Aneurysm and Aortic - Cardiovascular Update

Obstructive sleep apnea may increase risk of abdominal aortic aneurysms

Medical Xpress - Cardiology

SEPTEMBER 25, 2024

Obstructive sleep apnea may be a risk factor for developing abdominal aortic aneurysms, according to researchers from the University of Missouri School of Medicine and NextGen Precision Health.

Aneurysm

Aneurysm Aortic Physiology Risk Factors

Contribution of rare chromosome 22q11.2 copy number variants to non-syndromic bicuspid aortic valve

Heart BMJ

FEBRUARY 12, 2025

Background Bicuspid aortic valve (BAV) is the most common congenital heart defect in adults, often leading to complications such as thoracic aortic aneurysms and aortic stenosis. While BAV is frequently associated with 22q11.2 This study is aimed to assess the role of rare 22q11.2 region (18–24 Mb).

Aortic valve

Aortic valve Bicuspid/Mitral Aortic Aneurysm

Coarctation of Aorta and Ascending Aortic Aneurysm

American College of Cardiology

MARCH 22, 2024

What is the relationship between coarctation of the aorta (COA), bicuspid aortic valve (BAV), and thoracic aortic aneurysms?

Aneurysm

Aneurysm Aortic Aortic valve Bicuspid/Mitral

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

MORE WEBINARS

Smidt Heart Institute Opens Aortic Surveillance Clinic

DAIC

DECEMBER 20, 2023

Experts at the Smidt Heart Institute's new Aortic Surveillance Clinic will monitor patients with aortic aneurysms (illustrated here) or enlarged aortas. Smidt Heart Institute patients benefit from access to a multidisciplinary team including cardiac and vascular surgeons skilled in treating a range of aortic conditions. “We

Aortic

Aortic Aneurysm Aortic valve Nursing

Advances and challenges in regenerative therapies for abdominal aortic aneurysm

Frontiers in Cardiovascular Medicine

JUNE 3, 2024

Abdominal aortic aneurysm (AAA) is a significant source of mortality worldwide and carries a mortality of greater than 80% after rupture. Despite extensive efforts to develop pharmacological treatments, there is currently no effective agent to prevent aneurysm growth and rupture.

Aneurysm

Aneurysm Aortic Pharmacology Innovation

Diabetes does not increase in-hospital or short-term mortality in patients undergoing surgical repair for type A aortic dissection: insight from the national readmission database

Cardiovascular Diabetology

DECEMBER 5, 2024

Previous studies have reported a protective effect of type 2 diabetes on the incidence and progression of aortic aneurysms. We investigated whether this protective effect extends to aortic dissections.

Aortic

Aortic Diabetes Aneurysm Hospital

Intermountain 1st in US to perform aortic aneurysm procedure

Becker's Hospital Review - Cardiology

OCTOBER 21, 2024

to use the Gore EXCLUDER Thoracoabdominal Branch Endoprosthesis device for the treatment of an aortic aneurysm outside of a clinical trial. A vascular surgeon at Salt Lake City-based Intermountain Health has become the first in the U.S.

Aneurysm

Aneurysm Aortic

The link between high blood pressure and aortic aneurysms

CTVS

SEPTEMBER 26, 2024

An aortic aneurysm is a very serious condition that occurs when the aorta (the largest artery in the body that comes off the heart) develops a bulb-like formation. Factors such as high blood pressure and high cholesterol can… Source

Blood Pressure

Blood Pressure Aneurysm Aortic Cholesterol

Causal relationship between mitochondrial proteins and risks of aortic aneurysms and aortic dissection: a Mendelian randomization study

Journal of Cardiothoracic Surgery

APRIL 4, 2025

Mitochondrial dysfunction may be linked to the development of aortic aneurysm (AA) and aortic dissection (AD). This study aimed to evaluate the potential associations between proteins related to mitochondrial.

Aneurysm

Aneurysm Aortic Research

A bibliometric analysis of abdominal aortic aneurysm (2014–2024)

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2024

BackgroundAbdominal aortic aneurysm (AAA) is a localized bulge of the abdominal aorta, which mainly manifests as a pulsatile mass in the abdomen. Once an abdominal aortic aneurysm ruptures, the patient's life is seriously endangered. Surgery is the preferred treatment for abdominal aortic aneurysm.

