Remove Aneurysm Remove Aortic Remove Biomarkers
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Single-cell RNA sequencing and ATAC sequencing identify novel biomarkers for bicuspid aortic valve-associated thoracic aortic aneurysm

Frontiers in Cardiovascular Medicine

IntroductionBicuspid aortic valve (BAV) is the most prevalent congenital cardiovascular defect and known to cause thoracic aortic aneurysms (TAAs).

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Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G?Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease

Journal of the American Heart Association

The expression of GPBAR1 in the human endothelium correlated with the expression of inflammatory biomarkers. The expression of GPBAR1 in the human endothelium correlated with the expression of inflammatory biomarkers. Vasomotor activities of aortic rings were altered byGpbar1andFxrgene ablation.

Aortic 40
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Lowering Atherosclerotic Cardiovascular Disease Events by Treating Residual Inflammatory Risk

DAIC

1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3 Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2

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A Proteomics-Based Approach for Prediction of Different Cardiovascular Diseases and Dementia

Circulation

BACKGROUND:Many studies have explored whether individual plasma protein biomarkers improve cardiovascular disease risk prediction. CONCLUSIONS:Measurement of targeted protein biomarkers produced superior prediction of aggregated and disaggregated cardiovascular events. Circulation, Ahead of Print.

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Feature genes identification and immune infiltration assessment in abdominal aortic aneurysm using WGCNA and machine learning algorithms

Frontiers in Cardiovascular Medicine

ObjectiveAbdominal aortic aneurysm (AAA) is a life-threatening vascular condition. These genes are linked to immune cell activity and the inflammatory microenvironment, providing potential biomarkers for early detection and a basis for further research into AAA progression.

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The serum uric acid/high-density lipoprotein cholesterol ratio: a novel predictor for the presence of abdominal aortic aneurysm

Frontiers in Cardiovascular Medicine

ObjectiveRobust evidence has demonstrated that inflammation plays an important role in the occurrence and development of abdominal aortic aneurysms (AAA). However, whether UHR is associated with AAA remains unclear.

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Chest pain followed by 6 days of increasing dyspnea -- what happened?

Dr. Smith's ECG Blog

When there are QS-waves, one should always think about LV aneurysm, but ST to QRS ratio and T-wave to QRS ratio are far too large and not compatible with left ventricular aneurysm. Larger shunt volume means less blood exiting the left ventricle through the aortic valve and lower cardiac output. This ECG shows a lot of "acuity".