article thumbnail

Unstable 'fluttering' predicts aortic aneurysm with 98% accuracy

Medical Xpress - Cardiology

Northwestern University researchers have developed the first physics-based metric to predict whether or not a person might someday suffer an aortic aneurysm, a deadly condition that often causes no symptoms until it ruptures.

Aneurysm 109
article thumbnail

Obstructive sleep apnea may increase risk of abdominal aortic aneurysms

Medical Xpress - Cardiology

Obstructive sleep apnea may be a risk factor for developing abdominal aortic aneurysms, according to researchers from the University of Missouri School of Medicine and NextGen Precision Health.

article thumbnail

Androgen aggravates aortic aneurysms via suppression of PD-1 in mice

Journal of Clinical Investigation - Cardiology

Androgen has long been recognized for its pivotal role in the sexual dimorphism of cardiovascular diseases, including aortic aneurysms (AAs), a devastating vascular disease with a higher prevalence and fatality rate in men than in women. However, the mechanism by which androgen mediates AAs is largely unknown.

Aneurysm 102
article thumbnail

Contribution of rare chromosome 22q11.2 copy number variants to non-syndromic bicuspid aortic valve

Heart BMJ

Background Bicuspid aortic valve (BAV) is the most common congenital heart defect in adults, often leading to complications such as thoracic aortic aneurysms and aortic stenosis. While BAV is frequently associated with 22q11.2 This study is aimed to assess the role of rare 22q11.2 region (18–24 Mb).

article thumbnail

Coarctation of Aorta and Ascending Aortic Aneurysm

American College of Cardiology

What is the relationship between coarctation of the aorta (COA), bicuspid aortic valve (BAV), and thoracic aortic aneurysms?

article thumbnail

Smidt Heart Institute Opens Aortic Surveillance Clinic

DAIC

Experts at the Smidt Heart Institute's new Aortic Surveillance Clinic will monitor patients with aortic aneurysms (illustrated here) or enlarged aortas. Smidt Heart Institute patients benefit from access to a multidisciplinary team including cardiac and vascular surgeons skilled in treating a range of aortic conditions. “We

Aortic 105
article thumbnail

Advances and challenges in regenerative therapies for abdominal aortic aneurysm

Frontiers in Cardiovascular Medicine

Abdominal aortic aneurysm (AAA) is a significant source of mortality worldwide and carries a mortality of greater than 80% after rupture. Despite extensive efforts to develop pharmacological treatments, there is currently no effective agent to prevent aneurysm growth and rupture.