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Impacting 25 million people globally [1], deep venous disease results from venous thromboembolism, a condition that occurs when a bloodclot forms in the vein [2]. Deep venous anatomy and obstructions can present a multitude of complexities and mechanical challenges. It is the third most common cardiovascular disease [2].
Patients had a valve annulus of 430 mm2 or less and anatomy suitable for either the Evolut PRO/PRO+/FX or the SAPIEN 3/3 Ultra. Clinically, at one year, either valve is reasonable, and the results are pretty similar, although mild valve leaks and some measures of quality of life were better with Evolut.
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