior MI with persistent ST Elevation ("inferior aneurysm") has well-formed Q-waves. In inferior aneurysm, we usually see QR-waves, whereas for anterior aneurysm, we see QS-waves (no R- or r-wave at all!). The patient had a history of ‘NSTEMI’ a decade prior, with an RCA stent.

Chest Pain 117

Chest Pain STEMI Aneurysm Stents 117

American College of Cardiology

AUGUST 19, 2024

Does incorporating polygenic risk into a clinical model improve estimation of ascending aortic diameter and the ascertainment of aneurysm as well as thoracic aortic dissection beyond clinical factors alone?

Aortic 58

Aortic Aneurysm Article 58

American College of Cardiology

JULY 23, 2024

What are the aortic-related mortality (ARM) and the risk of aortic aneurysm (AA) rupture after fenestrated-branched endovascular aortic repair (FB-EVAR) for the treatment of thoracoabdominal aortic aneurysm (TAAA)?

Aneurysm 50

Aneurysm Aortic Article 50

Frontiers in Cardiovascular Medicine

JUNE 30, 2024

In this article, we first describe how ERK signaling contributes to preserving cardiovascular health. We then summarize current knowledge of the roles played by ERK in the development and progression of cardiac and vascular disorders, including atherosclerosis, myocardial infarction, cardiac hypertrophy, heart failure, and aortic aneurysm.

Cardiovascular Disease 52

Cardiovascular Disease Quality of Life Myocardial Infarction Aneurysm 52

American College of Cardiology

JUNE 11, 2024

In this interview, Hector I. Michelena, MD, FACC and W. Douglas Weaver MD, MACC discuss the history of and complications associated with bicuspid valvuloaortopathy.

Bicuspid/Mitral 45

Bicuspid/Mitral Aortic valve Aneurysm Aortic 45

American College of Cardiology

OCTOBER 15, 2024

What is the difference in incidence and repair of abdominal aortic aneurysms (AAAs) between countries with different screening practices?

Aneurysm 45

Aneurysm Aortic Article 45

American College of Cardiology

JULY 31, 2024

Eagle looks at a prospective multicenter cohort study that examined early and late aortic-related mortality and rupture after fenestrated-branched endovascular aortic repair of thoracoabdominal aortic aneurysms.

Aortic 45

Aortic Aneurysm Stenosis Article 45

Dr. Smith's ECG Blog

JANUARY 31, 2020

Although diagnostic of MI, it is highly suspicious for " Old inferior MI with persistent ST Elevation" or "inferior aneurysm morphology" because of the well-formed Q-waves and the flat T-waves. To repeat: in contrast, anterior aneurysm is much more easily distinguished from acute MI due to the QS-waves.

Angina 52

Angina Stents Stent Aneurysm 52

Stroke Journal

FEBRUARY 1, 2024

Review articles and meta-analyses were excluded. Optimization of LLM prompts may help with specificity, and weighting articles by type or perceived quality may improve accuracy. Here we use GPT3.5, Here we use GPT3.5, Using custom code via the GPT3.5 Results:Mean efficacy scores for N, M, and IH were 0.67, 0.32, and 0.15

Article 40

Article Hemorrhage Aneurysm Hypertension 40

Stroke Journal

JANUARY 30, 2025

Articles evaluating risk of acute ischemic stroke (AIS) and/or intracranial hemorrhage (ICH) in patients with IE were included. Meta-analysis was feasible for only some predictive factors due to study heterogeneity.

Risk Factors 40

Risk Factors Stroke Strokes Hemorrhage 40

Dr. Smith's ECG Blog

JANUARY 9, 2024

These are all findings that can be expected with left ventricular aneurysm. Many advances in treatment have occurred in the 28 years since this article was published. That said — misdiagnosis of WCT rhythms for the same reasons cited by the authors remains all-too-common — so the lessons put forth in this 1995 article remain relevant.

Tachycardia 119

Tachycardia Electrophysiology Atrial Flutter Ischemia 119

Dr. Smith's ECG Blog

OCTOBER 26, 2011

Persistent ST elevation 3 days after a nearly transmural MI portends possible LV aneurysm. It is very unlikely to be LV aneurysm morphology when the ST elevation is so high and the T-Wave inversion is so deep. Echo at this time showed some improvement in EF to 40%, but persistent akinesis and thrombus. Cath showed a 95% LAD with flow.

