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Atrial Fibrillation Ablation in Heart Failure With Reduced vs Preserved Ejection Fraction

JAMA Cardiology

This systematic review and meta-analysis investigates the efficacy of catheter ablation compared with rate or rhythm control among patients with atrial fibrillation and heart failure.

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Impaired T cell IRE1?/XBP1 signaling directs inflammation in experimental heart failure with preserved ejection fraction

Journal of Clinical Investigation - Cardiology

Heart failure with preserved ejection fraction (HFpEF) is a widespread syndrome with limited therapeutic options and poorly understood immune pathophysiology. Notably, selective ablation of XBP1 in T cells enhanced their persistence in the heart and lymphoid organs of mice with preclinical HFpEF.

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Impact of HFpEF on Ablation Outcomes; PVI Only Ablation in HFrEF?

American College of Cardiology

Patients who undergo catheter ablation for atrial fibrillation (AFib) who also have heart failure with preserved ejection fraction (HFpEF) experienced a greater benefit from ablation in terms of clinical outcome, AFib recurrence and functional status, according to findings from the CABANA trial.

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Catheter Ablation Versus Antiarrhythmic Therapy for Atrial Fibrillation in Heart Failure with Preserved Ejection Fraction

HeartRhythm

Clinical outcomes among patients with atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) treated with catheter ablation (CA) versus antiarrhythmic therapy (AAT) are not well-known.

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Endovascular Ablation of the Greater Splanchnic Nerve in HFpEF

JAMA Cardiology

This randomized clinical trial investigates the feasibility, safety, and efficacy of endovascular right-sided splanchnic nerve ablation for volume management in heart failure with preserved ejection fraction (HFpEF).

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Atrial Fibrillation Ablation in Heart Failure: Difference in 3-Year Outcomes between Reduced and Preserved Ejection Fraction

HeartRhythm

Atrial fibrillation (AF) is a common arrhythmia in patients with heart failure (HF). Catheter ablation of AF has been proven to be an effective therapeutic option for AF management in HF, particularly in heart failure with reduced ejection fraction (HFrEF) [2, 3].

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MP-483497-005 IMPACT OF CATHETER ABLATION FOR ATRIAL FIBRILLATION IN PATIENTS WITH HEART FAILURE WITH PRESERVED EJECTION FRACTION

HeartRhythm

The efficacy of catheter ablation as a treatment approach for patients with concurrent atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) has been inadequately investigated.