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Preventive catheter ablation for ventricular arrhythmias in patients with end‐stage heart failure referred for heart transplantation evaluation: Rationale for and design of the CASTLE‐VT trial

European Journal of Heart Failure

Cardiovascular mortality, driven by sudden cardiac death, is the main reason for dying while waiting for heart transplantation (HTx). Ablation will be performed with the use of a substrate-based approach in which the myocardial scar is mapped and ablated while the heart remains predominantly in sinus rhythm.

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Effects of atrial fibrillation ablation on arrhythmia burden and ventricular function in end‐stage heart failure: Lessons from CASTLE‐HTx

European Journal of Heart Failure

Overview of the study population and effects observed after catheter ablation for atrial fibrillation. Herein we describe the effects of catheter ablation on AF burden, arrhythmia recurrences, and ventricular function in end-stage HF. to 39.18.3% ( p <0.001) following ablation. PVI, pulmonary vein isolation.

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Catheter ablation of typical atrial flutter improves cardiac chamber size and function

Journal of Cardiovascular Electrophysiology

Abstract Introduction Cavo-tricuspid isthmus (CTI) dependent atrial flutter (AFL) is one of the most common atrial arrhythmias involving the right atrium (RA) for which radiofrequency catheter ablation has been widely used as a therapy of choice. However, there is limited data on the effect of this intervention on cardiac size and function.

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Posttransplant atrial fibrillation: Evidence of early posttransplant recipient?to?donor atrioatrial connections

Journal of Cardiovascular Electrophysiology

Abstract Introduction Atrial fibrillation and atrial flutter originating from the donor s heart is a commonly reported complication post heart transplant. Case A 47-year-old male presented with atrial tachycardia 6 months post heart transplant.

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What happens to patients awaiting urgent transplantation for refractory electrical storm when they are not transplanted?

HeartRhythm

Management typically involves addressing triggers, antiarrhythmic drugs and catheter ablation (CA), associated for refractory cases to deep sedation, sympathetic modulation, fast/overdrive pacing or temporary percutaneous mechanical circulatory support.

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J&J Expands Into Interventional HF Treatments With V-Wave Acquisition

CardiacWire

These improvements would allow the Ventura IAS to address the notable HFrEF treatment gap between GDMT and far more invasive therapies like LVAD and heart transplantation. The Ventura already has a European CE Mark, and gained FDA Breakthrough Device Designation back in 2019, although its still working towards FDA approval.

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Dofetilide for the treatment of premature ventricular complexes and ventricular tachycardia in patients with structural heart disease

Journal of Cardiovascular Electrophysiology

Prior catheter ablation had been performed in 33 patients (41%). The composite outcome of VT/VF recurrence, heart transplantation, or death occurred in 6/12 patients (50%) without dofetilide and 49/69 patients (71%) with dofetilide. A80% decrease in PVC burden was defined as a satisfactory response.