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Can patients with advanced chronic kidneydisease (CKD) be initiated on angiotensin-converting enzyme inhibitors (ACEi) or angiotensin-receptor blockers (ARBs) without increasing their risk for needing kidney failure replacement therapy?
As evidence has mounted pointing to their benefits in reducing heart failure and other forms of heart disease, researchers have sought to determine whether these drugs could help to prevent heart failure even in people without diabetes or chronic kidneydisease.
Frailty, chronic kidneydisease and ischaemic heart disease increased significantly versus the first period (p<0.001). were on a beta blocker and on an ACEinhibitor/angiotensin receptor blocker/angiotensin receptor-neprilysin inhibitor, respectively. and 29.2%, p<0.001).
As evidence has mounted pointing to their benefits in reducing heart failure and other forms of heart disease, researchers have sought to determine whether these drugs could help to prevent heart failure even in people without diabetes or chronic kidneydisease.
Secondary hypertension : This type results from an underlying condition such as kidneydisease, hormonal disorders, or the use of certain medications. Common medications include diuretics, ACEinhibitors, beta-blockers, and calcium channel blockers.
2–4 The studies will be well-known to nephrologists and demonstrated that angiotensin-receptor blockers (ARBs) had anti-proteinuric effects and/or slowed the decline of kidney function in patients with diabetic kidneydisease. Clinicians and health care systems must be encouraged to make use of these treatments.”
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