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Artery Damage : Hypertension damages the inner lining of your arteries, making them less elastic and more prone to plaque buildup. Coronary Artery Disease (CAD) : High blood pressure accelerates the development of CAD by promoting the buildup of plaques in the coronary arteries.
Coronary Artery Disease (CAD) CAD, which involves the narrowing or blockage of coronary arteries due to plaque buildup, can reduce blood flow to the heart. This may result in ischemia (lack of oxygen to the heart muscle), causing parts of the heart to weaken and enlarge. Beta-blockers , which slow the heart rate and reduce blood pressure.
MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. Lindahl et al. Thus, intracoronary imaging modalities are crucial in this setting.
To prove there is no plaque rupture, you need to do intravascular ultrasound (IVUS). An angiogram is a "lumenogram;" most plaque is EXTRALUMINAL!! One of the most common is rupture of a non-obstructive plaque, with thrombus formation and OMI that spontaneously lyses and leaves a wide open artery. It can only be seen by IVUS.
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