Aneurysm

Aneurysm Aortic Research Download

Application of three-dimensional printing in the planning and execution of aortic aneurysm repair

Frontiers in Cardiovascular Medicine

JANUARY 28, 2025

IntroductionThe accuracy of fenestrations in stent grafts for complex aortic aneurysms and dissections can be significantly improved using three-dimensional (3D)-printed phantoms. Standardization is enhanced by using artificial intelligence (AI) for image pre-processing before 3D printing.

Aneurysm

Aneurysm Aortic Stents Stent

Study on the clinical value of computed tomography angiography in the diagnosis of aortic aneurysm

Journal of Cardiothoracic Surgery

AUGUST 27, 2024

Background The aim of this study is to explore the clinical value of computed tomography angiography (CTA) in the diagnosis of aortic aneurysm. Results There was no significant difference in the accuracy of diagnosing aortic aneurysms (P > 0.05) between DSA [98.33% (59/60)] and CTA [95.00% (57/60)].

Aneurysm

Aneurysm Aortic Hospital Research

Postoperative serum mir-28-5p level has predictive value for the prognosis after endovascular abdominal aortic aneurysm repair

Journal of Cardiothoracic Surgery

APRIL 24, 2024

We explored the clinical significance of miR-28-5p pre- and post-endovascular abdominal aortic aneurysm repair (EVAR) in abdominal aortic aneurysm (AAA) patients.

Aneurysm

Aneurysm Aortic Research

Deep learning techniques for imaging diagnosis and treatment of aortic aneurysm

Frontiers in Cardiovascular Medicine

FEBRUARY 27, 2024

Objective This study aims to review the application of deep learning techniques in the imaging diagnosis and treatment of aortic aneurysm (AA), focusing on screening, diagnosis, lesion segmentation, surgical assistance, and prognosis prediction.

Aneurysm

Aneurysm Aortic Stents Stent

Modern management of ruptured abdominal aortic aneurysm

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2023

Ruptured abdominal aortic aneurysms (rAAA) remain one of the most clinically challenging and technically complex emergencies in contemporary vascular surgery practice.

Aneurysm

Aneurysm Aortic Physiology Outcomes

Successful chimney endovascular aortic repair with reconstruction of three visceral branches for huge saccular juxtarenal abdominal aortic aneurysm after trans-thoracoabdominal esophagectomy

Journal of Cardiothoracic Surgery

MAY 3, 2024

Conventional graft replacement for a juxtarenal abdominal aortic aneurysm (JRAAA) remains challenging for high-risk patients since it often requires the reconstruction of some visceral arteries.

Aneurysm

Aneurysm Aortic

Case Report: Combined transcatheter arterial embolization and aortic stent-graft have better efficacy for bronchial artery aneurysms

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Bronchial artery aneurysm (BAA) is a rare and fatal condition that requires immediate treatment. In the present case, a 76-year-old hypertensive woman was admitted with dizziness and diagnosed with an unruptured bronchial artery aneurysm, which was treated by transcatheter arterial embolization and aortic stent-graft.

Embolism

Embolism Aneurysm Stents Stent

Homemade pericardial bifurcated graft for Q fever-infected abdominal aortic aneurysm open repair: a case report

Frontiers in Cardiovascular Medicine

MAY 27, 2024

In rare cases, it can lead to vascular complications, including infected aneurysms. We report a case of abdominal aortic aneurysm infected by C. Successful treatment involves surgery and antibiotics, but there is no established consensus or clear recommendation for the choice of material graft.

Aneurysm

Aneurysm Aortic

Placement of stent grafts with different calibers into the true and false lumens of anastomotic aneurysms after descending aortic replacement for aortic dissection

Journal of Cardiothoracic Surgery

JANUARY 5, 2024

Anastomotic aneurysms present as a life-threatening emergency after descending aortic replacement for aortic dissection. Thoracic endovascular aneurysm repair (TEVAR) has been performed since the early 2000s f.

