Frontiers in Cardiovascular Medicine

MAY 1, 2024

BackgroundCatheter ablation is frequently used to manage recurrent atrial fibrillation (AF) resistant to drug therapy, with pulmonary vein isolation (PVI) as a key tactic. The reconnection of pulmonary veins was discovered primarily in the anterior region of the right superior PV and the superior portion of the left superior PV.

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DAIC

DECEMBER 29, 2023

Outcomes of ablation with the FARAPULSE PFA System – a nonthermal treatment in which electric fields selectively ablate heart tissue – will be compared to outcomes following use of anti-arrhythmic drug (AAD) therapy, which is commonly prescribed for patients living with persistent AF. The company now anticipates U.S. Circulation.

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DAIC

FEBRUARY 2, 2024

Titled "Real-world Data Affirms Safety and Effectiveness of Low/Zero Fluoroscopy Atrial Fibrillation Ablation," the study was presented as a late-breaker at the 29th Annual International AF Symposium. Biosense Webster's zero fluoroscopy workflow is the first and only such workflow available in a radiofrequency (RF) cardiac ablation device.

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Open Heart

APRIL 5, 2025

Objective Pulsed-field ablation (PFA) is a new technology of catheter ablation for atrial fibrillation (AF). This research is to investigate the feasibility of a new strategy (transoesophageal echocardiography-guided pulsed field ablation, TEEP) to guide PFA for AF with no contrast and zero fluoroscopy.

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DAIC

JUNE 4, 2024

Penn Presbyterian Medical Center Becomes First Hospital in the Northeast to Adopt Advanced Robotic Technology for Heart Treatment 5. Late-breaking Clinical Trial Results from FARADISE, admIRE Study and Advent Trial at Heart Rhythm 2024 Highlight Pulsed Field Ablation Developments for Atrial Fibrillation Treatment 8.

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DAIC

JULY 24, 2024

Volta Medical has announced it has entered into a Joint Development Agreement with GE Healthcare to enhance arrhythmia procedures with artificial intelligence (AI)-driven electrophysiology technologies. Our mission to combat complex heart rhythm diseases relies on optimizing interoperability.

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HeartRhythm

APRIL 30, 2024

Pulmonary vein (PV) isolation is the cornerstone of radiofrequency (RF) ablation for atrial fibrillation (AF). PV reconnection is the most common cause of recurrent AF following an ablation procedure. Additionally, the relationship between impedance drop during ablation lesion delivery and PV ostial WT is not well understood.

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HeartRhythm

APRIL 30, 2024

Pulsed field ablation (PFA) has recently been introduced as a novel ablation technology for pulmonary vein isolation (PVI) in patients with atrial fibrillation (AF). High rates of acute PVI have been observed based on electrograms of the PFA device only.

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HeartRhythm

AUGUST 21, 2024

No data have been reported on cooling characteristics and the impact of variant pulmonary vein (PV) anatomy on atrial fibrillation (AF) recurrences after POLARx cryoballoon (CB) ablation.

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HeartRhythm

APRIL 30, 2024

Cryoballoon (CB) ablation is the mainstay of single-shot pulmonary vein isolation (PVI). However, these two technologies have not been compared. A radiofrequency balloon (RFB) catheter has recently emerged as an alternative.

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DAIC

JULY 17, 2024

a company focused on cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases announced that the Unites States Patent Office has granted Patent No: 12,036,371 titled “Method of Accessing the Left Atrium with a Multi-Directional Steerable Catheter,” with a patent term that will expire in 2035.

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HeartRhythm

APRIL 30, 2024

Non-thermal pulsed field ablation (PFA) is an novel technology to perform pulmonary vein isolation (PVI) for atrial fibrillation (AF). Different PFA systems are available, but no comparative data exist.

