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Hypertrophic Cardiomyopathy

All About Cardiovascular System and Disorders

Genetic markers for several of these disorders are also available commercially. SAM causes LVOTO, increased ejection time and a decreased stroke volume, as well as mitral regurgitation due to poor coaptation of the leaflets. Sigmoidal HCM which is about 40-50% has about 10% positivity for myofilament gene.