Aneurysm

Aneurysm Aortic Stents Stent

Lipid metabolism-associated metabolites on cardiovascular diseases: a two-sample Mendelian randomized study

Frontiers in Cardiovascular Medicine

MARCH 28, 2025

All statistical analyses were rigorously executed in R software.ResultsOur findings identified causal relationships between 15 metabolites and cardiovascular disease.

Cardiovascular Disease

Cardiovascular Disease Atrial Fibrillation Aneurysm Heart Failure

Endovascular management of a spontaneous aorto-caval fistula resulting from abdominal aortic aneurysm: case report and literature review

Frontiers in Cardiovascular Medicine

JANUARY 29, 2025

BackgroundAorto-caval fistula is a rare complication of abdominal aortic aneurysms that can occur spontaneously, iatrogenically, or traumatically, associated with high morbidity and mortality. Computed tomography angiography revealed an aorto-caval fistula complicating infrarenal abdominal aortic aneurysm.

Aneurysm

Aneurysm Aortic Stents Stent

Epigenetic modifications in abdominal aortic aneurysms: from basic to clinical

Frontiers in Cardiovascular Medicine

JUNE 3, 2024

Abdominal Aortic Aneurysm (AAA) is a disease characterized by localized dilation of the abdominal aorta, involving multiple factors in its occurrence and development, ultimately leading to vessel rupture and severe bleeding. AAA has a high mortality rate, and there is a lack of targeted therapeutic drugs.

Aneurysm

Aneurysm Aortic

Latin Heart Rounds Series: Rounds on a Patient with Ascending Aortic Aneurysm and Arch Involvement

Society of Thoracic Surgeons - Congenital

OCTOBER 11, 2023

Webinar Latin Heart Rounds Series: Rounds on a Patient with Ascending Aortic Aneurysm and Arch Involvement dkaczmarek Wed, 10/11/2023 - 11:22 December 15, 2023 Image Join us on December 15, when experts will provide up-to-date insight on the management of patients with aortic root and ascending aortic aneurysm involving the aortic arch.

Aneurysm

Aneurysm Aortic Webinar Aortic valve

AORTA Gene Score for Ascending Aortic Dilation

American College of Cardiology

AUGUST 19, 2024

Does incorporating polygenic risk into a clinical model improve estimation of ascending aortic diameter and the ascertainment of aneurysm as well as thoracic aortic dissection beyond clinical factors alone?

Aortic

Aortic Aneurysm Article

Researchers investigate why aortic aneurysms form at the arch or in the abdominal segment

Medical Xpress - Cardiology

JULY 5, 2024

These so-called aortic aneurysms typically form in the same sites of the large blood vessel: either on the upper arch or in the abdominal cavity. A vascular dilatation in the aorta can be life-threatening if it bursts.

Aneurysm

Aneurysm Aortic Research

S-Nitrosylation of Septin2 Exacerbates Aortic Aneurysm and Dissection by Coupling the TIAM1-RAC1 Axis in Macrophages

Circulation

FEBRUARY 15, 2024

Aortic aneurysm and dissection are high-risk cardiovascular diseases without an effective cure. Angiotensin II–induced aortic aneurysm model and β-aminopropionitrile–induced aortic aneurysm and dissection model were used to determine the role of SNO of Septin2 (SNO-Septin2) in aortic aneurysm and dissection development.

Aneurysm

Aneurysm Aortic Cardiovascular Disease Pharmacology

Single-cell RNA sequencing and ATAC sequencing identify novel biomarkers for bicuspid aortic valve-associated thoracic aortic aneurysm

Frontiers in Cardiovascular Medicine

APRIL 8, 2024

IntroductionBicuspid aortic valve (BAV) is the most prevalent congenital cardiovascular defect and known to cause thoracic aortic aneurysms (TAAs).

Aortic valve

Aortic valve Aortic Aneurysm Biomarkers

Predictive value of geriatric nutritional risk index in cardiac and cerebrovascular events after endovascular aortic aneurysm repair

Frontiers in Cardiovascular Medicine

OCTOBER 7, 2024

ObjectiveTo evaluate the effect of malnutrition assessed by the Geriatric Nutritional Risk Index (GNRI) on major adverse cardiac and cerebrovascular events (MACCE) in the elderly patients after endovascular aortic aneurysm repair (EVAR).Materials Malnutrition status was assessed by the GNRI.

