Remove Aneurysm Remove Aortic Remove Pulmonary
article thumbnail

Endothelial SMAD4 Deficiency Promotes Pulmonary Hypertension by Impairing Cell Adhesion and Extracellular Matrix Organization

Hypertension Journal

BACKGROUND:Aberrant BMPR2 (bone morphogenetic protein receptor 2) signaling is associated with the pathogenesis of pulmonary hypertension. By contrast, mice with smooth muscle cell-specificSmad4deletion had no pulmonary hypertension but rather displayed evident aortic aneurysm and dissection.

article thumbnail

Ascending aorta dilatation for pulmonary atresia with ventricular septal defect: a report of three adult cases

Journal of Cardiothoracic Surgery

Patients with pulmonary atresia and ventricular septal defect (PA/VSD) are prone to progressive aortic dilation. However, there are relatively few reports of progressive development of aortic aneurysm or aorti.

VSD 52
article thumbnail

Dyspnoea in a young woman

Heart BMJ

Pulmonary agenesis D. Ascending aortic aneurysm Answer: As the patient is a known case of arterial tortuosity syndrome, which is a rare hereditary disorder characterised by lengthening, dilatation and tortuosity of large and medium-sized arteries. The other images of the aneurysm are shown in. Left lung collapse C.

article thumbnail

X-Ray Chest PA View in Severe PAH

All About Cardiovascular System and Disorders

The striking finding is the huge enlargement of the right pulmonary artery, almost aneurysmal dilatation of right pulmonary artery. Main pulmonary artery is also grossly dilated. And you can see left pulmonary artery shadow and rest of it is not seen here. This is the aortic knuckle.

VSD 52
article thumbnail

Systematic review of cardiovascular neurocristopathy—contemporary insights and future perspectives

Frontiers in Cardiovascular Medicine

Cardiovascular neurocristopathy, i.e., cardiopathy and vasculopathy, associated with the NCC could occur in the form of (1) cardiac septation disorders, mainly the aortico-pulmonary septum; (2) great vessels and vascular disorders; (3) myocardial dysfunction; and (4) a combination of all three phenotypes.

article thumbnail

2023 STS Coding Workshop

Society of Thoracic Surgeons - Allied Health

hours total) Joseph Turek, MD, Jeffrey P. hours total) Richard Freeman, MD and John A.

article thumbnail

Mineralocorticoid Receptors in Vascular Smooth Muscle: Blood Pressure and Beyond

Hypertension Journal

By these mechanisms, SMC-MR promotes disease progression in models of aging-associated vascular stiffness, vascular calcification, mitral and aortic valve disease, pulmonary hypertension, and heart failure. While rarely tested, when sexes were compared, the mechanisms of SMC-MR-mediated disease were sexually dimorphic.