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Impact of Obesity on Atrial Fibrillation Pathogenesis and Treatment Options

Journal of the American Heart Association

AF increases the risk of stroke, heart failure, dementia, and hospitalization. Weight loss has been shown to reverse these changes and reduce AF risk and recurrence after ablation. However, studies on how obesity affects pharmacologic or interventional AF treatments are limited.

Obesity 45
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Neuropsychiatry of atrial fibrillation: dementia and beyond

Frontiers in Cardiovascular Medicine

It is associated with increased mortality and morbidity, including increased risk of dementia. The mechanisms underlying the association between AF and dementia are complex, including stroke, chronic cerebral hypoperfusion, and systemic inflammation.