CardiacWire

FEBRUARY 12, 2025

Bayer terminated its OCEANIC-AF trial for its Factor XI inhibitor, asundexian, due to 3x greater stroke (1.3% vs. 0.4%) and 4x higher ischemic stroke rates (csHR = 4.06). Results from BMS AXIOMATIC-SSP study found that its Factor XI inhibitor, milvexian, failed to meaningfully reduce ischemic stroke.

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AFIB Embolism Plaque Strokes 102

CardiacWire

JANUARY 24, 2025

Fully published results from Athos Therapeutics AZALEA-TIMI 71 trial for its novel Factor XI inhibitor abelacimab, confirming the drugs lower bleeding risks, but leaving researchers uncertain about its ability to prevent stroke in AFib patients. vs. 0.4%) and 4X ischemic stroke rates (csHR = 4.06). year follow-up.

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Strokes Stroke AFIB Thrombosis 59

CardiacWire

MARCH 19, 2025

LAAO (left atrial appendage occlusion) devices help prevent stroke in patients with AFib by sealing off the left atrial appendage where blood clots can form. Devices like the Amulet and Watchman provide an alternative to anticoagulants for AFib stroke prevention in patients who cannot take blood thinners.

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AFIB Blood Clot Embolism Strokes 52

DAIC

JANUARY 24, 2025

Affecting 60 million people worldwide 1 , the prevalence of atrial fibrillation (AFib) is expected to increase by 60% by 2050 due to an aging population and rising cardiometabolic risk factors 2. In addition, the Centers for Disease Control and Prevention (CDC) estimates that more than 12 million Americans will have AFib by 2030 3.

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AFIB Atrial Fibrillation General Cardiology Strokes 52

American College of Cardiology

NOVEMBER 17, 2024

Edoxaban was comparable to warfarin in preventing stroke or systemic embolism and intracardiac thrombus in patients with non-valvular atrial fibrillation (AFib) within three months after bioprosthetic valve surgery, based on preliminary findings from the ENBALV trial presented at AHA 2024.

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AFIB Atrial Fibrillation Embolism Strokes 51

American College of Cardiology

SEPTEMBER 1, 2024

Asundexian was associated with a higher incidence of stroke or systemic embolism, but less major bleeding, compared with apixaban among patients with atrial fibrillation (AFib) who were at high risk for stroke, based on findings from the OCEANIC-AF trial presented at ESC Congress 2024 in London and simultaneously published in The New England Journal (..)

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AFIB Atrial Fibrillation Embolism Research 42

EMS 12-Lead

AUGUST 25, 2024

Examples of cardio embolic stroke etiology include: 1. Atrial Fibrillation 2. Cardiomyopathy with mural thrombus 3. Patent Foramen Ovale 4. Severe calcific Aortic (valve) Stenosis 5. Mechanical prosthetic valve Severe carotid artery stenosis is also implicated in embolic stroke. AFib can come and go.

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AFIB Embolism Atrial Fibrillation RN 59