Aneurysm

Aneurysm Aortic Hospital Outcomes

Can this thumb test tell if you are at increased risk of a hidden aortic aneurysm?

Medical Xpress - Cardiology

MAY 5, 2024

All the parts of our bodies share an inherent connectivity. This goes much further than "the foot bone's connected to the … leg bone." For instance, both hands and feet are connected to a constantly flowing bloodstream, and a nerve network that makes their muscles kick.

Aneurysm

Aneurysm Aortic

Protein Drug Targets for Abdominal Aortic Aneurysm and Proteomic Associations Between Modifiable Risk Factors and Abdominal Aortic Aneurysm

Journal of the American Heart Association

FEBRUARY 26, 2025

BackgroundAbdominal aortic aneurysm (AAA) is a severe aortic disease for which no pharmacological interventions have yet been developed. Journal of the American Heart Association, Ahead of Print.

Aneurysm

Aneurysm Risk Factors Aortic Obesity

Thoracoabdominal aortic replacement in a 6-year-old boy with Loeys-Dietz syndrome

Journal of Cardiothoracic Surgery

SEPTEMBER 17, 2024

Connective tissue disorders such as Marfan- and Loeys-Dietz syndrome (LDS) can lead to aortic aneurysms and aortic dissections in children. Patients with LDS often necessitating multiple aortic surgeries throu.

Aortic

Aortic Aneurysm

Aneurysm and subacute type a aortic dissection, in a pediatric patient with aortopathy

Journal of Cardiothoracic Surgery

FEBRUARY 19, 2025

Aortic dissection in pediatrics is an extremely rare condition, which is generally related to predisposing factors such as connective tissue disorders, congenital heart disease and systemic arterial hypertensi.

Pediatrics

Pediatrics Congenital Heart Disease Aortic Aneurysm

Proteome‐Wide Mendelian Randomization Identifies Therapeutic Targets for Abdominal Aortic Aneurysm

Journal of the American Heart Association

FEBRUARY 3, 2025

We conducted a comprehensive Mendelian randomization analysis across the proteome to identify potential protein markers and therapeutic targets for abdominal aortic aneurysm (AAA).Methods These proteincoding genes are primarily expressed in macrophages, smooth muscle cells, and mast cells within abdominal aortic aneurysm tissue.

Aneurysm

Aneurysm Aortic Cardiovascular Disease Diabetes

Trimethylamine N-oxide Aggravates Thoracic Aortic Aneurysm by Inhibiting Axl to Promote Vascular Smooth Muscle Cell Dysfunction

Journal of Cardiovascular Pharmacology

MARCH 18, 2025

Thoracic aortic aneurysm (TAA) is a life-threatening condition that currently lacks an effective therapeutic strategy. In the mouse TAA model, TMAO exacerbates aortic dilation and degeneration, promoting the development of thoracic aortic aneurysm. Furthermore, TMAO was observed to impair murine cardiac function.

Aneurysm

Aneurysm Aortic Cardiac Function Cardiovascular Disease

Successful open surgical treatment for persistent type II endoleak following thoracic endovascular aortic repair: a case report

Journal of Cardiothoracic Surgery

JULY 2, 2024

The occurrence of type II endoleaks after endovascular repair of aortic aneurysm has gradually gained increasing attention. We present a case of a patient with an expanding aneurysm after thoracic endovascular.

Aortic

Aortic Aneurysm

High proportion of undiagnosed diabetes in patients surgically treated for infrarenal abdominal aortic aneurysm: findings from the multicentre Norwegian Aortic Aneurysm and Diabetes (ABANDIA) Study

Cardiovascular Diabetology

SEPTEMBER 8, 2024

The aim was to investigate the total prevalence of known and undiagnosed diabetes mellitus (DM), and the association of DM with perioperative complications following elective, infrarenal, open surgical (OSR) o.