STEMI 52

STEMI Chest Pain Myocardial Infarction Angioplasty 52

Dr. Smith's ECG Blog

SEPTEMBER 27, 2019

Once dissecting aneurysm was ruled out by chest aorta CT — the possibility of acute ischemic heart disease becomes paramount. B ONUS — The 3 page article by Rowlands and Moore that I’ve posted in Figures-2 , 3 and 4 below is the BEST description I’ve seen of how to quickly determine which extremity is the source of the A rtifact ).

Chest Pain 52

Chest Pain Blog Ischemia Article 52

Dr. Smith's ECG Blog

MAY 19, 2020

The patient's heart had significant recovery: Echo : Estimated LVEF 32%, apical wall motion abnormality with diastolic distortion (LV aneurysm), suggestive of old MI. A followup ECG was recorded 2 days later: No definite evidence of infarction. It was uncertain whether this represented: 1. A list of conditions that can cause this is below.

Defibrillator 52

Defibrillator Circulation Plaque Cardiac Arrest 52

Dr. Smith's ECG Blog

DECEMBER 18, 2022

If you still have not read it, I strongly recommend that you read the following article on the diagnosis of "posterior" MI: Ischemic ST-Segment Depression Maximal in V1-V4 (Versus V5-V6) of Any Amplitude Is Specific for Occlusion Myocardial Infarction (Versus Nonocclusive Ischemia), by Meyers HP et al. His peak troponin was over 5000 ng/L.

Myocardial Infarction 40

Myocardial Infarction Chest Pain Blog Echocardiogram 40

Journal of Cardiovascular Pharmacology

APRIL 8, 2024

Aneurysms are localized dilations of blood vessels, which can expand to 50% of the original diameter. The pathophysiology of aneurysms is complex and diverse, often associated with progressive vessel wall dysfunction resulting from vascular smooth muscle cell (VSMC) death and abnormal extracellular matrix synthesis and degradation.

Aneurysm 40

Aneurysm Cerebrovascular Disease Biomarkers Article 40

American College of Cardiology

OCTOBER 2, 2024

In this week’s View, Dr. Eagle looks at sex-specific differences in alive hospital discharge following abdominal aortic aneurysm (AAA) repair.

Aortic 60

Aortic Hospital Aneurysm Stenosis 60

Dr. Paddy Barrett

JUNE 14, 2024

The cause of this arterial rupture was very likely an aneurysm that had grown over time and ruptured. These aneurysms are rare. It was a rare pancreatic aneurysm that nearly killed him at age 58 while sitting in a cabin with his wife in upstate New York. He survived. By the skin of his teeth. But Here’s The Thing.

Aneurysm 86

Aneurysm Quality of Life Heart Disease Diet 86

American College of Cardiology

SEPTEMBER 30, 2024

What are the sex-specific differences and drivers of the rate of alive hospital discharge following infrarenal abdominal aortic aneurysm (AAA) repair?

Hospital 53

Hospital Aneurysm Aortic Article 53

Dr. Smith's ECG Blog

APRIL 8, 2015

Look for Vascular Etiology -- think of these while doing H and P: --Bleeding: ruptured AAA, GI bleed, ruptured ectopic pregnancy, other spontaneous bleed such as mesenteric aneurysms. Annotated Bibliography For an excellent overview of ED Syncope management , see this article by Kessler C et al. starts at end of article on p.

Arrhythmia 52

Arrhythmia Outcomes Risk Factors Chest Pain 52

European Journal of Heart Failure

NOVEMBER 14, 2023

Significant LGE at CMR; LVEF <50%; abnormal blood pressure response during exercise test; LV apical aneurysm; high-risk genotype. *Syncope, LGE on CMR, inducible sustained VT at PES, pathogenic mutations in LMNA, PLN, FLNC, and RBM20.

Sudden Cardiac Death 40

Sudden Cardiac Death Cardiomyopathy Risk Factors Heart Failure 40