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DAIC

DECEMBER 26, 2023

a company primarily focused on leveraging its novel and proprietary CellFX Nanosecond Pulsed Field Ablation (nsPFA) technology for the treatment of atrial fibrillation, announced the completion of the first five procedures in its first-in-human feasibility study with its novel CellFX nsPFA cardiac catheter.

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Journal of Cardiovascular Electrophysiology

MARCH 3, 2024

Abstract Introduction Through systematic scientific rigor, the CLOSE guided workflow was developed and has been shown to improve pulmonary vein isolation durability. However, this technique was developed at a time when using power-controlled ablation catheters with conventional power ranges was the norm.

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Journal of Cardiothoracic Surgery

JANUARY 22, 2025

Pulmonary vein isolation (PVI) with cryoballoon (CB) ablation technology is widely used to treat drug-resistant atrial fibrillation (AF). During CB ablation, there is a possibility of forming an ice cap of con.

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DAIC

MARCH 5, 2024

a global leader in cardiac arrhythmia treatment and part of Johnson & Johnson MedTech , today announced European CE mark approval of the VARIPULSE Platform for the treatment of symptomatic drug refractory recurrent paroxysmal atrial fibrillation ( AF ) using pulsed field ablation (PFA). iii] The study reported a low fluoroscopy time of 7.8

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HeartRhythm

APRIL 30, 2024

The 1st generation HeartLight laser balloon (LB) ablation is highly effective in achieving pulmonary vein isolation (PVI), and the safety and 12-month efficacy are comparable with paroxysmal atrial fibrillation (PAF) ablation technologies.

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HeartRhythm

APRIL 30, 2024

No single-shot pulsed field ablation (PFA) technology for pulmonary vein (PV) isolation can directly verify tissue contact.

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Journal of Cardiovascular Electrophysiology

DECEMBER 7, 2023

Abstract Background The newly introduced nonthermal pulsed field ablation (PFA) is a promising technology to achieve fast pulmonary vein isolation (PVI) with high acute success rates and good safety features. Data comparing PFA to VHPSD-PVI is lacking. One clinically nonsignificant PV stenosis occurred in the VHPSD group.

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HeartRhythm

APRIL 30, 2024

Pulsed field ablation (PFA) has recently been introduced as a novel routine ablation technology for paroxysmal atrial fibrillation (AF). It is also used as off-label therapy for persistent AF.

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HeartRhythm

JULY 1, 2024

One of the most significant recent advances in developing new technologies for the interventional treatment of atrial fibrillation (AF) has been the introduction of pulsed field ablation (PFA).1

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HeartRhythm

APRIL 30, 2024

We have employed digital twin technology to perform extra pulmonary vein (PV) ablation in patients with non-paroxysmal atrial fibrillation (AF). We reported that high dominant frequency (DF) site ablation improved rhythm outcomes, but high maximal slope of action potential restitution curve (Smax) site ablation did not.

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HeartRhythm

APRIL 30, 2024

Pulsed-field ablation (PFA) is novel ablative technology utilizing high-voltage, ultra-short electrical pulses to induce electroporation and cell apoptosis. The PFA dose needed to induce chronic lesion formation requires further assessment.

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Journal of Cardiovascular Electrophysiology

DECEMBER 17, 2023

This study investigated myocardial injury and inflammation following pulmonary vein isolation using (1) Standard radiofrequency ablation, (2) very high-power short-duration (vHPSD)-70W, (3) vHPSD-90W, and (4) pulsed-field ablation (PFA). Results Baseline characteristics were well-balanced between groups (age 63.1 ± 10.3

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HeartRhythm

APRIL 30, 2024

Pulsed field ablation (PFA) is an emerging technology that applies high voltage electrical pulses to cardiac tissue selectively and induces cell death through predominately non-thermal irreversible electroporation.

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HeartRhythm

APRIL 30, 2024

Pulsed-field ablation (PFA) is becoming increasingly relevant in the field of electrophysiology. Besides single-shot PFA devices for pulmonary vein isolation (PVI), point-by-point PFA is also gaining importance due to many possible applications. Data on the use is sparse, especially for atrial tachycardia (AT).

