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A new JAMA study suggests that statins might have a massive impact on HFpEF care, even among patients who don’t have atherosclerosis. The authors believe that statins’ HFpEF benefits “go beyond its impact on atherosclerosis,” specifically citing statins’ ability to reduce inflammation and lower AFib risks (both of which are linked to HFpEF).
In this week’s View, Dr. Eagle looks at a systematic review and meta-analysis of antibiotic prophylaxis and infective endocarditis incidence following invasive dental procedures. He then examines the issue of serious bleeding in patients with atrial fibrillation using diltiazem with apixaban or rivaroxaban.
(Harvard University Heart Letter) A clinical polygenic risk score test for diseases ranging from atrial fibrillation (AFib) to breast cancer was piloted by scientists.
AFib Facts and Impacts Atrial fibrillation is the most common cardiac arrhythmia, affecting 2% of individuals worldwide. Lifetime risk of atrial fibrillation by race and socioeconomic status: ARIC Study (Atherosclerosis Risk in Communities). 7 Atrial fibrillation has a significant impact on people’s lives. 2019;21(10):1468-1475.
OPTION Trial : LAAC after AFib ablation was associated with lower risks of major bleeding compared to oral anticoagulation. Many of our CMHC faculty who spoke at AHA 2024 are featured in this on-demand program, sharing expertise on key topics in cardiorenal health, obesity, diabetes, dyslipidemia, atherosclerosis, and more.
In Ischaemic strokes, there is some sort of blockage either in the major vessels that take the blood (this is called large vessel atherosclerosis) to the brain or even in the smaller vessels (called small vessel occlusion). Conditions such as AFib are often said to be associated with stroke as a consequence of cardioembolism.
This has indeed been confirmed and there was a study called the Atherosclerosis risk in communities study which did indeed confirm that cognitive decline in patients with AF was only observed in those who had sub clinical cerebral infarcts.
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