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Risk of Initiating ACE Inhibitors/ARBs in Advanced CKD

American College of Cardiology

Can patients with advanced chronic kidney disease (CKD) be initiated on angiotensin-converting enzyme inhibitors (ACEi) or angiotensin-receptor blockers (ARBs) without increasing their risk for needing kidney failure replacement therapy?

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Characterisation of the octogenarians presenting to the diagnostic heart failure clinic: SHEAF registry

Open Heart

Frailty, chronic kidney disease and ischaemic heart disease increased significantly versus the first period (p<0.001). were on a beta blocker and on an ACE inhibitor/angiotensin receptor blocker/angiotensin receptor-neprilysin inhibitor, respectively. and 29.2%, p<0.001).

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Understanding the failings of yesterday to improve the outcomes of tomorrow: a CardioRenal story

The British Journal of Cardiology

2–4 The studies will be well-known to nephrologists and demonstrated that angiotensin-receptor blockers (ARBs) had anti-proteinuric effects and/or slowed the decline of kidney function in patients with diabetic kidney disease. Clinicians and health care systems must be encouraged to make use of these treatments.”

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SGLT-2 Inhibitors Show Mixed Results After Heart Attack

DAIC

As evidence has mounted pointing to their benefits in reducing heart failure and other forms of heart disease, researchers have sought to determine whether these drugs could help to prevent heart failure even in people without diabetes or chronic kidney disease.

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EMPACT-MI Trial Outcomes Reported at ACC24: SGLT-2 Inhibitors Show Mixed Results After Heart Attack

DAIC

As evidence has mounted pointing to their benefits in reducing heart failure and other forms of heart disease, researchers have sought to determine whether these drugs could help to prevent heart failure even in people without diabetes or chronic kidney disease.