Diabetes

Diabetes Aneurysm Aortic Research

Fenestrated-Branched Endovascular Aortic Repair, Mortality and PCI, Lp(a) and Calcific Aortic Stenosis Progression

American College of Cardiology

JULY 31, 2024

In this weekâ€™s View, Dr. Eagle looks at a prospective multicenter cohort study that examined early and late aortic-related mortality and rupture after fenestrated-branched endovascular aortic repair of thoracoabdominal aortic aneurysms.

Aortic

Aortic Aneurysm Stenosis Article

Aortic pressures within a giant right coronary artery aneurysm

Journal of Cardiothoracic Surgery

DECEMBER 19, 2024

Giant coronary artery aneurysms are rare conditions with potentially devastating consequences. We report a case of the largest documented giant right coronary artery (RCA) aneurysm to date.

Aneurysm

Aneurysm Aortic Document

PP2A Attenuates Thoracic Aneurysm and Dissection in Mouse Models of Marfan Syndrome

Hypertension Journal

JANUARY 29, 2025

BACKGROUND:Recent studies show that hyperactivation of mTOR (mammalian target of rapamycin) signaling plays a causal role in the development of thoracic aortic aneurysm and dissection. Echocardiography was performed to monitor the growth of the aortic root and ascending aorta. Hypertension, Ahead of Print.

Aneurysm

Aneurysm Aortic Hypertension

Use of ultra-low contrast dose CT aortography for the management of aortic aneurysmal disease

Journal of Cardiothoracic Surgery

OCTOBER 2, 2024

Computed tomography aortography (CTA) is used in the assessment of aortic pathologies and planning of surgical intervention. However, its dependence on iodinated contrast can result in development of contrast-.

Aortic

Aortic Aneurysm Research

Autonomous Epinephrine Release by KCNJ5 Mutation Drives Familial Thoracic Aortic Aneurysm and Dissection

Hypertension Journal

FEBRUARY 5, 2025

BACKGROUND:The pathophysiology of familial thoracic aortic aneurysm and dissection (TAAD) is linked to genetic variants that affect aortic components. Hypertension, Ahead of Print. These findings establish a genetic link between systolic hypertension and TAAD.

Aneurysm

Aneurysm Aortic Hypertension Risk Factors

Endothelial SMAD4 Deficiency Promotes Pulmonary Hypertension by Impairing Cell Adhesion and Extracellular Matrix Organization

Hypertension Journal

APRIL 11, 2025

By contrast, mice with smooth muscle cell-specificSmad4deletion had no pulmonary hypertension but rather displayed evident aortic aneurysm and dissection.

Pulmonary

Pulmonary Hypertension Aneurysm Aortic

Extensive aortic replacement including aortic arch for a mega aorta with chronic aortic dissection via posterolateral thoracotomy

Journal of Cardiothoracic Surgery

SEPTEMBER 8, 2024

Mega-aortic syndrome including aortic arch and descending aortic aneurysm is a challenging surgical case. Because the aorta continuously dilates, creating the distal anastomosis sites becomes an issue. Despite.

Aortic

Aortic Aneurysm

Risk factors of 30-day and long-term mortality and outcomes in open repair of thoracoabdominal aortic aneurysm

Journal of Cardiothoracic Surgery

APRIL 1, 2024

Open repair of thoracoabdominal aortic aneurysm (TAAA) was characterized by significant risk of postoperative mortality and morbidity. The aim of this study was to determine the perioperative predictors of ear.

Aneurysm

Aneurysm Aortic Risk Factors Outcomes

Obstructive sleep apnea may increase risk of abdominal aortic aneurysms

Contribution of rare chromosome 22q11.2 copy number variants to non-syndromic bicuspid aortic valve

Coarctation of Aorta and Ascending Aortic Aneurysm

Webinars

Smidt Heart Institute Opens Aortic Surveillance Clinic

Advances and challenges in regenerative therapies for abdominal aortic aneurysm

Diabetes does not increase in-hospital or short-term mortality in patients undergoing surgical repair for type A aortic dissection: insight from the national readmission database

