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An aorticaneurysm is a very serious condition that occurs when the aorta (the largest artery in the body that comes off the heart) develops a bulb-like formation. Factors such as high blood pressure and high cholesterol can… Source Factors such as high blood pressure and high cholesterol can… Source
Mice lackingFxrandGpbar1−/−/Fxr−/−display hypotension and aortic inflammation, along with altered intestinal permeability that deteriorates with age, and severe dysbiosis, along with dysregulated bile acid synthesis. Vasomotor activities of aortic rings were altered byGpbar1andFxrgene ablation.
Blood lipids such as cholesterol and triglycerides are causal risk factors for coronary heart disease as well as several other types of cardiovascular disease , such as aortic stenosis). Smoking is a prevalent risk factor among people who have an abdominal aorticaneurysm.
Risk factors for vascular disease include having diabetes, use or history of tobacco products, high cholesterol, and/or high blood pressure. Key Survey Highlights ● Nearly 1 in 3 (29%) Americans have not heard of any of the most common vascular diseases, like peripheral artery disease, carotid artery disease, or abdominal aorticaneurysm.
1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aorticaneurysm).3 Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2
ObjectiveRobust evidence has demonstrated that inflammation plays an important role in the occurrence and development of abdominal aorticaneurysms (AAA). However, whether UHR is associated with AAA remains unclear.
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