ACE Inhibitor and Hospital - Cardiovascular Update

ACE Inhibitor Not Protective Against Heart Damage from Chemotherapy

DAIC

APRIL 9, 2024

The PROACT study reported no impact on cardiotoxicity biomarkers or secondary endpoints related to heart function among patients who took high doses of enalapril, an ACE inhibitor, along with high doses of anthracyclines. The mean dose of enalapril among those who were randomized to take the ACE inhibitor was 17.7mg.

ACE Inhibitor

ACE Inhibitor Cancer Biomarkers Heart Failure

FDA Accepts, Grants Priority Review Designation for Bayer's msNRA for Patients with Heart Failure

DAIC

MARCH 26, 2025

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients (REDEFINE-HF). A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients with Heart Failure (CONFIRMATION-HF) (CONFIRMATION). NCT 06008197. NCT05196035.

Heart Failure

Heart Failure Preserved Ejection Fraction Kidney Disease ACE Inhibitor

SGLT-2 Inhibitors Show Mixed Results After Heart Attack

DAIC

APRIL 6, 2024

However, researchers said the drug may be helpful in reducing heart failure risks, including hospitalization, following a heart attack. To have a 25% to 30% reduction in heart failure hospitalizations is pretty clinically meaningful, but if you put it together with all-cause mortality, it was not a positive study for our primary endpoint.”

Heart Attack

Heart Attack Heart attacks Heart Failure Outpatient

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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EMPACT-MI Trial Outcomes Reported at ACC24: SGLT-2 Inhibitors Show Mixed Results After Heart Attack

DAIC

APRIL 6, 2024

While composite of death and heart failure hospitalizations was not significantly reduced, empagliflozin may help reduce heart failure risks after a heart attack, according to results from the EMPACT-MI trial presented on day one of the American College of Cardiology Scientific Sessions, ACC.24, 24, being held in Atlanta, GA.

Heart Attack

Heart Attack Heart attacks Heart Failure Outcomes

Medications for Congenital Heart Disease: What Every Parent Should Know

Conquering CHD

JUNE 20, 2023

ACE Inhibitors WHAT THEY DO : ACE inhibitors block the angiotensin-converting enzyme (ACE) which causes narrowing of blood vessels. COMMON NAMES : Some common brand name ACE inhibitor drugs available to patients with CHD include lisinopril, ramipril and enalapril.

Congenital Heart Disease

Congenital Heart Disease Congenital Heart Disease ACE Inhibitor

Abstract 4134796: Safety of over 1000 consecutive, selected low risk patients with accelerated discharge from a chest pain unit with early generation cardiac troponin use, no cardiac functional or anatomic testing and no clinical risk scores

Circulation

NOVEMBER 11, 2024

Evaluation of these pts results in substantial costs for unnecessary hospitalization and extensive testing. Women received more discharge cardiac medications than men: antiplatelet agents, statins, beta blockers, ACE inhibitors, angiotensin II blockers, calcium channel blockers, and nitrates (p=0.0002 - 0.04).Follow-up

Chest Pain

Chest Pain ACE Inhibitor Cardiac Function Coronary Artery Disease

Hyperkalemia

EMS 12-Lead

MAY 8, 2022

The attending crews were concerned for SVT with corresponding ischemic hyperacute T waves (HATW) and subsequently activated STEMI pre-hospital. ACE inhibitors, or potassium-sparing diuretics), are particularly susceptible. No calcium was administered during pre-hospital transport. 2] But there is also Sinus Tachycardia!

ACE Inhibitor

ACE Inhibitor Ischemia STEMI Physiology

What is wrong with the NHS? Part two.

Dr. Malcolm Kendrick

OCTOBER 20, 2023

Whilst we had evidence (from drug company sponsored clinical trials) demonstrating that certain actions e.g., taking an ACE-inhibitor after a heart attack, reduced the risk of future heart attacks. 3 My main current job involves working in a unit looking after elderly people who, for one reason or another have ended up in hospital.

Heart Attack

Heart Attack Heart attacks Blood Pressure ACE Inhibitor

What does the angiogram show? The Echo? The CT coronary angiogram? How do you explain this?

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

associated typical Myocardial Infarction therapies such as statins and ACE inhibitors with significantly decreased 1 year mortality in MINOCA patients, which suggests that they do indeed have a similar pathophysiology to MI patients with obstructive coronary disease. Lindahl et al.

Coronary Angiogram

Coronary Angiogram Plaque Thrombosis STEMI

A man in his 70s with chest pain during a bike ride

Dr. Smith's ECG Blog

SEPTEMBER 30, 2019

The patient stated he had a long history of well-controlled hypertension for which he was compliant with his ACE-inhibitor. His initial cTnI at the receiving hospital was 27 ng/mL, and no further troponins were measured thereafter. He was also treated for erectile dysfunction but had not taken any medications recently.

Chest Pain

Chest Pain Pulmonary ACE Inhibitor Pacemaker

Pericarditis

Dr. Sanjay Gupta

DECEMBER 19, 2022

Who needs to stay in hospital? a pericardial effusion) then it is perhaps a good idea to stay in hospital as the features point to a more complicated course. If there is fluid but it is not causing extrinsic compression then just by controlling the inflammation with medications, the fluid will resolve.

Pericarditis

Pericarditis Heart Attack Heart attacks Chest Pain

Resynchronising the Heart in Heart Failure

Dr. Sanjay Gupta

MAY 23, 2022

We now do have some really good medications that help do both and these include: ACE Inhibitors/Entresto Beta Blockers MRAs – Mineraloreceptor antagonists SGLT2 inhibitors And ideally anyone with heart failure should be on all these medications unless they are intolerant or in some way the medications are contraindicated.

Heart Failure

Heart Failure Pacemaker Quality of Life ACE Inhibitor

Upon arrival to the emergency department, a senior emergency physician looked at the ECG and said "Nothing too exciting."

Dr. Smith's ECG Blog

NOVEMBER 30, 2022

Another ECG was recorded 5 minutes later just before arrival at the hospital: Similar The patient was transported to a nearby suburban hospital with PCI capabilities while my partner cared for her. These findings are diagnostic of an apical OMI as a result of LAD Occlusion. She was defibrillated and resuscitated. Lindahl et al.

Plaque

Plaque Chest Pain Thrombosis Stenosis

ACE Inhibitor Not Protective Against Heart Damage from Chemotherapy

FDA Accepts, Grants Priority Review Designation for Bayer's msNRA for Patients with Heart Failure

SGLT-2 Inhibitors Show Mixed Results After Heart Attack

Webinars

EMPACT-MI Trial Outcomes Reported at ACC24: SGLT-2 Inhibitors Show Mixed Results After Heart Attack

Medications for Congenital Heart Disease: What Every Parent Should Know

Abstract 4134796: Safety of over 1000 consecutive, selected low risk patients with accelerated discharge from a chest pain unit with early generation cardiac troponin use, no cardiac functional or anatomic testing and no clinical risk scores

Hyperkalemia

What is wrong with the NHS? Part two.

What does the angiogram show? The Echo? The CT coronary angiogram? How do you explain this?

A man in his 70s with chest pain during a bike ride

Pericarditis

Resynchronising the Heart in Heart Failure

Upon arrival to the emergency department, a senior emergency physician looked at the ECG and said "Nothing too exciting."

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