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We have previously shown that ablation of CaMKIIδ oxidation by CRISPR-Cas9 base editing enables the heart to recover function from otherwise severe damage following ischemia/reperfusion (IR) injury. Here, we extended this therapeutic concept toward potential clinical translation.
ET Main Tent (Hall B1) This session offers more insights from key clinical trials presented at ACC.24 24 and find out what it all means for your patients.
And superimposed subendocardial ischemia pattern, of course. Before continuing flecainide, he had me get on a treadmill at full dose and at full exercise (18 minutes) and measured the QRS to be certain that the QRS did not lengthen at all. Is this patient a candidate for cardioversion or ablation? ( Coincidence?).
As discussed in ECG Blog #363 — this rare genetic disorder almost always presents in association with emotional stress or with exercise (ie, CPVT is usually "induced" by catecholamine discharge ). A left-sided lateral wall AP was found on EP study — and successfully ablated. Beyond-the-Core: Can You L ocalize the A P ?
The patient was found to have a "concealed" posteroseptal pathway (WPW without delta waves) confirmed to have SVT at EP study and was ablated. Here is the Electrophysilogist's note: "Only 1 pathway attachment could be ablated, the second one deep within the CS could not be ablated with high power.
Previously healthy, taking no medication and exercising regularly. No anginal symptoms asymptomatic during physical exercise. That said there were no clinical symptoms or ECG findings suggestive of ongoing ischemia. The patient has been scheduled for a PVC ablation procedure. How will you manage this patient?
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