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Food and Drug Administration (FDA) accepted its supplemental new drug application (sNDA) and granted Priority Review designation for KERENDIA(finerenone) for the treatment of adult patients with heartfailure (HF) with a left ventricular ejection fraction (LVEF) of 40%, i.e., mildly reduced LVEF (HFmrEF) or preserved LVEF (HFpEF).
Secondary hypertension : This type results from an underlying condition such as kidneydisease, hormonal disorders, or the use of certain medications. The Link Between High Blood Pressure and Heart Health Your heart and blood vessels form a complex network that ensures oxygen and nutrients reach every part of your body.
However, researchers said the drug may be helpful in reducing heartfailure risks, including hospitalization, following a heart attack. All secondary endpoints related specifically to heartfailure outcomes were significantly reduced among patients who received empagliflozin.
Introduction Heartfailure (HF) incidence is increasing in older adults with high hospitalisation and mortality rates. Frailty, chronic kidneydisease and ischaemic heartdisease increased significantly versus the first period (p<0.001). Treatment is complicated by side effects and comorbidities.
While composite of death and heartfailure hospitalizations was not significantly reduced, empagliflozin may help reduce heartfailure risks after a heart attack, according to results from the EMPACT-MI trial presented on day one of the American College of Cardiology Scientific Sessions, ACC.24,
2–4 The studies will be well-known to nephrologists and demonstrated that angiotensin-receptor blockers (ARBs) had anti-proteinuric effects and/or slowed the decline of kidney function in patients with diabetic kidneydisease. Clinicians and health care systems must be encouraged to make use of these treatments.”
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