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ACE Inhibitor Not Protective Against Heart Damage from Chemotherapy

DAIC

The PROACT study reported no impact on cardiotoxicity biomarkers or secondary endpoints related to heart function among patients who took high doses of enalapril, an ACE inhibitor, along with high doses of anthracyclines. The mean dose of enalapril among those who were randomized to take the ACE inhibitor was 17.7mg.

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What Should Your Blood Pressure Be?

Dr. Paddy Barrett

Most people with high blood pressure will be treated with an ACE inhibitor, ARB, calcium channel blocker or a diuretic. Outcome over process, in my view, works best here. There is a range of blood pressure-lowering medications available. There are others also. Hypertension. N Engl J Med. 2015 Nov 26;373(22):2103-16.

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Digital Consults to Enhance Heart Failure Treatment: The ADMINISTER Trial

Cardiology Update

This includes beta-blockers, ACE inhibitors, ARBs, ARNIs, MRAs, and SGLT2 inhibitors. The primary outcome is the GDMT prescription rate score, with secondary outcomes covering the time to full GDMT optimization, patient and clinician satisfaction, time spent on healthcare, and the Kansas City Cardiomyopathy Questionnaire.

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FDA Accepts, Grants Priority Review Designation for Bayer's msNRA for Patients with Heart Failure

DAIC

In fact, a 2024 report on heart failure trends and outcomes published in the Journal of Cardiac Failure showed that in patients with heart failure with preserved ejection fraction, 5-year mortality was 75.7%. Heart Failure Epidemiology and Outcomes Statistics: A Report of the Heart Failure Society of America. 4 Approximately 6.7

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Regional and temporal variations of spontaneous coronary artery dissection care according to consensus recommendations: a systematic review and meta-analysis

Open Heart

received ACE inhibitors or aldosterone receptor blockers (ACEIs/ARBs), 54.4% (CI 45.4 Raising awareness about consensus recommendations and further prospective evidence about their effect on outcomes may help improve the quality of care for these patients. On random effects meta-analysis, 92.1% (95% CI 89.3

SCAD 98
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Hypertension in aortic coarctation

Frontiers in Cardiovascular Medicine

Additionally, exercise-induced hypertension and masked hypertension contribute to adverse outcomes. Oral beta-blockers, ACE inhibitors (ACE-Is), angiotensin receptor blockers (ARBs) and calcium channel blockers (CCBs) are most commonly used for chronic hypertension.

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EMPACT-MI Trial Outcomes Reported at ACC24: SGLT-2 Inhibitors Show Mixed Results After Heart Attack

DAIC

Researchers tracked outcomes for a median of just under 18 months. All secondary endpoints related specifically to heart failure outcomes were significantly reduced among patients who received empagliflozin. The study’s primary composite endpoint occurred in 8.2% of those who received empagliflozin and 9.1% of the control group.