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Journal of Cardiovascular Electrophysiology

FEBRUARY 20, 2025

ABSTRACT Introduction The extensive use of pulsed field ablation (PFA) in clinical settings has unveiled new evidence suggesting potential involvement in red blood cell structural impairment resulting in hemolysis and potential acute kidney injury (AKI).

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Journal of Cardiovascular Electrophysiology

DECEMBER 7, 2023

Abstract Introduction Catheter ablation of atrial fibrillation (AF) has emerged as the most effective therapy. However, rare anatomical abnormalities such as situs inversus totalis, dextrocardia, or interrupted inferior vena cava can make ablation challenging.

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Journal of Cardiovascular Electrophysiology

NOVEMBER 6, 2024

Characteristics of acute insufficient lesions during vHPSD ablation were analyzed in the retrospective phase. Based on these data, an optimized approach combining both vHPSD ablation and AI-guided ablation was prospectively tested, resulting in an approximately 90% first-pass PVI rate. 0001) with shorter ablation time ( p =.04).

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Journal of Cardiovascular Electrophysiology

JANUARY 10, 2024

Abstract Introduction Despite advanced ablation strategies and major technological improvements, treatment of persistent atrial fibrillation (AF) remains challenging and the underlying pathophysiology is not fully understood. Randomized studies are necessary to evaluate long-term efficacy of dispersion-guided ablation using AI.

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HeartRhythm

APRIL 30, 2024

Left atrial (LA) low voltage area (LVA) burden correlates with AF recurrence risk post pulmonary vein isolation. Adjunctive ablation targeting LVAs, has been reported to improve outcomes. Omnipolar technology (OT) overcomes many limitations of BiV mapping, however there is little data on equivalent OT thresholds.

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Journal of Cardiovascular Electrophysiology

MARCH 19, 2025

ABSTRACT Introduction Pulmonary vein isolation (PVI) using a cryoballoon is well-established for the treatment of paroxysmal atrial fibrillation (PAF). Compared to other available technologies, the usage of a stable, low-pressure cryoballoon (POLARx, Boston Scientific) has demonstrated lower nadir temperatures and longer thawing times.

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DAIC

JUNE 19, 2024

By the 1960s, advances in technology and medical research led to the emergence of automated ECG interpretation (AEI), based on physician-developed rules of classification. By 1909 ECGs were being used to diagnose cases of arrhythmia; by 1910 to diagnose indicators of a heart attack.

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DAIC

JULY 8, 2024

PFA is the latest ablation modality approved by the Food and Drug Administration that can be used to restore a regular heartbeat. Given the relative novelty of pulsed field ablation, these are important safety outcomes.” Patients with AF can undergo a catheter procedure, called catheter ablation, to treat this abnormal heart rhythm.

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Journal of Cardiovascular Electrophysiology

DECEMBER 7, 2023

Abstract Introduction Pulsed field ablation (PFA) is a new ablation technology for atrial fibrillation (AF). Data regarding early recurrences of atrial tachyarrhythmia (ERAT) after PFA-pulmonary vein isolation (PVI) are sparse. Methods Consecutive patients with symptomatic AF were enrolled to undergo PFA-PVI.

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Society of Thoracic Surgeons - Research

APRIL 20, 2023

Published Research kschukar Thu, 04/20/2023 - 11:12 Recently published (2016 – present) manuscripts utilizing STS data: Adult Cardiac Surgery, General Thoracic Surgery, Congenital Heart Surgery, and Intermacs/Pedimacs.

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CardiacWire

NOVEMBER 6, 2024

Cortex gives Boston Scientific a new mapping technology that detects AFib signs and triggers outside of the pulmonary veins, and can help EP teams develop ablation strategies for more complex AFib cases. for an undisclosed sum.

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