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Reduced dementia risk in patients with optimized anticoagulation therapy undergoing atrial fibrillation ablation

HeartRhythm

Atrial fibrillation (AF) is associated with the development of dementia and observational studies have shown that oral anticoagulation (OAC) and catheter ablation reduce dementia risk.

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PO-02-153 EFFECT OF CATHETER ABLATION FOR ATRIAL FIBRILLATION ON LONG-TERM NEUROLOGICAL OUTOMES

HeartRhythm

Catheter ablation (CA) of atrial fibrillation (AF) has been proved to benefit patient with symptomatic AF and heart failure. However, the data on neurological outcomes including cerebrovascular disease (CVA) and dementia remain a controversy.

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Impact of Obesity on Atrial Fibrillation Pathogenesis and Treatment Options

Journal of the American Heart Association

AF increases the risk of stroke, heart failure, dementia, and hospitalization. Weight loss has been shown to reverse these changes and reduce AF risk and recurrence after ablation. Journal of the American Heart Association, Ahead of Print. ABSTRACTAtrial fibrillation (AF) is the most common cardiac arrhythmia.

Obesity 45
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AF and Dementia

Dr. Sanjay Gupta

However over the past few years there have been several studies which have studied AF patients and discovered patients with AF have a significantly higher prevalence of cognitive impairment and dementia and as we do not have any clinical guidelines as yet, we have to try and work out for ourselves as to why there is this association.

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ACC/AHA Release Updated 2023 Guidelines for Atrial Fibrillation

Cardiometabolic Health Congress

Furthermore, it includes the latest recommendations which specifically address AF and thromboembolic risk assessment, anticoagulation, left atrial appendage occlusion, AF catheter or surgical ablation, and risk factor modification and AF prevention. As such, the Class of Recommendation for catheter ablation has been upgraded.

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Abstract 4141439: Catheter ablation and clinical outcomes among older Medicare beneficiaries with atrial fibrillation

Circulation

Background:Catheter ablation (CA) is increasingly used for treatment of atrial fibrillation (AF). years; 55% female, 28% frailty, 13% dementia), including 8% receiving CA. Circulation, Volume 150, Issue Suppl_1 , Page A4141439-A4141439, November 12, 2024. However, CA has not been widely adopted in the older population with AF.

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Neuropsychiatry of atrial fibrillation: dementia and beyond

Frontiers in Cardiovascular Medicine

It is associated with increased mortality and morbidity, including increased risk of dementia. The mechanisms underlying the association between AF and dementia are complex, including stroke, chronic cerebral hypoperfusion, and systemic inflammation.