Intermountain 1st in US to perform aortic aneurysm procedure

The link between high blood pressure and aortic aneurysms

Causal relationship between mitochondrial proteins and risks of aortic aneurysms and aortic dissection: a Mendelian randomization study

A bibliometric analysis of abdominal aortic aneurysm (2014–2024)

Application of three-dimensional printing in the planning and execution of aortic aneurysm repair

Study on the clinical value of computed tomography angiography in the diagnosis of aortic aneurysm

Postoperative serum mir-28-5p level has predictive value for the prognosis after endovascular abdominal aortic aneurysm repair

Deep learning techniques for imaging diagnosis and treatment of aortic aneurysm

Modern management of ruptured abdominal aortic aneurysm

Successful chimney endovascular aortic repair with reconstruction of three visceral branches for huge saccular juxtarenal abdominal aortic aneurysm after trans-thoracoabdominal esophagectomy

Case Report: Combined transcatheter arterial embolization and aortic stent-graft have better efficacy for bronchial artery aneurysms

Homemade pericardial bifurcated graft for Q fever-infected abdominal aortic aneurysm open repair: a case report

Placement of stent grafts with different calibers into the true and false lumens of anastomotic aneurysms after descending aortic replacement for aortic dissection

Lipid metabolism-associated metabolites on cardiovascular diseases: a two-sample Mendelian randomized study

Endovascular management of a spontaneous aorto-caval fistula resulting from abdominal aortic aneurysm: case report and literature review

Epigenetic modifications in abdominal aortic aneurysms: from basic to clinical

Latin Heart Rounds Series: Rounds on a Patient with Ascending Aortic Aneurysm and Arch Involvement

AORTA Gene Score for Ascending Aortic Dilation

Researchers investigate why aortic aneurysms form at the arch or in the abdominal segment

S-Nitrosylation of Septin2 Exacerbates Aortic Aneurysm and Dissection by Coupling the TIAM1-RAC1 Axis in Macrophages

Single-cell RNA sequencing and ATAC sequencing identify novel biomarkers for bicuspid aortic valve-associated thoracic aortic aneurysm

Predictive value of geriatric nutritional risk index in cardiac and cerebrovascular events after endovascular aortic aneurysm repair

Can this thumb test tell if you are at increased risk of a hidden aortic aneurysm?

Protein Drug Targets for Abdominal Aortic Aneurysm and Proteomic Associations Between Modifiable Risk Factors and Abdominal Aortic Aneurysm

Thoracoabdominal aortic replacement in a 6-year-old boy with Loeys-Dietz syndrome

Aneurysm and subacute type a aortic dissection, in a pediatric patient with aortopathy

Proteome‐Wide Mendelian Randomization Identifies Therapeutic Targets for Abdominal Aortic Aneurysm

Trimethylamine N-oxide Aggravates Thoracic Aortic Aneurysm by Inhibiting Axl to Promote Vascular Smooth Muscle Cell Dysfunction

Successful open surgical treatment for persistent type II endoleak following thoracic endovascular aortic repair: a case report

High proportion of undiagnosed diabetes in patients surgically treated for infrarenal abdominal aortic aneurysm: findings from the multicentre Norwegian Aortic Aneurysm and Diabetes (ABANDIA) Study

Fenestrated-Branched Endovascular Aortic Repair, Mortality and PCI, Lp(a) and Calcific Aortic Stenosis Progression

Aortic pressures within a giant right coronary artery aneurysm

PP2A Attenuates Thoracic Aneurysm and Dissection in Mouse Models of Marfan Syndrome

Use of ultra-low contrast dose CT aortography for the management of aortic aneurysmal disease

Autonomous Epinephrine Release by KCNJ5 Mutation Drives Familial Thoracic Aortic Aneurysm and Dissection

Endothelial SMAD4 Deficiency Promotes Pulmonary Hypertension by Impairing Cell Adhesion and Extracellular Matrix Organization

Extensive aortic replacement including aortic arch for a mega aorta with chronic aortic dissection via posterolateral thoracotomy

Risk factors of 30-day and long-term mortality and outcomes in open repair of thoracoabdominal aortic aneurysm

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