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ACE Inhibitor Not Protective Against Heart Damage from Chemotherapy

DAIC

The PROACT study reported no impact on cardiotoxicity biomarkers or secondary endpoints related to heart function among patients who took high doses of enalapril, an ACE inhibitor, along with high doses of anthracyclines. The mean dose of enalapril among those who were randomized to take the ACE inhibitor was 17.7mg.

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Top stories: Cardiac arrest—Patients at risk

HeartRhythm

Curtain etal1 performed an analysis of the VALIANT (Valsartan in Acute Myocardial Infarction) and PARADISE-MI (Prospective ARNi vs ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events After MI) trials to evaluate whether risk of sudden cardiac arrest (SCA) following acute myocardial infarction (MI) has changed over time.

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Digital Consults to Enhance Heart Failure Treatment: The ADMINISTER Trial

Cardiology Update

Despite proven benefits in reducing morbidity and mortality, many heart failure (HF) patients do not receive optimal guideline-directed medical therapy (GDMT). This includes beta-blockers, ACE inhibitors, ARBs, ARNIs, MRAs, and SGLT2 inhibitors. ESC Heart Failure 2024; 11 : 560–569.

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Instructors' Collection ECG: Regular Really Wide QRS Tachycardia

ECG Guru

Capoten (captopril) is an ACE inhibitor. So, we can assume the patient was probably being treated for angina, heart failure, and hypertension. Lasix (furosemide) is a potassium – wasting diuretic. Ntg is presumably sublingual nitroglycerine used for angina. Procardia (nifedipine) is a calcium-channel blocker.

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Prospective ARNI versus ACE Inhibitor Trial to Determine Superiority in Reducing Heart Failure Events After MI

American College of Cardiology

The goal of the PARADISE-MI trial was to assess the efficacy and safety of sacubitril/valsartan compared with ramipril in a contemporary acute myocardial infarction (AMI) population.

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How High Blood Pressure Affects Your Heart and What You Can Do About It

MIBHS

Over time, this added workload causes the heart muscle to thicken, particularly in the left ventricle. This condition, known as left ventricular hypertrophy, can lead to heart failure if untreated. Heart Failure : Over time, the extra strain on your heart can lead to its weakening and eventual failure.

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Characterisation of the octogenarians presenting to the diagnostic heart failure clinic: SHEAF registry

Open Heart

Introduction Heart failure (HF) incidence is increasing in older adults with high hospitalisation and mortality rates. were on a beta blocker and on an ACE inhibitor/angiotensin receptor blocker/angiotensin receptor-neprilysin inhibitor, respectively. Treatment is complicated by side effects and comorbidities.